{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:23:43Z","timestamp":1787840623169,"version":"build-2784847793"},"reference-count":23,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","license":[{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To evaluate presence of perilimbal pigmentation (PLP) in Indian patients with vernal keratoconjunctivitis (VKC).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A cross sectional study was conducted from 2019 to 2020 at a tertiary eye care center in Western Maharashtra, India. In this study, 152 cases of VKC were identified. The presence, type, color, and extent of PLP were recorded. The incidence of presence of PLP was calculated. Its correlations with severity and duration of VKC were analyzed using Wilcoxon\u2013Mann\u2013Whitney U test and Chi square test.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Of 152 cases, 79.61% were males. Mean age at presentation was 11.4 \u00b1 5.6 years. The characteristic PLP was present in 81 cases (53.29%; 95% confidence interval [CI]: 45.03%\u201361.42%;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001), of which 15 cases (18.5%) had this pigmentation in all the four quadrants. There was a significant difference between the groups with respect to quadrants involvement in terms of the extent of PLP in clock hours (\u03a7\n                      <jats:sup>2<\/jats:sup>\n                      = 73.85,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001). However, the extent did not correlate with age (rho = 0.08,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.487), sex (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.115), time since onset in months (rho = 0.03,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.77), duration of VKC and type or color of PLP (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.12).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Perilimbal pigmentation seems to be a consistent clinical finding seen in a significant number of VKC cases. It may benefit ophthalmologists in treating VKC cases when the palpebral\/limbal signs are elusive.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_2128_22","type":"journal-article","created":{"date-parts":[[2023,5,17]],"date-time":"2023-05-17T03:14:55Z","timestamp":1684293295000},"page":"1816-1821","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":4,"title":["An observational study on the presence of perilimbal conjunctival pigmentation in vernal keratoconjunctivitis"],"prefix":"10.4103","volume":"71","author":[{"given":"Srujana","family":"Dubbaka","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Armed Forces Medical College, Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohini","family":"Agrawal","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Military Hospital, Jalandhar, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alok","family":"Sati","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Army Hospital R and R, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sumedha","family":"Vats","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Armed Forces Clinic, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saurabh","family":"Mahajan","sequence":"additional","affiliation":[{"name":"Department of Community Medicine, Armed Forces Medical College, Pune, Maharashtra, India Institution where the work was carried out: Department of Ophthalmology, Armed Forces Medical College, Pune, Maharashtra, 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