{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T01:06:02Z","timestamp":1790730362265,"version":"4.1.0"},"reference-count":34,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 2","license":[{"start":{"date-parts":[[2024,8,14]],"date-time":"2024-08-14T00:00:00Z","timestamp":1723593600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To study the early postoperative efficacy and safety of 5-0 Prolene gonioscopy-assisted transluminal trabeculotomy (GATT) combined with phacoemulsification in Indian eyes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      This was a prospective, interventional study. Patients with primary and secondary glaucoma who underwent GATT combined with phacoemulsification (Phaco-GATT) or standalone GATT were included. All patients were evaluated on postoperative days 1, 15, and 30, as well as 3 months and 6 months postoperatively. Baseline and follow-up visits were compared to determine the significant difference in the number of intraocular pressure (IOP), antiglaucoma medications (AGM), and best corrected visual acuity (BCVA). Other outcome measures included surgical success, complications, and interventions. A\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      value of &lt; 0.05 was considered statistically significant.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      One hundred and five eyes (95 patients) were included. Seventy-five eyes underwent GATT along with phacoemulsification and 30 eyes underwent GATT. In the Phaco-GATT group, the mean IOP reduced significantly from 17.71 \u00b1 6.85 to 12.29 \u00b1 4.44, 12.33 \u00b1 4.44, and 12.18 \u00b1 3.49 mmHg and in the GATT group, it reduced from 21.67 \u00b1 11.42 mmHg to 16.38 \u00b1 8.42, 16.47 \u00b1 10.26, and 13.10 \u00b1 3.25 mmHg at 1, 3, and 6 months, respectively (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001). The number of AGM also significantly reduced from 1.67 \u00b1 1.22 to 0.41 \u00b1 0.87 and 0.34 \u00b1 0.82 in the phaco-GATT group and from 2.63 \u00b1 1.19 to 0.67 \u00b1 1.09 and 0.60 \u00b1 1.25 in the GATT group at 3 and 6 months, respectively (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001). Complete success (IOP &gt; 6\u2013\u226421 mmHg\/20% reduction without AGM) was 96.7% in the Phaco-GATT group and 91.2% in the GATT group. BCVA improved from log of minimum angle of resolution 0.30 to 0.00 (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001) in phaco-GATT group. Hyphema was the most common complication. Macrohyphema (&gt;1 mm) was seen in six patients, out of which two patients required anterior chamber wash. IOP spikes (&gt;30 mmHg) were seen in three patients.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>In Indian eyes, GATT combined with phacoemulsification and standalone GATT are efficacious and safe with good surgical outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_3065_23","type":"journal-article","created":{"date-parts":[[2024,8,14]],"date-time":"2024-08-14T13:00:09Z","timestamp":1723640409000},"page":"S287-S292","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":16,"title":["Early outcomes of 5-0 Prolene gonioscopy-assisted transluminal trabeculotomy combined with phacoemulsification in eyes of Indian glaucoma patients"],"prefix":"10.4103","volume":"73","author":[{"given":"Devendra","family":"Maheshwari","sequence":"first","affiliation":[{"name":"Department of Glaucoma, Aravind Eye Hospital and PG Institute of Ophthalmology, Tirunelveli, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madhavi Ramanatha","family":"Pillai","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, Aravind Eye Hospital and PG Institute of Ophthalmology, Tirunelveli, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nimrita Gyanchand","family":"Nagdev","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, Aravind Eye Hospital and PG Institute of Ophthalmology, Tirunelveli, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shivam","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, Aravind Eye Hospital and PG Institute of Ophthalmology, Tirunelveli, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rengappa","family":"Ramakrishnan","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, Aravind Eye Hospital and PG Institute of Ophthalmology, Tirunelveli, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohideen Abdul","family":"Kader","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, Aravind Eye Hospital and PG Institute of Ophthalmology, Tirunelveli, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed Sithiq","family":"Uduman","sequence":"additional","affiliation":[{"name":"Department of Biostatistician, Aravind Eye Hospital and PG Institute of Ophthalmology, Tirunelveli, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,8,14]]},"reference":[{"key":"R1-20250221","doi-asserted-by":"crossref","first-page":"e0024","DOI":"10.5041\/RMMJ.10345","article-title":"Evolution of glaucoma surgery in the last 25 years","volume":"9","author":"Bar-David","year":"2018","journal-title":"Rambam Maimonides Med J"},{"key":"R2-20250221","first-page":"13","article-title":"Minimally invasive glaucoma surgery - 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