{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T20:07:02Z","timestamp":1787170022135,"version":"build-2736575974"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"12","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:p>Coronavirus disease 19 (COVID-19) and its ophthalmic manifestations have been variably portrayed. We report a case of a 56-year-old female presenting with sudden-onset vision loss associated with painful extraocular muscle movements in both eyes following COVID-19. Visual acuity was counting fingers close to face. Color perception tested was inaccurate. Ocular examination revealed sluggishly reacting pupils and an otherwise unremarkable fundus picture in both eyes, giving us an impression of bilateral retrobulbar neuritis. Magnetic resonance imaging of the brain and orbit were unremarkable, while blood investigations revealed nothing suggestive. The patient dramatically improved with steroid therapy with full visual recovery and a color vision defect. This presentation of bilateral retrobulbar neuritis as a sequela of COVID-19 is presented for its rarity.<\/jats:p>","DOI":"10.4103\/ijo.ijo_2155_21","type":"journal-article","created":{"date-parts":[[2021,11,30]],"date-time":"2021-11-30T06:54:59Z","timestamp":1638255299000},"page":"3761-3764","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":15,"title":["Acute bilateral retrobulbar optic neuritis - An atypical sequela of COVID-19"],"prefix":"10.4103","volume":"69","author":[{"given":"Dipika","family":"Sainath","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth, Pondicherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anujeet","family":"Paul","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth, Pondicherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Srikanth","family":"Krishnagopal","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth, Pondicherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashok","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth, Pondicherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2021,11,26]]},"reference":[{"key":"B1-20240828","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1097\/ICU.0000000000000707","article-title":"Neuro-ophthalmic manifestations of coronavirus disease 19","volume":"31","author":"Tisdale","year":"2020","journal-title":"Curr Opin Ophthalmol"},{"key":"B2-20240828","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1007\/s13365-021-00959-z","article-title":"Optic neuritis following SARS-CoV-2 infection","volume":"27","author":"Rodr\u00edguez-Rodr\u00edguez","year":"2021","journal-title":"J Neurovirol"},{"issue":"3 Suppl","key":"B3-20240828","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.21873\/invivo.11952","article-title":"Ocular manifestations of COVID-19 (SARS-CoV-2): A critical review of current literature","volume":"34","author":"Douglas","year":"2020","journal-title":"In Vivo"},{"key":"B4-20240828","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1136\/bjo.2005.085399","article-title":"Clinical profile of simultaneous bilateral optic neuritis in adults","volume":"90","author":"de la Cruz","year":"2006","journal-title":"Br J Ophthalmol"},{"key":"B5-20240828","doi-asserted-by":"crossref","first-page":"117","DOI":"10.4103\/0301-4738.77020","article-title":"Management of optic neuritis","volume":"59","author":"Saxena","year":"2011","journal-title":"Indian J Ophthalmol"},{"key":"B6-20240828","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1002\/jmv.26290","article-title":"Optic nerve analysis in COVID-19 patients","volume":"93","author":"Burgos-Blasco","year":"2021","journal-title":"J Med Virol"},{"key":"B7-20240828","article-title":"COVID-19-Induced acute bilateral optic neuritis","volume":"8","author":"Sawalha","year":"2020","journal-title":"J Investig Med High Impact Case Rep"},{"key":"B8-20240828","doi-asserted-by":"crossref","first-page":"27","DOI":"10.4103\/ijo.IJO_451_20","article-title":"Atypical optic neuritis: An overview","volume":"69","author":"Sarkar","year":"2021","journal-title":"Indian J Ophthalmol"},{"key":"B9-20240828","doi-asserted-by":"crossref","first-page":"e25865","DOI":"10.1097\/MD.0000000000025865","article-title":"Myelin oligodendrocyte glycoprotein antibody-associated optic neuritis in a COVID-19 patient: A case report","volume":"100","author":"Kogure","year":"2021","journal-title":"Medicine (Baltimore)"},{"key":"B10-20240828","doi-asserted-by":"crossref","first-page":"e04347","DOI":"10.1002\/ccr3.4347","article-title":"The diagnostic dilemma of bilateral optic neuritis and idiopathic intracranial hypertension coexistence in a patient with recent COVID-19 infection","volume":"9","author":"Sardar","year":"2021","journal-title":"Clin Case Rep"},{"key":"B11-20240828","doi-asserted-by":"crossref","first-page":"101320","DOI":"10.1016\/j.inat.2021.101320","article-title":"Optic neuritis post-COVID-19 infection. A case report with meta-analysis","volume":"26","author":"Azab","year":"2021","journal-title":"Interdiscip Neurosurg"}],"container-title":["Indian Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijo.IJO_2155_21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:16:50Z","timestamp":1787167010000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijo.IJO_2155_21"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,26]]},"references-count":11,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.4103\/ijo.ijo_2155_21","relation":{},"ISSN":["0301-4738","1998-3689"],"issn-type":[{"value":"0301-4738","type":"print"},{"value":"1998-3689","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,26]]},"assertion":[{"value":"2021-08-17","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-10-27","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}