{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T07:50:33Z","timestamp":1791359433026,"version":"4.3.1"},"reference-count":22,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"10","license":[{"start":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:00:00Z","timestamp":1790640000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To evaluate the diagnostic yield of Humphrey visual field (HVF) 30-2 automated perimetry in differentiating neurological from non-neurological causes of visual dysfunction.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Design: Retrospective observational record-based study. Setting: Department of Ophthalmology at a tertiary-care referral institute in Central India. Study population: All HVF tests performed between July 2023 and June 2025 were reviewed. Of 1,438 tests performed, 383 reliable HVF tests using the 30-2 program with the Swedish Interactive Threshold Algorithm (SITA) Standard or SITA Fast strategy were included. Tests with fixation losses &gt;20%, false positive or negative responses &gt;15%, incomplete records, or media opacities were excluded. Observation procedure: Visual field tests were categorized according to indication as neurological or non-neurological causes. Field patterns were analyzed and correlated with clinical findings and neuroimaging results. Main outcome measure: The primary outcome was diagnostic yield, defined as the proportion of HVF (30-2 program) contributing to confirmation of neurological disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Among 383 HVF 30-2 tests, 226 (59.0%) were performed for neurological indications. Abnormal fields were detected in 132\/226 (58.4%) neurological cases compared with 42\/157 (26.8%) non-neurological cases (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001; odds ratio [OR] 3.84; 95% confidence interval [CI]: 2.48\u20135.95). Confirmed neurological diseases were identified in 118 (52.2%) neurological referrals versus 3 (1.9%) non-neurological referrals (OR 56.6; 95% CI: 17.4\u2013184.0). Bitemporal hemianopia (23.5%), homonymous hemianopia (19.7%), and central scotoma (16.7%) were the most common field patterns, with &gt;90% radiological correlation. HVF 30-2 testing demonstrated high diagnostic performance for neurological disorders (OR 56.6; 95% CI: 17.4\u2013184.0;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>HVF 30-2 perimetry demonstrates high diagnostic yield for neurological disorders and serves as a reliable, noninvasive functional investigation for neuro-ophthalmic evaluation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_2767_25","type":"journal-article","created":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T14:04:18Z","timestamp":1790690658000},"page":"1503-1508","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Diagnostic yield of Humphrey visual field 30-2 testing for neurological versus non-neurological visual disorders: A tertiary-care retrospective study"],"prefix":"10.4103","volume":"74","author":[{"given":"Priti","family":"Singh","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, All India Institute of Medical Sciences (AIIMS), Bhopal, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samendra","family":"Karkhur","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, All India Institute of Medical Sciences (AIIMS), Bhopal, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vidhya","family":"Verma","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, All India Institute of Medical Sciences (AIIMS), Bhopal, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saroj","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, All India Institute of Medical Sciences (AIIMS), Bhopal, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rama Tulasi Siri","family":"Duddumpudi","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, All India Institute of Medical Sciences (AIIMS), Bhopal, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,9,29]]},"reference":[{"key":"R1-20261007","doi-asserted-by":"crossref","first-page":"e606","DOI":"10.1097\/WNO.0000000000001157","article-title":"Introducing the 24-2C visual field test in neuro-ophthalmology","volume":"41","author":"Yamane","year":"2021","journal-title":"J Neuroophthalmol"},{"key":"R2-20261007","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/s11910-024-01332-3","article-title":"Interpretation of the visual field in neuro-ophthalmic disorders","volume":"24","author":"Banc","year":"2024","journal-title":"Curr Neurol Neurosci 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