{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T10:24:12Z","timestamp":1788258252863,"version":"build-2803163510"},"reference-count":28,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>Angle-based surgeries for the treatment of open-angle glaucoma have gained popularity in recent years. This study aimed to evaluate the efficacy of combined phacoemulsification and goniotomy in primary open-angle and pseudoexfoliation glaucoma (POAG and PXG) and ocular hypertension (OHTN).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>In this interventional case series in the setting of the Glaucoma Service at the Farabi Eye Hospital, 32 eyes of 30 patients with early-to-moderate POAG and PXG and OHTN were enrolled. All eyes underwent combined phacoemulsification and needle goniotomy. Intraocular pressure (IOP) and the number of antiglaucoma medications as well as demographic data were recorded at baseline and one day, one week, one month, three months, and six months after the surgery. Generalized Estimating Equation (GEE) was used to compare the values of IOP and the number of medications at different time points. Kaplan\u2013Meier graph was used to demonstrate the survival status of the eyes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Mean IOP at baseline was 21.8 \u00b1 4.6 mmHg on mean 1.2 \u00b1 1.5 topical medications. There was a 25.2% (16.3 \u00b1 4.5 mmHg) and 32.1% (14.8 \u00b1 3.9 mmHg) reduction in IOP at three and six months after procedure, respectively (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001). Meanwhile, the decline in medications was 66.7% (0.4 \u00b1 0.9) and 50.0% (0.6 \u00b1 1.1) at the same time points (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.002 and\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.048, respectively). Post-operative complications were clot hyphema (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 1, 3.1%), fibrinous inflammation (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 1, 3.1%) and distorted pupil (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 2, 6.3%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Combined phacoemulsification and needle goniotomy as a procedure for mild and moderate POAG and PXG and OHTN is as effective as other modified goniotomies in the setting of minimally invasive glaucoma surgeries (MIGS).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_2969_21","type":"journal-article","created":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T07:18:21Z","timestamp":1654067901000},"page":"2030-2035","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":11,"title":["Six-month outcomes of combined conventional needle goniotomy and phacoemulsification in eyes with early to moderate primary open-angle and pseudoexfoliation glaucoma and ocular hypertension"],"prefix":"10.4103","volume":"70","author":[{"given":"Yadollah","family":"Eslami","sequence":"first","affiliation":[{"name":"Glaucoma Service, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massood","family":"Mohammadi","sequence":"additional","affiliation":[{"name":"Glaucoma Service, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mona","family":"Safizadeh","sequence":"additional","affiliation":[{"name":"Glaucoma Service, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seyed Mehdi","family":"Tabatabaei","sequence":"additional","affiliation":[{"name":"Glaucoma Service, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,5,31]]},"reference":[{"key":"R1-20251004","doi-asserted-by":"crossref","first-page":"2081","DOI":"10.1016\/j.ophtha.2014.05.013","article-title":"Global prevalence of glaucoma and projections of glaucoma burden through 2040:A systematic review and meta-analysis","volume":"121","author":"Tham","year":"2014","journal-title":"Ophthalmology"},{"issue":"Suppl 1","key":"R2-20251004","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1016\/j.survophthal.2008.08.006","article-title":"Risk factors for glaucoma onset and progression","volume":"53","author":"Coleman","year":"2008","journal-title":"Surv Ophthalmol"},{"key":"R3-20251004","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/j.exer.2005.10.011","article-title":"What controls aqueous humour outflow resistance?","volume":"82","author":"Johnson","year":"2006","journal-title":"Exp Eye Res"},{"key":"R4-20251004","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/0002-9394(68)91288-9","article-title":"Trabeculectomy. 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combined with excisional goniotomy using the Kahook Dual Blade in severe glaucoma patients at 6 months","volume":"13","author":"Hirabayashi","year":"2019","journal-title":"Clin Ophthalmol Auckl NZ"},{"key":"R21-20251004","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1097\/01.ijg.0000196653.77836.af","article-title":"Ab interno trabeculectomy:Development of a novel device (Trabectome) and surgery for open-angle glaucoma","volume":"15","author":"Francis","year":"2006","journal-title":"J Glaucoma"},{"key":"R22-20251004","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1016\/j.jcrs.2008.03.032","article-title":"Combined cataract extraction and trabeculotomy by the internal approach for coexisting cataract and open-angle glaucoma:Initial results","volume":"34","author":"Francis","year":"2008","journal-title":"J Cataract Refract Surg"},{"key":"R23-20251004","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1016\/j.ajo.2013.06.001","article-title":"Clinical 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