{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T07:50:33Z","timestamp":1791359433043,"version":"4.3.1"},"reference-count":21,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"10","license":[{"start":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T00:00:00Z","timestamp":1779235200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To evaluate the early postoperative safety and long-term efficacy of Ologen augmented trabeculectomy (Olo-trab) with releasable scleral flap suture in eyes with advanced primary open\/closed angle glaucoma.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This was a single-center, prospective, interventional, and noncomparative study of patients who underwent Olo-trab for advanced glaucoma (cup disc ratio &gt; 0.8), in whom target pressure could not be met despite maximum permissible medical therapy. Postoperatively, patients were followed up for 12 months and evaluated for early postoperative complications within 1 month. The primary surgery success rate was assessed at 6 months and 1 year.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The study cohort comprised 31 eyes of 27 patients. The mean age of the population was 59.48 \u00b1 10.41 years. Eight cases were on two-drug antiglaucoma medications (AGMs), 13 on three drugs, and 10 were using four AGMs. The mean preoperative intraoperative pressure (IOP) of the cohort was 30.5 \u00b1 9.1 mmHg. A total of 15 cases underwent combined phacoemulsification and trabeculectomy. Early postoperative hypotony was the only complication observed in 2\/31 eyes (6%). Twelve months post surgery, 27 out of 31 eyes (87.10%) had a complete success, and the remaining 4 (12.9%) achieved a qualified\/partial success. Mean postoperative IOP readings at all follow-up visits were significantly lower than those at preoperative levels (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Olo-Trab with a releasable scleral flap suture has shown encouraging results for IOP control with a marginalized risk of postoperative hypotony in advanced cases of primary glaucoma.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_2143_25","type":"journal-article","created":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T10:00:19Z","timestamp":1779357619000},"page":"1490-1496","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Safety and efficacy of modified suture techniques in Ologen augmented trabeculectomy for eyes with advanced primary open angle and angle closure glaucoma"],"prefix":"10.4103","volume":"74","author":[{"given":"Rakesh","family":"Shakya","sequence":"first","affiliation":[{"name":"Department of Glaucoma, Sadguru Netra Chikitsalaya and Post Graduate Institute of Ophthalmology, Jankikund, Chitrakoot, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaurav","family":"Kohli","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Vitreo-Retina, Uvea, ROP, Eras Medical College and Hospitals, Lucknow, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chintan","family":"Shah","sequence":"additional","affiliation":[{"name":"Department of Pediatric Ophthalmology and Strabismus, Sadguru Netra Chikitsalaya and Post Graduate Institute of Ophthalmology, Jankikund, Chitrakoot, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Navjot Singh","family":"Ahluwalia","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, Sadguru Netra Chikitsalaya and Post Graduate Institute of Ophthalmology, Jankikund, Chitrakoot, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rohil","family":"Paes","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, Sadguru Netra Chikitsalaya and Post Graduate Institute of Ophthalmology, Jankikund, Chitrakoot, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V K","family":"Raju","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, West Virginia University, Morgantown, WV, USA"},{"name":"Eye Foundation of America, Department of Ophthalmology, University of Illinois, Chicago, IL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepak","family":"Edward","sequence":"additional","affiliation":[{"name":"Illinois Eye and Ear Infirmary, Department of 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