{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T17:27:20Z","timestamp":1786728440973,"version":"build-2736575974"},"reference-count":33,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"11","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To determine the demographic and microbiological profile involved in the causation of corneal ulcers in Eastern India during the COVID era.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method:<\/jats:title>\n                    <jats:p>Patients presenting with corneal ulcers fulfilling the inclusion and exclusion criteria were taken as the case. The study duration was from January 2021 to December 2021. Socio-demographic details and information about risk factors were noted. A detailed corneal examination followed by corneal scraping was performed for microbiological evaluation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      In 1 year, 99 infective corneal ulcer patients were evaluated. Farmers (24.2%) were found to be maximally affected by corneal ulcers. The peak in cases was recorded from October to December (38.4%). Ocular trauma was the commonest risk factor (42.4%). The majority (80.8%) of patients were already on some topical antimicrobials. 22.2% of samples showed fungal filaments on KOH mount; 54.5% of these cases turned out to be culture-positive. 17.56% of KOH-negative samples turned out to be culture-positive (fungal). Overall, the culture positivity rate was 28.28% out of which fungal isolates were 89.28% and bacterial isolates were 10.72%.\n                      <jats:italic toggle=\"yes\">Fusarium<\/jats:italic>\n                      species were identified as the most common organism contributing 42.85%, followed by\n                      <jats:italic toggle=\"yes\">Aspergillus fumigatus<\/jats:italic>\n                      (14.28%). 10.72% of cases were culture positive for\n                      <jats:italic toggle=\"yes\">Pseudomonas aeuroginosa.<\/jats:italic>\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>\n                      Trauma with the organic matter was the predominant cause of fungal keratitis. In this study, fungal keratitis was found to be more common.\n                      <jats:italic toggle=\"yes\">Fusarium<\/jats:italic>\n                      was the most common isolate.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_2752_22","type":"journal-article","created":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T11:17:36Z","timestamp":1697800656000},"page":"3522-3527","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Demographic and microbiological profile of corneal ulcer patients presenting at a tertiary healthcare center of Eastern India during the COVID era: A hospital-based cross-sectional study"],"prefix":"10.4103","volume":"71","author":[{"given":"Naila","family":"Aftab","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, All India Institute of Medical Sciences (AIIMS), Patna, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amit","family":"Raj","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, All India Institute of Medical Sciences (AIIMS), Patna, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bhawesh","family":"Chandra","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, All India Institute of Medical Sciences (AIIMS), Patna, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Binod Kumar","family":"Pati","sequence":"additional","affiliation":[{"name":"Department of Microbiology, All India Institute of Medical Sciences (AIIMS), Patna, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prabhakar","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, All India Institute of Medical Sciences (AIIMS), Patna, 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