{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:27:31Z","timestamp":1787758051779,"version":"build-2784847793"},"reference-count":6,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"7","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:p>To the best of the author\u2019s knowledge, bilateral megalopapilla are entities with an unknown inheritance pattern, and this is the first case presentation of bilateral megalopapilla in twin siblings. One of the twins presented to the outpatient department with a frontal headache, while the other was asymptomatic. Upon examination of the first family members, the asymptomatic paternal grandfather had a similar presentation of megalopapilla. As a result, this report will help in determining the genetic pattern of development of this optic disc anomaly, as well as its crucial differential diagnosis.<\/jats:p>","DOI":"10.4103\/ijo.ijo_2480_21","type":"journal-article","created":{"date-parts":[[2022,7,12]],"date-time":"2022-07-12T06:28:32Z","timestamp":1657607312000},"page":"2610-2611","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Case series: Megalopapillae in twins \u2013 Congenital or hereditary?"],"prefix":"10.4103","volume":"70","author":[{"given":"Somya","family":"Sharma","sequence":"first","affiliation":[{"name":"Regional Institute of Ophthalmology, Government Medical College, Amritsar, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karamjit","family":"Singh","sequence":"additional","affiliation":[{"name":"Regional Institute of Ophthalmology, Government Medical College, Amritsar, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prem Pal","family":"Kaur","sequence":"additional","affiliation":[{"name":"Regional Institute of Ophthalmology, Government Medical College, Amritsar, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,6,30]]},"reference":[{"key":"B1-20240828","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/0002-9394(50)90841-5","article-title":"Megalopapilla;a new congenital anomaly","volume":"33","author":"Franceschetti","year":"1950","journal-title":"Am J Ophthalmol"},{"issue":"4","key":"B2-20240828","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1023\/A:1014465522326","article-title":"The pseudoglaucomas","volume":"23","author":"Sampolesi","year":"2001","journal-title":"International Ophthalmology"},{"key":"B3-20240828","article-title":"Megalopailla ;American Academy of Optometry","author":"Jane","year":"2012"},{"key":"B4-20240828","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.survophthal.2006.10.002","article-title":"Optic disc size and glaucoma","volume":"52","author":"Hoffmann","year":"2007","journal-title":"Surv Ophthalmol"},{"key":"B5-20240828","first-page":"4989","article-title":"Pediatric eversional angle closure with headache;A very treatable progressive glaucoma","volume":"59","author":"Sponsel","year":"2018","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"B6-20240828","doi-asserted-by":"crossref","first-page":"e1000978","DOI":"10.1371\/journal.pgen.1000978","article-title":"A genome-wide association study of optic disc parameters","volume":"6","author":"Ramdas","year":"2010","journal-title":"PLoS Genet"}],"container-title":["Indian Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijo.IJO_2480_21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:03:21Z","timestamp":1787756601000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijo.IJO_2480_21"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,30]]},"references-count":6,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4103\/ijo.ijo_2480_21","relation":{},"ISSN":["0301-4738","1998-3689"],"issn-type":[{"value":"0301-4738","type":"print"},{"value":"1998-3689","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,6,30]]},"assertion":[{"value":"2021-10-01","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-02-07","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}