{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,15]],"date-time":"2026-08-15T18:40:03Z","timestamp":1786819203637,"version":"build-2736575974"},"reference-count":32,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"9","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To observe the trends of various types of keratoplasties in different etiologies over a period of 10 years (2011-2020) in a tertiary eye care center of eastern India.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A retrospective review of patients undergoing keratoplasties from 2011 to 2020 was performed in a tertiary eye care hospital situated in eastern part of India. Apart from demographic data, primary indication for each surgery and type of procedure carried out was recorded. For comparison, data were divided into two time periods: Group I: Jan 2011 to Dec 2015 and Group II: Jan 2016 to Dec 2020.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Over a period of 10 years, a total of 2365 (Group I: 902, Group II: 1463) keratoplasties were performed. The average age of patients was 45.8 \u00b1 19.9 and 46.9 \u00b1 20.9 years in Group I and Group II, respectively. Among all the corneal grafts, 1747 (74%) surgeries were full-thickness. Although optical penetrating keratoplasty (OPK) was most the common indication for full-thickness keratoplasties, Descemet\u2019s stripping endothelial keratoplasty (DSEK) remained most performed lamellar keratoplasty. Keratitis, corneal scars, and bullous keratopathies remain to be most common indications in both groups. Number of lamellar keratoplasties increased significantly from Group I to Group II for corneal scars (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.02), bullous keratopathies (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.01), and endothelial dystrophies (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.00).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>With change in time, the indication and technique of keratoplasty has witnessed a changing trend from full-thickness keratoplasty to lamellar keratoplasty. There is rise in trend of lamellar keratoplasties over the period.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_2636_22","type":"journal-article","created":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T07:55:43Z","timestamp":1692604543000},"page":"3166-3170","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":5,"title":["Indications and types of keratoplasties: Trends in the past 10 years (2011-2020) in Eastern India"],"prefix":"10.4103","volume":"71","author":[{"given":"Amanjot","family":"Kaur","sequence":"first","affiliation":[{"name":"Cornea and Anterior Segment Service, L V Prasad Eye Institute, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priyadarsani","family":"Parida","sequence":"additional","affiliation":[{"name":"Cornea and Anterior Segment Service, L V Prasad Eye Institute, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Smruti Rekha","family":"Priyadarshini","sequence":"additional","affiliation":[{"name":"Cornea and Anterior Segment Service, L V Prasad Eye Institute, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amrita","family":"Mohanty","sequence":"additional","affiliation":[{"name":"Cornea and Anterior Segment Service, L V Prasad Eye Institute, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Srikant K","family":"Sahu","sequence":"additional","affiliation":[{"name":"Cornea and Anterior Segment Service, L V Prasad Eye Institute, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sujata","family":"Das","sequence":"additional","affiliation":[{"name":"Cornea and Anterior Segment Service, L V Prasad Eye Institute, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,8,21]]},"reference":[{"key":"R1-20251008","doi-asserted-by":"crossref","first-page":"198","DOI":"10.4103\/0970-0218.120153","article-title":"Burden of corneal blindness in India","volume":"38","author":"Gupta","year":"2013","journal-title":"Indian J Community Med"},{"key":"R2-20251008","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1136\/bjo.87.2.133","article-title":"Corneal blindness in a southern Indian population:Need for health promotion strategies","volume":"87","author":"Dandona","year":"2003","journal-title":"Br J Ophthalmol"},{"key":"R3-20251008","first-page":"47","article-title":"Perspectives in eye banking","volume":"44","author":"Saini","year":"1996","journal-title":"Indian J Ophthalmol"},{"key":"R4-20251008","doi-asserted-by":"crossref","first-page":"423","DOI":"10.4103\/0301-4738.100540","article-title":"Turning the tide of corneal blindness","volume":"60","author":"Oliva","year":"2012","journal-title":"Indian J Ophthalmol"},{"key":"R5-20251008","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1007\/BF01949227","article-title":"Eine erfolgreiche totale Keratoplastik","volume":"64","author":"Zirm","year":"1906","journal-title":"Graefes Arch Ophthalmol"},{"key":"R6-20251008","first-page":"509","article-title":"A new era in corneal transplantation:Paradigm shift and evolution of techniques","volume":"18","author":"Young","year":"2012","journal-title":"Hong Kong Med J"},{"key":"R7-20251008","doi-asserted-by":"crossref","first-page":"332","DOI":"10.47102\/annals-acadmedsg.V38N4p332","article-title":"Paradigm shifts in corneal transplantation","volume":"38","author":"Tan","year":"2009","journal-title":"Ann Acad Med Singap"},{"key":"R8-20251008","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.4103\/ijo.IJO_95_18","article-title":"Lamellar keratoplasty techniques","volume":"66","author":"Singh","year":"2018","journal-title":"Indian J Ophthalmol"},{"key":"R9-20251008","first-page":"214","article-title":"Corneal blindness:A global perspective","volume":"79","author":"Whitcher","year":"2001","journal-title":"Bull World Health Organ"},{"key":"R10-20251008","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1177\/1120672118762224","article-title":"Corneal transplantation trends in France from 2004 to 2015:A 12-year review","volume":"28","author":"Bigan","year":"2018","journal-title":"Eur J Ophthalmol"},{"key":"R11-20251008","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1001\/archophthalmol.2011.2585","article-title":"Trends in the indications for corneal graft surgery in the United Kingdom:1999 through 2009","volume":"130","author":"Keenan","year":"2012","journal-title":"Arch Ophthalmol"},{"key":"R12-20251008","first-page":"379","article-title":"Indications for and techniques of keratoplasty at Vietnam National Institute of Ophthalmology","volume":"9","author":"Dong","year":"2016","journal-title":"Int J Ophthalmol"},{"key":"R13-20251008","first-page":"NC01","article-title":"Indications and visual outcome of penetrating keratoplasty in tertiary eye care institute in Uttarakhand","volume":"10","author":"Raj","year":"2016","journal-title":"J Clin Diagn Res"},{"key":"R14-20251008","first-page":"163","article-title":"Indications for penetrating keratoplasty in India","volume":"45","author":"Dandona","year":"1997","journal-title":"Indian J Ophthalmol"},{"key":"R15-20251008","first-page":"2505","article-title":"Indications of penetrating keratoplasty in southern India","volume":"7","author":"Dasar","year":"2013","journal-title":"J Clin Diagn Res"},{"key":"R16-20251008","article-title":"Keratoplasty in the United States:Trends and Indications From 2015 to 2020","author":"Xiao","journal-title":"Cornea 2022. Epub ahead of print"},{"key":"R17-20251008","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1007\/s11845-020-02340-1","article-title":"Changing trends in corneal transplantation:A national review of current practices in the Republic of Ireland","volume":"190","author":"Iselin","year":"2021","journal-title":"Ir J Med Sci"},{"key":"R18-20251008","doi-asserted-by":"crossref","first-page":"2432","DOI":"10.1016\/j.ophtha.2015.08.017","article-title":"Keratoplasty in the United States:A 10-year review from 2005 through 2014","volume":"122","author":"Park","year":"2015","journal-title":"Ophthalmology"},{"key":"R19-20251008","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1016\/j.jcjo.2018.02.023","article-title":"New trends in corneal transplants at the University of Toronto","volume":"53","author":"Chan","year":"2018","journal-title":"Can J Ophthalmol"},{"key":"R20-20251008","doi-asserted-by":"crossref","first-page":"207","DOI":"10.3126\/nepjoph.v5i2.8730","article-title":"Indications for keratoplasty in Nepal:2005-2010","volume":"5","author":"Bajracharya","year":"2013","journal-title":"Nepal J Ophthalmol"},{"key":"R21-20251008","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1111\/j.1442-9071.2011.02598.x","article-title":"Indications and outcomes of penetrating keratoplasty in a tertiary hospital in the developing world","volume":"40","author":"Pan","year":"2012","journal-title":"Clin Exp Ophthalmol"},{"key":"R22-20251008","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1097\/ICO.0b013e31825694d3","article-title":"Seasonal trends of microbial keratitis in South India","volume":"31","author":"Lin","year":"2012","journal-title":"Cornea"},{"key":"R23-20251008","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1097\/01.ico.0000157406.34662.0f","article-title":"Indications of penetrating keratoplasty in northern India","volume":"24","author":"Sony","year":"2005","journal-title":"Cornea"},{"key":"R24-20251008","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/S0886-3350(01)01181-6","article-title":"Big-bubble technique to bare Descemet's membrane in anterior lamellar keratoplasty","volume":"28","author":"Anwar","year":"2002","journal-title":"J Cataract Refract Surg"},{"key":"R25-20251008","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1097\/ICO.0000000000000066","article-title":"Evolving indications for and trends in keratoplasty in British Columbia, Canada, from 2002 to 2011:A 10-year review","volume":"33","author":"Tan","year":"2014","journal-title":"Cornea"},{"key":"R26-20251008","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/S0002-9394(02)02278-X","article-title":"Assessment of visual function after corneal transplantation:The quality of life and psychometric assessment after corneal transplantation (Q-PACT) study","volume":"135","author":"Mendes","year":"2003","journal-title":"Am J Ophthalmol"},{"key":"R27-20251008","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1080\/02713683.2020.1849727","article-title":"Macular corneal dystrophy:An updated review","volume":"46","author":"Singh","year":"2021","journal-title":"Curr Eye Res"},{"key":"R28-20251008","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1136\/bjophthalmol-2011-300244","article-title":"Changing trends in keratoplasty in the West of Scotland:A 10-year review","volume":"96","author":"Ting","year":"2012","journal-title":"Br J Ophthalmol"},{"key":"R29-20251008","first-page":"387","article-title":"Eleven years of corneal transplantation (1992\u20132003) at the Semmelweis University 1st Department of Ophthalmology","volume":"141","author":"Szentm\u00e1ry","year":"2004","journal-title":"Szem\u00e9szet"},{"key":"R30-20251008","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1097\/ICO.0000000000000538","article-title":"Visual recovery and endothelial cell survival after Descemet stripping automated endothelial keratoplasty for failed penetrating keratoplasty grafts\u2014A cohort study","volume":"34","author":"Tarantino-Scherrer","year":"2015","journal-title":"Cornea"},{"key":"R31-20251008","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1006\/exer.1997.0410","article-title":"Induction of cross-links in corneal tissue","volume":"66","author":"Spoerl","year":"1998","journal-title":"Exp Eye Res"},{"key":"R32-20251008","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1097\/01.ico.0000159730.45177.cd","article-title":"Outcomes of penetrating keratoplasty in keratoconus","volume":"24","author":"Javadi","year":"2005","journal-title":"Cornea"}],"container-title":["Indian Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/IJO.IJO_2636_22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:42:14Z","timestamp":1786650134000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/IJO.IJO_2636_22"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,21]]},"references-count":32,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.4103\/ijo.ijo_2636_22","relation":{},"ISSN":["0301-4738","1998-3689"],"issn-type":[{"value":"0301-4738","type":"print"},{"value":"1998-3689","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,8,21]]},"assertion":[{"value":"2022-10-09","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-07-04","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}