{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T03:55:32Z","timestamp":1792814132077,"version":"4.5.0"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To assess the safety and efficacy of transzonular moxifloxacin and dexamethasone versus standard postoperative topical drug regimen in phacoemulsification.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>Nonrandomized prospective study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>The study included 100 eyes of 100 age and gender-matched individuals with senile cataract undergoing routine phacoemulsification. The patients were consecutively divided into transzonular (TZ = 50) and topical (TP = 50) groups. Both the groups were followed up for 4 weeks and assessed for intraocular inflammation, visual acuity, changes in intraocular pressure (IOP), and any adverse events.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The grades of inflammation were significantly lower in TZ as compared to the TP group (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001). The IOP remained normal and comparable in both the groups. Most of the patients in the two groups attained a visual acuity of 0.2 or better at the end of the follow-up. No adverse effects and increased rate of endophthalmitis were noted in TZ group.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>A one-time peroperative TZ moxifloxacin and dexamethasone combination is a safe and effective method to control postoperative inflammation after cataract surgery. A word of caution though, due precautions to be exercised to prevent the risk of inflammation and endophthalmitis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_2697_23","type":"journal-article","created":{"date-parts":[[2024,5,20]],"date-time":"2024-05-20T11:01:53Z","timestamp":1716202913000},"page":"1147-1149","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":4,"title":["Transzonular moxifloxacin and dexamethasone delivery in phacoemulsification: A novel dropless regimen"],"prefix":"10.4103","volume":"72","author":[{"given":"M Srinivasan","family":"Gounder","sequence":"first","affiliation":[{"name":"Institute of Ophthalmology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Syed W A","family":"Rizvi","sequence":"additional","affiliation":[{"name":"Institute of Ophthalmology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Humayoun","family":"Asharaf","sequence":"additional","affiliation":[{"name":"Institute of Ophthalmology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adeeb A","family":"Khan","sequence":"additional","affiliation":[{"name":"Institute of Ophthalmology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sameer","family":"Ashraf","sequence":"additional","affiliation":[{"name":"Institute of Ophthalmology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Afeefa","family":"Akhtar","sequence":"additional","affiliation":[{"name":"Institute 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Ocul Pharmacol Ther"},{"key":"R10-20260507","doi-asserted-by":"crossref","first-page":"345","DOI":"10.2147\/OPTH.S5730","article-title":"Intracameral dexamethasone reduces inflammation on the first postoperative day after cataract surgery in eyes with and without glaucoma","volume":"3","author":"Chang","year":"2009","journal-title":"Clin Ophthalmol"},{"key":"R11-20260507","doi-asserted-by":"crossref","first-page":"1670","DOI":"10.1016\/j.jcrs.2005.07.023","article-title":"Effect of intracameral triamcinolone to control inflammation following cataract surgery","volume":"31","author":"Gills","year":"2005","journal-title":"J Cataract Refract Surg"}],"container-title":["Indian Journal of 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