{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T09:27:50Z","timestamp":1791019670363,"version":"4.1.0"},"reference-count":25,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,4]]},"abstract":"\n Purpose:<\/jats:title>\n Comparison of three ultrasound (US) frequencies for phacoemulsification of hard cataracts to determine a frequency that makes phacoemulsification more efficacious and safer.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n A randomized controlled trial was undertaken at a medical college and hospital. In total, 207 patients with grade 5.6\u20136.9 (LOCS III) senile cataract were randomized into three groups. Group I underwent phacoemulsification with 28-kHz frequency, group II with 42-kHz frequency, and group III with 53-kHz frequency. The effective phacoemulsification time (EPT) and estimated fluid usage (EFU) were compared intraoperatively. The endothelial cell parameters were analyzed for 6 months.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n The groups were matched for age (\n P<\/jats:italic>\n = 0.467), gender (\n P<\/jats:italic>\n = 0.497), nuclear grade (\n P<\/jats:italic>\n = 0.321), and anterior chamber depth (\n P<\/jats:italic>\n = 0.635). The EPT and EFU were significantly lower in group III, compared to group II and group I, with\n P<\/jats:italic>\n < 0.0001 and\n P<\/jats:italic>\n < 0.0001, respectively. Postoperatively, the endothelial cell density (ECD) was significantly higher in group III at 1 month (\n P<\/jats:italic>\n < 0.0001), 3 months (\n P<\/jats:italic>\n < 0.0001), and 6 months (\n P<\/jats:italic>\n < 0.0001). The percentages of ECD loss were also significantly lower in group III; the difference was statistically significant (\n P<\/jats:italic>\n < 0.0001) up to 6 months postoperatively\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Higher frequency ultrasound was associated with a lower EPT and EFU as well as better endothelial preservation than lower frequencies in hard cataracts.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/ijo.ijo_2163_21","type":"journal-article","created":{"date-parts":[[2022,3,28]],"date-time":"2022-03-28T07:53:23Z","timestamp":1648454003000},"page":"1180-1185","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":14,"title":["Comparison of effective phacoemulsification time and corneal endothelial cell loss using three different ultrasound frequencies: A randomized controlled trial"],"prefix":"10.4103","volume":"70","author":[{"given":"Taru","family":"Dewan","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Atal Bihari Vajpayee Institute of Medical Sciences and Dr Ram Manohar Lohia Hospital, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Praveen K","family":"Malik","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Atal Bihari Vajpayee Institute of Medical Sciences and Dr Ram Manohar Lohia Hospital, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Preeti","family":"Tomar","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Atal Bihari Vajpayee Institute of Medical Sciences and Dr Ram Manohar Lohia Hospital, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,3,22]]},"reference":[{"key":"B1-20240828","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1016\/j.jcrs.2019.04.015","article-title":"Comparison of effective phacoemulsification time and corneal endothelial cell loss using 2 ultrasound frequencies","volume":"45","author":"Dewan","year":"2019","journal-title":"J Cataract Refract Surg"},{"key":"B2-20240828","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1001\/archopht.1993.01090060119035","article-title":"The lens opacities classification system III. 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