{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:57:59Z","timestamp":1787169479457,"version":"build-2736575974"},"reference-count":37,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"10","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To evaluate the cost, safety, surgical outcome, and efficacy of modified Cutler\u2013Beard eyelid reconstruction utilizing a novel silicone plate as a tarsal plate replacement in the repair of 60% to 100% eyelid defects following the excision of large malignant tumors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A prospective, noncomparative, interventional study of 30 eyes was done over 3 years. Fourteen patients were female, and 16 patients were male. In all the cases, a silicone plate, the synthetic, artificial tarsal plate, was utilized for a total or subtotal replacement of the tarsal plate. The created defect was measured in mm (length and width) and later expressed in percentage. Pre- and postoperative action of levator palpebrae superioris (LPS) was measured. Pre- and postoperative measurements of the margin-to-margin reflex distance (MRD1) were noted.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Preoperative LPS action was 1.23 \u00b1 1.35 mm, whereas postoperative LPS actions at the end of 1 week and 18 months were 11. 8 \u00b1 0.88 mm and 13.53 \u00b1 0. 73 mm, respectively. Preoperative MRD1 was \u2212 3.0 \u00b1 1.144 mm, whereas postoperative MRD1 values at the end of 1 week and 18 months were 2.18 \u00b1 0.27 mm and 4.16 mm \u00b1 0.35, respectively. The mean created defect after the removal of the tumor was 87.3% \u00b111.10. The mean length of the silicone plate implanted in this study was 27.53 \u00b1 2.48 mm. The follow-up period for the study participants was 18 months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The synthetic novel silicone plate was successful as a tarsal plate replacement. A second surgical site for ear cartilage harvesting is avoided. Cadaver transfer of Achilles tendon carries the risk of transmission of communicable diseases, for example, hepatitis B and HIV. Silicone is an inert, nonreacting, and tissue-tested material, thus eliminating the possibility of graft rejection. This material is readily available and cost-effective. The novel silicone plate is considered to be the most promising alternative material as a tarsal replacement in the future generation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_2822_20","type":"journal-article","created":{"date-parts":[[2021,10,5]],"date-time":"2021-10-05T11:42:39Z","timestamp":1633434159000},"page":"2788-2795","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":5,"title":["Total or subtotal replacement of tarsal plate by novel silicone plate for upper eyelid reconstruction in malignant tumors"],"prefix":"10.4103","volume":"69","author":[{"given":"Salil Kumar","family":"Mandal","sequence":"first","affiliation":[{"name":"Regional Institute of Ophthalmology, Medical College of Calcutta, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Basupurna","family":"Majumdar","sequence":"additional","affiliation":[{"name":"Regional Institute of 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