{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T16:42:22Z","timestamp":1786725742551,"version":"build-2736575974"},"reference-count":22,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>This study aimed to determine the clinical indications for orbital exenteration, demographic profile of these patients, and clinicopathologic correlations in the current times and to compare these results with previous published data.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>It was a retrospective study. All exenterations performed at a tertiary eye care center over a period of 20 years (from January 2001 to June 2020) were retrospectively evaluated. Patient records were reviewed to obtain demographic data, presenting symptoms and their duration, laterality, and clinical and histopathologic diagnosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      A total of 352 cases (males:females = 222:130) who underwent exenteration were identified. Patients age ranged from 11 months to 87 years (mean: 43.86 years, median: 50 years). The most common indication for exenteration was found to be eyelid malignancy in 54.36%, followed by retinoblastoma in 18.75% and primary orbital tumors in 14.49%. Out of 156 cases of eyelid malignancies requiring exenteration, squamous cell carcinoma (SCC) was the most common histologic subtype (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 94, 60.26%), followed by sebaceous gland carcinoma (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 40, 25.64%) and basal cell carcinoma (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 20, 12.82%). The most common primary orbital tumors requiring exenteration were adenocystic carcinoma of the lacrimal gland in adults and rhabdomyosarcoma in the pediatric age group. Benign conditions requiring exenteration included fulminant fungal orbital infections and lymphangioma among others.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The number of exenterations performed have significantly increased in terms of absolute numbers. However, the ratio of exenteration to other tumor-related surgeries, mainly excision biopsy, has reduced compared to that reported from a previous study. The most common indication in our study remains eyelid malignancy followed by intraocular malignancy. However, SCC has emerged as the most common tumor histologic subtype requiring exenterations.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_2716_23","type":"journal-article","created":{"date-parts":[[2024,3,8]],"date-time":"2024-03-08T04:02:47Z","timestamp":1709870567000},"page":"S610-S615","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Clinicodemographic profile of orbital exenteration in a tertiary eye care center \u2013 A 20-year experience"],"prefix":"10.4103","volume":"72","author":[{"given":"Rachna","family":"Meel","sequence":"first","affiliation":[{"name":"Oculoplasty and Oncology Services, AIIMS, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neelam","family":"Pushker","sequence":"additional","affiliation":[{"name":"Oculoplasty and Oncology Services, AIIMS, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seema","family":"Kashyap","sequence":"additional","affiliation":[{"name":"Department of Ocular Pathology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, AIIMS, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shweta","family":"Chaurasia","sequence":"additional","affiliation":[{"name":"Oculoplasty and Oncology Services, AIIMS, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aishwarya","family":"Rathod","sequence":"additional","affiliation":[{"name":"Oculoplasty and Oncology Services, AIIMS, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mandeep Singh","family":"Bajaj","sequence":"additional","affiliation":[{"name":"Oculoplasty and Oncology Services, AIIMS, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seema","family":"Sen","sequence":"additional","affiliation":[{"name":"Department of Ocular Pathology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, AIIMS, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sahil","family":"Agrawal","sequence":"additional","affiliation":[{"name":"Oculoplasty and Oncology Services, AIIMS, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,3,8]]},"reference":[{"key":"R2-20260507","first-page":"208.","volume":"3","author":"Bartisch","year":"1583","journal-title":"Ophthalmodoulcia, Dresden"},{"key":"R3-20260507","first-page":"413","article-title":"Orbito-sinus exenteration","volume":"141","author":"Golovine","year":"1909","journal-title":"Ann Ocul"},{"key":"R4-20260507","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1080\/08164622.2022.2106781","article-title":"Psychosocial factors among patients undergoing orbital exenteration","volume":"106","author":"Balakrishnan","year":"2023","journal-title":"Clin Exp Optom"},{"key":"R5-20260507","first-page":"292","article-title":"Orbital exenteration with eyelid sparing: Indications, technique, and results","volume":"22","author":"Shields","year":"1991","journal-title":"Ophthalmic Surg"},{"key":"R6-20260507","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1007\/BF01401757","article-title":"Repair after orbital exenteration. 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