{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T18:59:53Z","timestamp":1791226793109,"version":"4.1.0"},"reference-count":23,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,1]]},"abstract":"\n Purpose:<\/jats:title>\n We aimed to investigate hemodynamic changes in the retina, peripapillary area, and choroid in patients undergoing coronary artery bypass grafting (CABG).<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n This prospective case series included 35 eyes of 35 patients. Vessel density (VD) of superficial capillary plexus, deep capillary plexus, radial peripapillary capillary, foveal avascular zone area, and subfoveal choroidal thickness changes were evaluated using optical coherence tomography angiography (OCTA) 1 day before and 2 weeks after surgery. The correlation of these parameters with aortic cross-clamp (ACC) duration and cardiopulmonary bypass (CPB) duration was evaluated.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n There were no differences in the OCTA measurements of the patients after CABG compared to before surgery (\n P<\/jats:italic>\n > 0.05). Inside-disc VD showed a negative correlation with both ACC (\n P<\/jats:italic>\n = 0.036) and CPB duration (\n P<\/jats:italic>\n = 0.048); peripapillary inferior hernia showed a negative correlation with both ACC (\n P<\/jats:italic>\n = 0.042) and CPB duration (\n P<\/jats:italic>\n = 0.027). Another negative correlation was observed between mean peripapillary VD and CPB duration (\n P<\/jats:italic>\n = 0.039).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n The CPB procedure had no permanent effect on retinal choroid and optic disc blood flow postoperatively. Prolonged ACC and CPB times seem to be important in terms of optic nerve blood flow. Clinicians should be alert for postoperative ocular complications after long surgeries.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/ijo.ijo_2800_22","type":"journal-article","created":{"date-parts":[[2023,12,22]],"date-time":"2023-12-22T01:03:15Z","timestamp":1703206995000},"page":"S119-S124","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":6,"title":["Evaluation of retinal and peripapillary vessel density and subfoveal choroidal thickness changes in patients undergoing cardiopulmonary bypass: An OCTA study"],"prefix":"10.4103","volume":"72","author":[{"given":"G\u00f6ksu Hande Naz","family":"\u015eimdivar","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, University of Health Sciences Adana City Training and Research Hospital, Adana, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tu\u011fba Kurumo\u011flu","family":"\u0130ncekalan","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University of Health Sciences Adana City Training and Research Hospital, Adana, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akif","family":"G\u00fcnd\u00fcz","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, University of Health Sciences Adana City Training and Research Hospital, Adana, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,12,22]]},"reference":[{"key":"R1-20260508","doi-asserted-by":"crossref","first-page":"87","DOI":"10.3109\/17453059009055108","article-title":"Demonstration of cerebral microemboli occurring during coronary artery bypass graft surgery using fluorescein angiography","volume":"13","author":"Arnold","year":"1990","journal-title":"J Audiov Media Med"},{"key":"R2-20260508","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1007\/s00540-010-0983-5","article-title":"Changes in intraocular pressure during cardiac surgery with and without cardiopulmonary bypass","volume":"24","author":"Hayashi","year":"2010","journal-title":"J Anesth"},{"key":"R3-20260508","doi-asserted-by":"crossref","first-page":"1410","DOI":"10.1097\/00000539-200112000-00012","article-title":"Risk factors for ischemic optic neuropathy after cardiopulmonary bypass: A matched case\/control study","volume":"93","author":"Nuttall","year":"2001","journal-title":"Anesth Analg"},{"key":"R4-20260508","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1212\/WNL.32.5.560","article-title":"Ischemic optic neuropathy: A complication of cardiopulmonary bypass surgery","volume":"32","author":"Sweeney","year":"1982","journal-title":"Neurology"},{"key":"R5-20260508","doi-asserted-by":"crossref","first-page":"e168","DOI":"10.1111\/j.1755-3768.2011.02317.x","article-title":"Vision impairment during cardiac surgery and extracorporeal circulation: Current understanding and the need for further investigation","volume":"90","author":"Nenekidis","year":"2012","journal-title":"Acta Ophthalmol"},{"key":"R6-20260508","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1016\/S0140-6736(86)92871-0","article-title":"Retinal microembolism during cardiopulmonary bypass demonstrated by fluorescein angiography","volume":"328","author":"Blauth","year":"1986","journal-title":"Lancet"},{"key":"R7-20260508","first-page":"85","article-title":"The effects of platelet aggregates on the retinal microcirculation","volume":"9","author":"Paterson","year":"1967","journal-title":"Bibl Anat"},{"key":"R8-20260508","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1038\/eye.2017.181","article-title":"An overview of the clinical applications of optical coherence tomography angiography","volume":"32","author":"Tan","year":"2018","journal-title":"Eye (Lond)"},{"key":"R9-20260508","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/s40942-015-0005-8","article-title":"A review of optical coherence tomography angiography (OCTA)","volume":"1","author":"de Carlo","year":"2015","journal-title":"Int J Retina Vitreous"},{"key":"R10-20260508","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.preteyeres.2017.07.002","article-title":"Optical coherence tomography angiography: A comprehensive review of current methods and clinical applications","volume":"60","author":"Kashani","year":"2017","journal-title":"Prog Retin Eye Res"},{"key":"R11-20260508","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1136\/bjophthalmol-2016-308764","article-title":"Repeatability of automated vessel density measurements using optical coherence tomography angiography","volume":"101","author":"Al-Sheikh","year":"2017","journal-title":"Br J Ophthalmol"},{"key":"R12-20260508","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.1364\/BOE.10.001532","article-title":"Retinal and choroidal vascular changes in coronary heart disease: An optical coherence tomography angiography study","volume":"10","author":"Wang","year":"2019","journal-title":"Biomed Opt Express"},{"key":"R13-20260508","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1093\/eurheartj\/eht023","article-title":"The eye and the heart","volume":"34","author":"Flammer","year":"2013","journal-title":"Eur Heart J"},{"key":"R14-20260508","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1016\/j.amjcard.2004.07.135","article-title":"Extramural coronary arteries in adults with cyanotic congenital heart disease","volume":"94","author":"Chugh","year":"2004","journal-title":"Am J Cardiol"},{"key":"R15-20260508","doi-asserted-by":"crossref","first-page":"E14","DOI":"10.1111\/j.1747-0803.2011.00586.x","article-title":"Headache and papilledema in an adult with cyanotic congenital heart disease: The importance of fundoscopic evaluation rather than phlebotomy","volume":"7","author":"Loomba","year":"2012","journal-title":"Congenit Heart Dis"},{"key":"R16-20260508","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1038\/sj.eye.6701408","article-title":"Ocular pathology in congenital heart disease","volume":"19","author":"Mansour","year":"2005","journal-title":"Eye (Lond)"},{"key":"R17-20260508","doi-asserted-by":"crossref","first-page":"1394","DOI":"10.1213\/ane.0b013e3181875e2e","article-title":"Optimal perfusion during cardiopulmonary bypass: An evidence-based approach","volume":"108","author":"Murphy","year":"2009","journal-title":"Anesth Analg"},{"key":"R18-20260508","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1007\/BF00946937","article-title":"Autoregulation of human optic nerve head blood flow in response to acute changes in ocular perfusion pressure","volume":"235","author":"Riva","year":"1997","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"R19-20260508","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1186\/1749-8090-6-154","article-title":"A case report and brief review of the literature on bilateral retinal infarction following cardiopulmonary bypass for coronary artery bypass grafting","volume":"6","author":"Trethowan","year":"2011","journal-title":"J Cardiothorac Surg"},{"key":"R20-20260508","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1177\/0267659114529324","article-title":"Choroidal changes after cardiopulmonary bypass","volume":"29","author":"Pekel","year":"2014","journal-title":"Perfusion"},{"key":"R21-20260508","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1510\/icvts.2010.260950","article-title":"Blood flow measurements within optic nerve head during on-pump cardiovascular operations. A window to the brain?","volume":"12","author":"Nenekidis","year":"2011","journal-title":"Interact Cardiovasc Thorac Surg"},{"key":"R22-20260508","first-page":"354","article-title":"Anterior ischemic optic neuropathy: A complication after extracorporal circulation","volume":"4","author":"Busch","year":"1998","journal-title":"Ann Thorac Cardiovasc Surg"},{"key":"R23-20260508","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.preteyeres.2008.11.002","article-title":"Ischemic optic neuropathy","volume":"28","author":"Hayreh","year":"2009","journal-title":"Prog Retin Eye Res"}],"container-title":["Indian Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/IJO.IJO_2800_22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T16:27:42Z","timestamp":1786724862000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/IJO.IJO_2800_22"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,22]]},"references-count":23,"journal-issue":{"issue":"Suppl 1","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/ijo.ijo_2800_22","relation":{},"ISSN":["0301-4738","1998-3689"],"issn-type":[{"value":"0301-4738","type":"print"},{"value":"1998-3689","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12,22]]},"assertion":[{"value":"2022-10-24","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-09-22","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}