{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:50:09Z","timestamp":1787071809792,"version":"build-2736575974"},"reference-count":26,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","license":[{"start":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T00:00:00Z","timestamp":1765497600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To analyze Bruch\u2019s membrane opening minimum rim width (BMO\u2013MRW) for detecting glaucoma in patients with myopia &lt; \u22126D and assessment of peripapillary retinal nerve fiber layer thickness (pRNFLT).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>One eye was randomly selected from each of the 90 subjects (A-30 normal controls, B-30 with glaucoma suspect, and C-30 with primary open-angle glaucoma [POAG]). All patients underwent baseline ophthalmic evaluation. BMO\u2013 MRW and pRNFLT data were obtained using spectral-domain optical coherence tomography (Spectralis, Heidelberg Engineering GmbH, Heidelberg, Germany). The area under the receiver operating characteristic curves (AUC) for global and sectoral thickness parameters was calculated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Sectoral analysis of BMO-MRW for the discrimination of early glaucoma in all myopic subjects showed significantly better diagnostic performance than pRNFLT in temporal (0.85 (0.77 to 0.94)\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.014), temporal superior (TS) (0.90 (0.83 to 0.98)\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.005), and nasal inferior quadrants (0.92 (0.86 to 0.97)\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.022) with 95% CI. When discriminating early glaucoma from the suspect, overall the diagnostic performance of BMO-MRW was higher than that of pRNFLT, with significant differences in the temperosuperior quadrant (0.85 (0.74 to 0.95) 95% CI,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.047).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>BMO-MRW had better diagnostic performance than RNFL thickness and is a useful parameter for detecting glaucoma in myopic eyes (\u2264\u22126D) with POAG.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_2525_24","type":"journal-article","created":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T17:00:09Z","timestamp":1765558809000},"page":"354-361","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Diagnostic accuracy of Bruch\u2019s membrane opening minimum rim width for detecting glaucoma in Indian myopic eyes"],"prefix":"10.4103","volume":"74","author":[{"given":"Mohideen Abdul","family":"Kader","sequence":"first","affiliation":[{"name":"Department of Glaucoma, Aravind Eye Hospital and PG Institute of Ophthalmology, Tirunelveli, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeyapriya","family":"Thangavel","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, Aravind Eye Hospital and PG Institute of Ophthalmology, Tirunelveli, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madhavi Ramanatha","family":"Pillai","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, Aravind Eye Hospital and PG Institute of Ophthalmology, Tirunelveli, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shivam","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, Aravind Eye Hospital and PG Institute of Ophthalmology, Tirunelveli, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed Sithiq","family":"Uduman","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Aravind Eye Hospital and PG Institute of Ophthalmology, Tirunelveli, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rengappa","family":"Ramakrishnan","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, Aravind Eye Hospital and PG Institute of Ophthalmology, Tirunelveli, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,12,12]]},"reference":[{"key":"R1-20260417","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1038\/519276a","article-title":"The myopia boom","volume":"519","author":"Dolgin","year":"2015","journal-title":"Nature"},{"key":"R2-20260417","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1016\/j.ophtha.2016.01.006","article-title":"Global prevalence of myopia and high myopia and temporal trends from 2000 through 2050","volume":"123","author":"Holden","year":"2016","journal-title":"Ophthalmology"},{"key":"R3-20260417","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.ophtha.2006.06.050","article-title":"High Myopia and glaucoma susceptibility the Beijing eye study","volume":"114","author":"Xu","year":"2007","journal-title":"Ophthalmology"},{"key":"R4-20260417","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1016\/j.ajo.2006.05.022","article-title":"Comparison of optic disk and retinal nerve fiber layer thickness in nonglaucomatous and glaucomatous patients with high myopia","volume":"142","author":"Melo","year":"2006","journal-title":"Am J Ophthalmol"},{"key":"R5-20260417","doi-asserted-by":"crossref","first-page":"e86417","DOI":"10.1371\/journal.pone.0086417","article-title":"Glaucoma-induced optic disc morphometric changes and glaucoma diagnostic ability of Heidelberg Retina Tomograph II in highly myopic eyes","volume":"9","author":"Mayama","year":"2014","journal-title":"PLoS One"},{"key":"R6-20260417","doi-asserted-by":"crossref","first-page":"1843","DOI":"10.1007\/s00417-012-1994-8","article-title":"Impact of high myopia on the performance of SD-OCT parameters to detect glaucoma","volume":"250","author":"Shoji","year":"2012","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"R7-20260417","first-page":"NC01","article-title":"Optical coherence tomography assisted retinal nerve fibre layer thickness profile in high myopia","volume":"9","author":"Malakar","year":"2015","journal-title":"J Clin Diagn Res"},{"key":"R8-20260417","doi-asserted-by":"crossref","first-page":"335","DOI":"10.3341\/kjo.2016.30.5.335","article-title":"Influence of myopia on size of optic nerve head and retinal nerve fiber layer thickness measured by spectral domain optical coherence tomography","volume":"30","author":"Bae","year":"2016","journal-title":"Korean J Ophthalmol"},{"key":"R9-20260417","doi-asserted-by":"crossref","first-page":"1852","DOI":"10.1167\/iovs.11-9309","article-title":"Influence of clinically invisible, but optical coherence tomography detected, optic disc margin anatomy on neuroretinal rim evaluation","volume":"53","author":"Reis","year":"2012","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"R10-20260417","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/j.ophtha.2012.09.055","article-title":"Enhanced detection of open-angle glaucoma with an anatomically accurate optical coherence tomography-derived neuroretinal rim parameter","volume":"120","author":"Chauhan","year":"2013","journal-title":"Ophthalmology"},{"key":"R11-20260417","doi-asserted-by":"crossref","first-page":"540-9.e1","DOI":"10.1016\/j.ajo.2013.11.007","article-title":"A method to estimate the amount of neuroretinal rim tissue in glaucoma: Comparison with current methods for measuring rim area","volume":"157","author":"Gardiner","year":"2014","journal-title":"Am J Ophthalmol"},{"key":"R12-20260417","doi-asserted-by":"crossref","first-page":"2953","DOI":"10.1167\/iovs.13-13482","article-title":"Structure-function relationships with spectral-domain optical coherence tomography retinal nerve fiber layer and optic nerve head measurements","volume":"55","author":"Pollet-Villard","year":"2014","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"R13-20260417","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1016\/j.ophtha.2016.01.052","article-title":"Diagnostic accuracy of optical coherence tomography and scanning laser tomography for identifying glaucoma in myopic eyes","volume":"123","author":"Malik","year":"2016","journal-title":"Ophthalmology"},{"key":"R14-20260417","doi-asserted-by":"crossref","first-page":"4106","DOI":"10.1167\/iovs.17-22057","article-title":"Determinants and characteristics of Bruch\u2019s membrane opening and Bruch\u2019s membrane opening-minimum rim width in a normal Japanese population","volume":"58","author":"Araie","year":"2017","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"R15-20260417","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.3390\/jcm8091362","article-title":"Characteristics of patients showing discrepancy between Bruch\u2019s membrane opening-minimum rim width and peripapillary retinal nerve fiber layer thickness","volume":"8","author":"Cho","year":"2019","journal-title":"J Clin Med"},{"key":"R16-20260417","doi-asserted-by":"crossref","first-page":"2417","DOI":"10.2147\/OPTH.S120237","article-title":"The new Bruch\u2019s membrane opening-minimum rim width classification improves optical coherence tomography specificity in tilted discs","volume":"10","author":"Rebolleda","year":"2016","journal-title":"Clin Ophthalmol"},{"key":"R17-20260417","doi-asserted-by":"crossref","first-page":"42","DOI":"10.5301\/ejo.5001022","article-title":"Utility of Bruch membrane opening-based optic nerve head parameters in myopic subjects","volume":"28","author":"Sastre-Iba\u00f1ez","year":"2018","journal-title":"Eur J Ophthalmol"},{"key":"R18-20260417","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1097\/IJG.0000000000001934","article-title":"Clinical utility of Bruch membrane opening-minimum rim width for detecting early glaucoma in myopic eyes","volume":"30","author":"Park","year":"2021","journal-title":"J Glaucoma"},{"key":"R19-20260417","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1007\/s00347-017-0616-6","article-title":"[Bruch\u2019s membrane opening minimum rim width: Correlation and diagnostic accuracy in comparison to peripapillary retinal nerve fiber layer thickness]","volume":"116","author":"Awe","year":"2019","journal-title":"Ophthalmologe"},{"key":"R20-20260417","doi-asserted-by":"crossref","first-page":"19564","DOI":"10.1038\/s41598-019-55926-w","article-title":"Bruch\u2019s membrane opening enlargement and its implication on the myopic optic nerve head","volume":"9","author":"Sung","year":"2019","journal-title":"Sci Rep"},{"key":"R21-20260417","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.ogla.2019.11.008","article-title":"A comparison of OCT parameters in identifying glaucoma damage in eyes suspected of having glaucoma","volume":"3","author":"Stagg","year":"2020","journal-title":"Ophthalmol Glaucoma"},{"key":"R22-20260417","first-page":"575","article-title":"Comparison of Bruch\u2019s membrane opening minimum rim width and peripapillary retinal nerve fiber layer thickness in early glaucoma assessment","volume":"201657","author":"Gmeiner","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"R23-20260417","doi-asserted-by":"crossref","first-page":"729523","DOI":"10.3389\/fmed.2021.729523","article-title":"Diagnostic classification of Bruch\u2019s membrane opening-minimum rim width and retinal nerve fiber layer thickness in myopic eyes by optical coherence tomography","volume":"8","author":"Wang","year":"2021","journal-title":"Front Med (Lausanne)"},{"key":"R24-20260417","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1097\/IJG.0000000000001571","article-title":"A topographic comparison of OCT minimum rim width (BMO\u2013MRW) and circumpapillary retinal nerve fiber layer (cRNFL) thickness measures in eyes with or suspected glaucoma","volume":"29","author":"La Bruna","year":"2020","journal-title":"J Glaucoma"},{"key":"R25-20260417","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1007\/BF02169209","article-title":"Optic disk morphometry in high myopia","volume":"226","author":"Jonas","year":"1988","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"R26-20260417","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1007\/BF00946938","article-title":"Optic disc morphology in myopic primary open-angle glaucoma","volume":"235","author":"Jonas","year":"1997","journal-title":"Graefes Arch Clin Exp Ophthalmol"}],"container-title":["Indian Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/IJO.IJO_2525_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:56:35Z","timestamp":1787068595000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/IJO.IJO_2525_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,12]]},"references-count":26,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/ijo.ijo_2525_24","relation":{},"ISSN":["0301-4738","1998-3689"],"issn-type":[{"value":"0301-4738","type":"print"},{"value":"1998-3689","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,12]]},"assertion":[{"value":"2024-10-22","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-27","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}