{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T07:50:24Z","timestamp":1791359424643,"version":"4.3.1"},"reference-count":22,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"10","license":[{"start":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:00:00Z","timestamp":1790640000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To evaluate the short-term safety and efficacy of slow-coagulation trans-scleral cyclophotocoagulation (SC-TSCPC) in patients with refractory glaucoma.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A retrospective study was done on 140 patients (144 eyes) with a diagnosis of refractory glaucoma and vision more than 2\/60 with a minimum follow-up of 6 months. All patients underwent SC-TSCPC (800-milliwatt power and 4 seconds duration). The primary outcome measure was surgical success defined as an intraocular pressure (IOP) from 6 to 21 mmHg or \u226520% IOP reduction from the baseline value, no reoperation for glaucoma, and no loss of light perception vision. Secondary outcome measures include percentage of IOP reduction, glaucoma medications, visual acuity, and complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Mean IOP decreased from 40.97 \u00b1 12.00 mmHg preoperatively to 19.31 \u00b1 9.91 mmHg (mean percentage IOP reduction = 52.9%) at 6 months postoperatively (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.0001). The number of glaucoma medications also dropped from 3.0 \u00b1 0.89 at baseline to 2.0 \u00b1 1.4 at 6 months (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.0003). No significant deterioration in visual acuity was observed during 6 months follow-up (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.0001). The cumulative probabilities of success at 1, 3, and 6 months were 86.1%, 77.4%, and 66.64%, respectively. Eyes with baseline IOP &gt;30 mmHg demonstrated lower success rates, higher postoperative complications, and greater need for additional glaucoma interventions compared with eyes having baseline IOP &lt;30 mmHg. The most common complications observed were uncontrolled IOP and anterior chamber inflammation. Endophthalmitis and retinal detachment were seen in one patient at 6-month follow-up.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>SC-TSCPC may serve as a useful adjunct or temporizing procedure in selected refractory glaucoma patients who are at high risk for invasive glaucoma surgery. Patients with high preoperative IOP required more surgical interventions and also had more complications warranting individualized laser energy settings.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_2553_25","type":"journal-article","created":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T14:03:54Z","timestamp":1790690634000},"page":"1518-1524","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Clinical outcomes of slow-coagulation continuous wave diode transscleral cyclophotocoagulation laser for treatment of refractory glaucoma"],"prefix":"10.4103","volume":"74","author":[{"given":"Vijayalakshmi A","family":"Senthilkumar","sequence":"first","affiliation":[{"name":"Department of Glaucoma, Aravind Eye Hospital and Postgraduate Institute of Ophthalmology, Madurai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabari","family":"Jagadesh","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, Aravind Eye Hospital and Research Institute, Madurai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"Anto","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, Aravind Eye Hospital and Research Institute, Madurai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iswarya","family":"Mani","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Aravind Eye Hospital and Research Institute, Madurai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharmila","family":"Rajendrababu","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, Aravind Eye Hospital and Research Institute, Madurai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,9,29]]},"reference":[{"key":"R1-20261007","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1136\/bjo.2005.081224","article-title":"The number of people with glaucoma worldwide in 2010 and 2020","volume":"90","author":"Quigley","year":"2006","journal-title":"Br J Ophthalmol"},{"key":"R2-20261007","doi-asserted-by":"crossref","first-page":"e879","DOI":"10.1097\/IJG.0000000000000490","article-title":"Additive effect of risk factors for trabeculectomy failure in glaucoma patients: A risk-group from a cohort study","volume":"25","author":"Issa","year":"2016","journal-title":"J Glaucoma"},{"key":"R3-20261007","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1097\/00004397-198102110-00012","article-title":"Cyclocryotherapy for glaucoma","volume":"21","author":"Bellows","year":"1981","journal-title":"Int Ophthalmol Clin"},{"key":"R4-20261007","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1016\/S0161-6420(96)30508-3","article-title":"Long-term outcome of initial ciliary ablation with contact diode laser transscleral cyclophotocoagulation for severe glaucoma. 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