{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T23:24:39Z","timestamp":1791329079735,"version":"4.3.1"},"reference-count":22,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To determine the outcomes of Ahmed glaucoma valve (AGV) and transscleral diode cyclophotocoagulation (CPC) in neovascular glaucoma (NVG).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This was a single-center retrospective comparative case series involving chart review of consecutive patients who underwent AGV or CPC for treatment of NVG and had \u22656 months of follow-up. Surgical failure at 6 months, defined as an IOP of &gt;21 or &lt;6 mm Hg with hypotony maculopathy after 1 month, progression to no light perception (NLP) vision, glaucoma reoperation, or removal of AGV were the main outcome measures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      In total, 121 eyes of 121 patients were included (70 AGV and 51 CPC). Baseline demographics, visual acuity (VA), and intraocular pressure (IOP) were comparable between groups. At 6 months, failure was significantly higher in the CPC group than in the AGV group (43.1% vs. 17.1%,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.020). Both groups had similar IOP and medication number at 6 months, but VA was significantly lower in the CPC group compared to the AGV group (2.4 \u00b1 0.8 vs. 1.9 \u00b1 1.0,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.017). More CPC eyes required reoperation for glaucoma than AGV eyes (11.8% vs. 1.4%,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.041). Multivariate regression analysis identified higher preoperative IOP (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.001) and CPC surgery (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.004) as independent predictors of surgical failure at 6 months. Age, sex, race, NVG etiology, bilaterality of the underlying retinal pathology, perioperative retina treatment, and prior or combined vitrectomy were not significant\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>AGV and CPC had comparable IOP and medication reduction in NVG eyes at 6 months. CPC was more frequently associated with failure, reoperation for glaucoma, and worse visual outcomes. High preoperative IOP and CPC surgery independently predicted surgical failure.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_2107_21","type":"journal-article","created":{"date-parts":[[2022,3,28]],"date-time":"2022-03-28T07:53:23Z","timestamp":1648454003000},"page":"1253-1259","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":14,"title":["Outcomes of Ahmed glaucoma valve and transscleral cyclophotocoagulation in neovascular glaucoma"],"prefix":"10.4103","volume":"70","author":[{"given":"Wesam S","family":"Shalaby","sequence":"first","affiliation":[{"name":"Glaucoma Research Center, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA, USA"},{"name":"Department of Ophthalmology, Tanta Medical School, Tanta University, Tanta, Gharbia, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allen Y","family":"Ganjei","sequence":"additional","affiliation":[{"name":"College of Medicine, Drexel University, Philadelphia, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Wogu","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan S","family":"Myers","sequence":"additional","affiliation":[{"name":"Glaucoma Research Center, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA, USA"},{"name":"Department of Ophthalmology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marlene R","family":"Moster","sequence":"additional","affiliation":[{"name":"Glaucoma Research Center, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA, USA"},{"name":"Department of Ophthalmology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reza","family":"Razeghinejad","sequence":"additional","affiliation":[{"name":"Glaucoma Research Center, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA, USA"},{"name":"Department of Ophthalmology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Lee","sequence":"additional","affiliation":[{"name":"Glaucoma Research Center, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA, USA"},{"name":"Department of Ophthalmology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natasha N","family":"Kolomeyer","sequence":"additional","affiliation":[{"name":"Glaucoma Research Center, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA, USA"},{"name":"Department of Ophthalmology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tarek E","family":"Eid","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Tanta Medical School, Tanta University, Tanta, Gharbia, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L Jay","family":"Katz","sequence":"additional","affiliation":[{"name":"Glaucoma Research Center, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA, USA"},{"name":"Department of Ophthalmology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aakriti G","family":"Shukla","sequence":"additional","affiliation":[{"name":"Glaucoma Research Center, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA, USA"},{"name":"Department of Ophthalmology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,3,22]]},"reference":[{"key":"B1-20240828","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.ogla.2020.09.010","article-title":"Outcomes of valved and non-valved tube shunts in neovascular glaucoma","volume":"4","author":"Shalaby","year":"2021","journal-title":"Ophthalmol Glaucoma"},{"key":"B2-20240828","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/j.ophtha.2014.08.043","article-title":"Five-year treatment outcomes in the Ahmed Baerveldt comparison study","volume":"122","author":"Budenz","year":"2015","journal-title":"Ophthalmology"},{"key":"B3-20240828","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1186\/s40942-016-0051-x","article-title":"Neovascular glaucoma: A review","volume":"2","author":"Rodrigues","year":"2016","journal-title":"Int J Retina Vitreous"},{"key":"B4-20240828","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/S0161-6420(84)34293-2","article-title":"Neovascular glaucoma. Etiologic considerations","volume":"91","author":"Brown","year":"1984","journal-title":"Ophthalmology"},{"key":"B5-20240828","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1016\/j.preteyeres.2007.06.001","article-title":"Neovascular glaucoma","volume":"26","author":"Hayreh","year":"2007","journal-title":"Prog Retin Eye Res"},{"key":"B6-20240828","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1159\/000095865","article-title":"Trabeculectomy with Mitomycin C for treatment of neovascular glaucoma in diabetic patients","volume":"220","author":"Kiuchi","year":"2006","journal-title":"Ophthalmologica"},{"key":"B7-20240828","doi-asserted-by":"crossref","first-page":"2207","DOI":"10.2147\/OPTH.S151200","article-title":"Short-term outcomes after EX-PRESS implantation versus trabeculectomy alone in patients with neovascular glaucoma","volume":"11","author":"Shinohara","year":"2017","journal-title":"Clin Ophthalmol"},{"key":"B8-20240828","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.7150\/ijms.35267","article-title":"Efficacy of Ahmed glaucoma valve implantation on neovascular glaucoma","volume":"16","author":"Xie","year":"2019","journal-title":"Int J Med Sci"},{"key":"B9-20240828","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1097\/IAE.0000000000000235","article-title":"Combined pars plana vitrectomy and pars plana Baerveldt tube placement in eyes with neovascular glaucoma","volume":"35","author":"Kolomeyer","year":"2015","journal-title":"Retina"},{"key":"B10-20240828","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1016\/S0161-6420(03)00103-9","article-title":"Long-term results of noncontact neodymium: yttrium-aluminum-garnet cyclophotocoagulation in neovascular glaucoma","volume":"110","author":"Delgado","year":"2003","journal-title":"Ophthalmology"},{"key":"B11-20240828","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1097\/IJG.0b013e31817d235c","article-title":"A comparative study between diode laser cyclophotocoagulation and the Ahmed glaucoma valve implant in neovascular glaucoma: A long-term follow-up","volume":"18","author":"Yildirim","year":"2009","journal-title":"J Glaucoma"},{"key":"B12-20240828","doi-asserted-by":"crossref","first-page":"1692","DOI":"10.1016\/S0161-6420(97)30078-5","article-title":"Tube-shunt surgery versus neodymium: YAG cyclophotocoagulation in the management of neovascular glaucoma","volume":"104","author":"Eid","year":"1997","journal-title":"Ophthalmology"},{"key":"B13-20240828","doi-asserted-by":"crossref","first-page":"2545","DOI":"10.2147\/OPTH.S188999","article-title":"Randomized comparative trial of diode laser transscleral cyclophotocoagulation versus Ahmed glaucoma valve for neovascular glaucoma in Chinese-A pilot study","volume":"12","author":"Choy","year":"2018","journal-title":"Clin Ophthalmol"},{"key":"B14-20240828","doi-asserted-by":"crossref","first-page":"1767","DOI":"10.1016\/S0161-6420(01)00775-8","article-title":"Evidence-based recommendations for the diagnosis and treatment of neovascular glaucoma","volume":"108","author":"Sivak-Callcott","year":"2001","journal-title":"Ophthalmology"},{"key":"B15-20240828","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1097\/00061198-200406000-00011","article-title":"A prospective, comparative study between endoscopic cyclophotocoagulation and the Ahmed drainage implant in refractory glaucoma","volume":"13","author":"Lima","year":"2004","journal-title":"J Glaucoma"},{"key":"B16-20240828","article-title":"Prognostic factor analysis of intraocular pressure with neovascular glaucoma","author":"Nakano","year":"2016","journal-title":"J Ophthalmol 2016"},{"key":"B17-20240828","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1007\/s00417-019-04256-8","article-title":"Surgical treatment of neovascular glaucoma: A systematic review and meta-analysis","volume":"257","author":"Shchomak","year":"2019","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"B18-20240828","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/0039-6257(81)90063-1","article-title":"Neovascular glaucoma. Current management","volume":"26","author":"Weber","year":"1981","journal-title":"Surv Ophthalmol"},{"key":"B19-20240828","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1136\/bjo.74.2.103","article-title":"Cyclocryotherapy: A review of cases over a 10-year period","volume":"74","author":"Benson","year":"1990","journal-title":"Br J Ophthalmol"},{"key":"B20-20240828","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1016\/S0161-6420(85)33951-9","article-title":"Cyclocryotherapy in the treatment of advanced glaucoma","volume":"92","author":"Caprioli","year":"1985","journal-title":"Ophthalmology"},{"key":"B21-20240828","doi-asserted-by":"crossref","first-page":"2103","DOI":"10.1007\/s12325-018-0837-3","article-title":"Cyclodestructive procedures in glaucoma: A review of current and emerging options","volume":"35","author":"Dastiridou","year":"2018","journal-title":"Adv Ther"},{"key":"B22-20240828","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/S0002-9394(00)00538-9","article-title":"The Advanced Glaucoma Intervention Study (AGIS): 7. The relationship between control of intraocular pressure and visual field deterioration. The AGIS Investigators","volume":"130","year":"2000","journal-title":"Am J Ophthalmol"}],"container-title":["Indian Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijo.IJO_2107_21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:11:15Z","timestamp":1787166675000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijo.IJO_2107_21"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,22]]},"references-count":22,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4103\/ijo.ijo_2107_21","relation":{},"ISSN":["0301-4738","1998-3689"],"issn-type":[{"value":"0301-4738","type":"print"},{"value":"1998-3689","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,22]]},"assertion":[{"value":"2021-08-10","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-11-21","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}