{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T20:29:37Z","timestamp":1786739377300,"version":"build-2736575974"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 2","license":[{"start":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T00:00:00Z","timestamp":1779235200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To evaluate wound healing after cyanoacrylate glue patch (CGP) application in corneal perforations using anterior segment optical coherence tomography (ASOCT).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>Prospective interventional case series.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Twenty-eight patients with corneal perforations (&lt;4 mm) underwent CGP application. The primary outcome measure was wound healing pattern on ASOCT after CGP application. Secondary outcomes were time to removal of CGP and anatomical success. Follow-up was performed on POD 1 and every 2 weeks till CGP removal.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Three distinct wound healing patterns were observed on ASOCT: Type 1 with corrugated hyper-reflective mass corresponding to CGP with underlying shadowing, Type 2 pattern with ongoing stromal regeneration without continuity with surrounding healthy cornea, and Type 3 with complete stromal regeneration beneath the CGP continuous with surrounding cornea. On POD 1, 100% cases had type 1 pattern. At 2 weeks, 85.7% had type 2; 14.3% had type 1 pattern. At 4 weeks, 35.7% cases had type 3 and 64.3% had type 2 pattern. Five cases underwent early glue removal (type 2 pattern) at 31.8 \u00b1 2.5 days because of CGP intolerance; of these, 40% (2\/5) developed a leak and required reapplication of CGP. Total 82.1% cases achieved type 3 pattern by 8 weeks. CGP was removed after documentation of type 3 pattern in 82.1% cases at 41.7 \u00b1 9.2 days; no case developed wound leak.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>ASOCT is a useful adjunct to objectively monitor wound healing after CGP and guide regarding optimal timing for its removal, with type 3 pattern correlating with higher anatomical success.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_2612_25","type":"journal-article","created":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T10:00:19Z","timestamp":1779357619000},"page":"S203-S208","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Anterior segment optical coherence tomography-guided assessment of wound healing after cyanoacrylate glue patch for corneal perforations"],"prefix":"10.4103","volume":"74","author":[{"given":"Manpreet","family":"Kaur","sequence":"first","affiliation":[{"name":"Cornea, Cataract and Refractive Surgery Services, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vaibhav","family":"Namdev","sequence":"additional","affiliation":[{"name":"Cornea, Cataract and Refractive Surgery Services, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silpa","family":"Lalu","sequence":"additional","affiliation":[{"name":"Cornea, Cataract and Refractive Surgery Services, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarath 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