{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T02:35:11Z","timestamp":1787279711512,"version":"build-2736575974"},"reference-count":22,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","license":[{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To study the long-term microvasculature changes at the macula and the optic disk in eyes with nonarteritic anterior ischemic optic neuropathy (NAION).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Patients with acute NAION of less than 6 weeks duration were included. Optical coherence tomography angiography (OCTA) of the macula and the optic disk was performed at baseline, 3 and 6 months and compared with the controls.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The mean age of 15 patients was 52.25 (\u00b19.06) years. The whole image superficial peripapillary density (42.49 \u00b1 5.28) was significantly low when compared to that of control eyes (46.36 \u00b1 2.09); similarly, radial peripapillary capillary density (49.35 \u00b1 5.64) was also significantly reduced when compared to controls (53.45 \u00b1 1.96,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05). These parameters showed significant progressive decrease at 3 and 6 months (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05). At the macula, both superficial (41.83 \u00b1 3.64) and deep macular vasculature densities (47.30 \u00b1 2.04) were significantly reduced when compared to control eyes (52.15 \u00b1 4.84 and 55.13 \u00b1 1.81, respectively). The vascular density at the macula remained stable at 3- and 6-months period.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The study shows that the microvasculature in case of NAION is significantly reduced both in peripapillary area and in macular area.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_2537_22","type":"journal-article","created":{"date-parts":[[2023,5,17]],"date-time":"2023-05-17T03:01:20Z","timestamp":1684292480000},"page":"2020-2026","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":8,"title":["Evaluation of optical coherence tomography angiography changes in nonarteritic anterior ischemic optic neuropathy"],"prefix":"10.4103","volume":"71","author":[{"given":"Swati","family":"Phuljhele","sequence":"first","affiliation":[{"name":"Neuro-ophthalmology and Strabismus Services, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sumant","family":"Sharma","sequence":"additional","affiliation":[{"name":"Neuro-ophthalmology and Strabismus Services, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rohan","family":"Chawla","sequence":"additional","affiliation":[{"name":"Retina Services, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rohit","family":"Saxena","sequence":"additional","affiliation":[{"name":"Neuro-ophthalmology and Strabismus Services, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pradeep","family":"Sharma","sequence":"additional","affiliation":[{"name":"Neuro-ophthalmology and Strabismus Services, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,5,17]]},"reference":[{"key":"R1-20251006","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1001\/archopht.1985.01050080048018","article-title":"The risk of cerebrovascular and cardiovascular disease in patients with anterior ischemic optic neuropathy","volume":"103","author":"Guyer","year":"1985","journal-title":"Arch Ophthalmol"},{"key":"R2-20251006","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1136\/bjo.58.12.955","article-title":"Anterior ischaemic optic neuropathy. 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