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Both anatomical and structural properties of cornea and anterior chamber contribute toward its immune tolerance. Clinically, every layer of the transplanted cornea can get a rejection episode. A proper understanding of immunopathogenesis will help in understanding the various mechanism of CGR and the development of newer strategies for the prevention and management of such cases.<\/jats:p>","DOI":"10.4103\/ijo.ijo_2866_22","type":"journal-article","created":{"date-parts":[[2023,5,17]],"date-time":"2023-05-17T03:26:13Z","timestamp":1684293973000},"page":"1733-1738","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":24,"title":["Immunopathogenesis of corneal graft rejection"],"prefix":"10.4103","volume":"71","author":[{"given":"Prafulla Kumar","family":"Maharana","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sohini","family":"Mandal","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Dr. 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