{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T14:59:13Z","timestamp":1792681153478,"version":"4.5.0"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"9","license":[{"start":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T00:00:00Z","timestamp":1756425600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:p>This study aimed to assess the interchangeability of pachymetry measurements obtained by anterior segment optical coherence tomography (AS-OCT) and ultrasound biomicroscopy (UBM) in children with congenital corneal opacity (CCO). In this single-centre, comparative case series, children with unilateral or bilateral CCO who underwent examination under anesthesia (EUA) were evaluated using both AS-OCT and UBM. Pachymetry values from both modalities were compared using Bland\u2013Altman analysis, and topography maps from AS-OCT were examined. A total of 54 eyes from 34 children (16 males, 18 females) were included. The mean age at first EUA was 263.93 \u00b1 348.98 days (range: 11 days to 4 years). Mean pachymetry was 785.83 \u00b1 23 \u03bcm with UBM and 719.80 \u00b1 247 \u03bcm with AS-OCT, showing a statistically significant mean difference of 66.04 \u00b1 133.55 \u03bcm (P = 0.0006). UBM consistently yielded higher measurements, and Bland\u2013Altman analysis indicated poor agreement between the two devices. The findings suggest that AS-OCT and UBM are not interchangeable for pachymetry assessment in CCO. However, AS-OCT, being non-contact and usable without sedation, provides practical advantages for longitudinal follow-up and also offers topographic imaging, making it a useful tool in pediatric corneal evaluation.<\/jats:p>","DOI":"10.4103\/ijo.ijo_242_25","type":"journal-article","created":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T16:01:58Z","timestamp":1756483318000},"page":"1383-1388","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Comparative analysis of pachymetry and assessment of corneal topography in pediatric congenital corneal opacities: A study of AS-OCT and UBM imaging modalities"],"prefix":"10.4103","volume":"73","author":[{"given":"Sonam","family":"Yangzes","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Advanced Eye Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, 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