{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T20:47:50Z","timestamp":1787863670974,"version":"build-2784847793"},"reference-count":13,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>The aim of this study was to report the outcome of cataract surgery with different surgical techniques in eyes with coexisting coloboma and to define factors of prognostic importance.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Retrospective case sheet review of patients presenting between January 2016 and December 2018, who underwent cataract surgery in eyes with coexisting coloboma.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Of the 3,30,231 cases operated during the study period, 280 eyes of 276 patients had associated colobomatous malformation. The prevalence of coloboma in eyes undergoing cataract surgery was 0.085%. The mean age of the patients was 46.4 years (range 19 - 88 years). Phacoemulsification (PE) was performed in 130 eyes (46.4%), manual small incision cataract surgery (M-SICS) was done in 115 eyes (41.1%), and 35 eyes (12.5%) underwent intra capsular cataract extraction. Intra-operative complications were noted in 26 (9%) eyes. Incidence of intra-operative and post-operative complications was comparable between PE and M-SICS groups (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.94). The mean corrected distance visual acuity (CDVA) improved from logMAR 1.71 \u00b1 0.62 to 0.87 \u00b1 0.61 (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.00009). On multivariate analysis, microcornea (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.002), type 1 and 2 coloboma (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; 0.001), and intraoperative complications (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.001) were associated with poor visual outcome.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Favorable functional outcomes can be achieved with phacoemulsification in eyes with softer cataract and corneal diameter &gt;8 mm and with M-SICS in eyes with hard cataracts and corneal diameter of 6\u20138 mm. PE should be considered as the primary choice whenever permissible by the corneal diameter and severity of nuclear sclerosis. Poor functional outcomes were seen in eyes with smaller corneal diameter, extensive chorioretinal coloboma, and intraoperative complications.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_2276_20","type":"journal-article","created":{"date-parts":[[2021,3,17]],"date-time":"2021-03-17T05:15:35Z","timestamp":1615958135000},"page":"937-945","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":13,"title":["Cataract surgery in eyes with associated coloboma"],"prefix":"10.4103","volume":"69","author":[{"given":"Gaurav","family":"Kohli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chintan","family":"Shah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alok","family":"Sen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajesh","family":"Joshi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Devindra","family":"Sood","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Narendra","family":"Patidar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pradhnya","family":"Sen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Devendra","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanya","family":"Jain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-32-20240828","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/S0039-6257(00)00151-X","article-title":"Ocular colobomata","volume":"45","author":"Onwochei","year":"2000","journal-title":"Surv Ophthalmol"},{"key":"R2-32-20240828","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1016\/S0886-3350(00)00433-8","article-title":"Phacoemulsification and intraocular lens placement in eyes with cataract and congenital coloboma: Visual acuity and complications","volume":"26","author":"Nordlund","year":"2000","journal-title":"J Cataract Refract Surg"},{"key":"R3-32-20240828","doi-asserted-by":"crossref","first-page":"2489","DOI":"10.1007\/s00417-013-2397-1","article-title":"Outcomes of phacoemulsification in eyes with congenital choroidal coloboma","volume":"251","author":"Khokhar","year":"2013","journal-title":"Graefe\u2018s Arch Clin Exp Ophthalmol"},{"key":"R4-32-20240828","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1002\/(SICI)1096-8628(19980217)75:5<497::AID-AJMG8>3.0.CO;2-K","article-title":"Congenital eye malformations: Clinical\u2013epidemiological analysis of 1,124,654 consecutive births in Spain","volume":"75","author":"Bermejo","year":"1998","journal-title":"Am J Med Genet"},{"key":"R5-32-20240828","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1001\/archophthalmol.2010.320","article-title":"Incidence, ocular findings, and systemic associations of ocular coloboma","volume":"129","author":"Nakamura","year":"2011","journal-title":"Arch Ophthalmol"},{"key":"R6-32-20240828","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1016\/S0161-6420(92)31934-7","article-title":"Prevalence of age- related lens opacities in a population; the Beaver Dam Eye Study","volume":"99","author":"Klein","year":"1992","journal-title":"Ophthalmology"},{"key":"R7-32-20240828","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1136\/bjophthalmol-2011-300233","article-title":"Cataract surgery in eyes with congenital iridolenticular choroidal coloboma","volume":"96","author":"Chaurasia","year":"2011","journal-title":"Br J Ophthalmol"},{"key":"R8-32-20240828","first-page":"320","article-title":"Scleral tunnel phacoemulsification: Approach for eyes with severe microcornea","volume":"64","author":"Khokhar","year":"2018","journal-title":"Indian J Ophthalmol"},{"key":"R9-32-20240828","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1016\/j.jcrs.2019.01.016","article-title":"Cataract surgery outcomes in eyes with chorioretinalcoloboma","volume":"45","author":"Sahay","year":"2019","journal-title":"J Cataract Refract Surg"},{"key":"R11-32-20240828","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1001\/archopht.1993.01090060119035","article-title":"The lens opacities classification system III","volume":"111","author":"Chylack","year":"1993","journal-title":"Arch Ophthalmol"},{"key":"R15-32-20240828","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/j.ajo.2005.03.057","article-title":"Standardization of uveitis nomenclature for reporting clinical data. 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