{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:32:23Z","timestamp":1787761943861,"version":"build-2784847793"},"reference-count":52,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To study the effect of increasing grades of hypertensive retinopathy (HTR) on neonatal outcomes among preeclamptic women and assess the various maternal risk factors for HTR.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A prospective cohort study was conducted on 258 preeclamptic women. The systolic and diastolic blood pressure (SBP and DBP), liver, and renal function parameters were collected besides basic demographic details. Dilated fundus examination with the Keith\u2013Wagner\u2013Barker classification was used to grade HTR. Following delivery, neonatal outcomes were evaluated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Of the 258 preeclamptic women recruited, 53.1% had preeclampsia (PE), and 46.9% had severe preeclampsia. With increasing grades of HTR, a significant association with low birth weight (LBW) (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.012) and preterm gestational age (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.002) was noted but not with the Appearance, Pulse, Grimace, Activity and Respiration (APGAR) score (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.062). Also, it did not increase the risk of retinopathy of prematurity (ROP), with most babies, even those born to mothers with high grades of HTR, showing no evidence of ROP (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.025). Among the maternal factors, increasing age (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.016), SBP (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; 0.001), DBP (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; 0.001), serum creatinine (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.035), alanine aminotransferase (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.008), lower hemoglobin (Hb) (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.009), lower platelet (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; 0.001), and severe PE (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; 0.001) have been found to significantly affect the grade of HTR.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Higher grades of HTR in the preeclamptic mother are associated with preterm delivery and LBW of the neonates but neither affect the APGAR score nor pose the risk of developing ROP.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_2995_22","type":"journal-article","created":{"date-parts":[[2023,3,8]],"date-time":"2023-03-08T06:19:36Z","timestamp":1678256376000},"page":"910-915","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Correlation between hypertensive retinopathy and fetal outcomes in patients with preeclampsia in a tertiary care hospital: A prospective cohort 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