{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:20:55Z","timestamp":1787761255424,"version":"build-2784847793"},"reference-count":3,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"9","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:p>\n                    A 51-year-old immunocompetent male with a history of Fuchs' endothelial dystrophy and immature cataract who underwent Descemet's stripping automated endothelial keratoplasty with intraocular lens implantation in both eyes presented with redness and defective vision of 1-day duration in his left eye. Slit lamp examination revealed coarse superficial punctate lesions with graft edema. He was diagnosed with acute graft rejection and treated with topical steroids. Two days later, symptoms worsened in his left eye with the involvement of his right eye showing a similar clinical picture. An infectious etiology was suspected and\n                    <jats:italic toggle=\"yes\">in vivo<\/jats:italic>\n                    confocal microscopy ordered, which revealed hyperreflective dots, highly suggestive of microsporidial spores. The patient was prescribed topical fluconazole 0.3% in both eyes. This unique presentation of bilateral graft edema following microsporidial keratoconjunctivitis in postgraft patients requires a high index of suspicion as it can be easily be mistaken for and mismanaged as acute graft rejection.\n                  <\/jats:p>","DOI":"10.4103\/ijo.ijo_295_17","type":"journal-article","created":{"date-parts":[[2017,9,18]],"date-time":"2017-09-18T23:17:01Z","timestamp":1505776621000},"page":"869-871","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":4,"title":["Microsporidial infection masquerading as graft rejection post-Descemet's stripping automated endothelial keratoplasty"],"prefix":"10.4103","volume":"65","author":[{"given":"Lumbini","family":"Devi","sequence":"first","affiliation":[{"name":"Department of Cornea, Aravind Eye Hospital, Madurai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N Venkatesh","family":"Prajna","sequence":"additional","affiliation":[{"name":"Department of Cornea, Aravind Eye Hospital, Madurai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muthiah","family":"Srinivasan","sequence":"additional","affiliation":[{"name":"Department of Cornea, Aravind Eye Hospital, Madurai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naveen","family":"Radhakrishnan","sequence":"additional","affiliation":[{"name":"Department of Cornea, Aravind Eye Hospital, Madurai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manoranjan","family":"Das","sequence":"additional","affiliation":[{"name":"Department of Cornea, Aravind Eye Hospital, Madurai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20251013","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1038\/sj.eye.6702178","article-title":"Microsporidia keratoconjunctivitis in a corneal graft","volume":"20","author":"Kakrania","year":"2006","journal-title":"Eye (Lond)"},{"key":"R2-20251013","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1097\/ICO.0000000000000337","article-title":"Microsporidial stromal keratitis masquerading as acute graft rejection","volume":"34","author":"Pradhan","year":"2015","journal-title":"Cornea"},{"key":"R3-20251013","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1097\/ICO.0b013e31806c7a3c","article-title":"Microsporidium stromal keratitis: In vivo confocal findings","volume":"26","author":"Sagoo","year":"2007","journal-title":"Cornea"}],"container-title":["Indian Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/02223307-201765090-00019","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:29:51Z","timestamp":1787758191000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/02223307-201765090-00019"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9]]},"references-count":3,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2017]]}},"URL":"https:\/\/doi.org\/10.4103\/ijo.ijo_295_17","relation":{},"ISSN":["0301-4738","1998-3689"],"issn-type":[{"value":"0301-4738","type":"print"},{"value":"1998-3689","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,9]]},"assertion":[{"value":"2017-04-18","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-07-06","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}