{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T10:18:07Z","timestamp":1793787487326,"version":"4.6.1"},"reference-count":13,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"9","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>The aim of this study was to report the incidence of presumed steroid response in contralateral eye of patients who underwent glaucoma filtration surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We reviewed records of 298 glaucoma patients (147 PACG [primary angle-closure glaucoma], 129 POAG [primary open-angle glaucoma], and 22 JOAG [juvenile open-angle glaucoma]) who underwent either trabeculectomy alone or trabeculectomy with cataract extraction. All patients received prednisolone acetate 1% eye drop postoperatively in the operated eye for up to 6 to 8 weeks. The contralateral eye received the same antiglaucoma medications as before. Information collected included age, sex, number of antiglaucoma medications in the fellow eye preoperatively, and VFI (visual field index). The preoperative intraocular pressure (IOP) in the contralateral eye was taken as the baseline. The maximum IOP recorded postoperatively up to a follow-up period of 6 to 8 weeks was noted. A steroid response was defined as rise in the IOP by \u22656 mmHg.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>In this study, 298 eyes of 298 glaucoma patients were included. The mean age of patients was 60.1 \u00b1 13.7 years. The mean number of antiglaucoma medications in the fellow eye pre-operatively was 2.4 \u00b1 1.2. Mean preoperative and postoperative IOP in the fellow eye were 17.46 \u00b1 7 and 19.37 \u00b1 7.1 mmHg, respectively. Sixty-three eyes out of 298 eyes (21.14%) showed a rise in IOP by 6 mmHg. The maximum IOP difference noted was 15 mmHg. The average time interval to the defined steroid response was 16.13 days. The majority showed a steroid response within 19 days.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Steroid response is a significant factor leading to elevated IOP postoperatively in the contralateral eye as well.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_3069_20","type":"journal-article","created":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T23:07:16Z","timestamp":1630537636000},"page":"2481-2483","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":4,"title":["Incidence of presumed steroid response in contralateral eye of patients who underwent glaucoma filtration surgery"],"prefix":"10.4103","volume":"69","author":[{"given":"Rinal","family":"Pandit","sequence":"first","affiliation":[{"name":"Department of Glaucoma, Sankara Nethralaya, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronnie J","family":"George","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, Sankara Nethralaya, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vijaya","family":"Lingam","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, Sankara Nethralaya, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shantha","family":"Balekudaru","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, Sankara Nethralaya, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2021,8,25]]},"reference":[{"key":"B1-20240828","doi-asserted-by":"crossref","first-page":"1753","DOI":"10.1016\/S0161-6420(95)30797-X","article-title":"A ten-year follow-up on a prospective, randomized trial of postoperative corticosteroids after trabeculectomy","volume":"102","author":"Araujo","year":"1995","journal-title":"Ophthalmology"},{"key":"B2-20240828","first-page":"293","article-title":"Use of ACTH and cortisone","volume":"48","author":"McLean","year":"1950","journal-title":"Trans Am Ophthalmol Soc"},{"key":"B3-20240828","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1001\/archopht.1963.00960050017005","article-title":"Steroid-induced elevation of intraocular pressure","volume":"70","author":"Bernstein","year":"1963","journal-title":"Arch Ophthalmol"},{"key":"B4-20240828","first-page":"641","article-title":"Modification exp\u00e9rimentales de l'ophtalmotonous. 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