{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T14:53:30Z","timestamp":1791212010783,"version":"4.1.0"},"reference-count":15,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 3","license":[{"start":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T00:00:00Z","timestamp":1787529600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>\n                      To evaluate the influence of additional ablation (Abl-max) on higher-order aberrations (HOAs), particularly corneal coma, following Phorcides-planned topography-guided laser\n                      <jats:italic toggle=\"yes\">in situ<\/jats:italic>\n                      keratomileusis (LASIK) in an Indian population.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We analyzed 161 eyes of 83 patients undergoing Phorcides-planned topography-guided LASIK between June 2022 and June 2023. Assessments at baseline and 1, 3, and 6 months included distance visual acuity, manifest refraction, Pentacam tomography, and iTrace aberrometry. Abl-Max was stratified into quartiles (Q1-4) and deciles (Q1-10). The primary outcomes were total HOAs and corneal coma (KCm) at 6 months. Logistic, linear, and decision tree regression models identified predictors of low coma (lowest quartile of KCm6 \u2264 0.037m).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Q1 of Abl-max eyes had higher baseline myopia (\u20134.36 \u00b1 1.62D vs. \u20132.76 \u00b1 1.79D), and fewer were treated with 6.5 mm Optic Zone (OZ) (31.2% vs. 67.6%) compared to Q4 (both\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001). At 6 months, KCm6 was higher in Q1 (0.11 \u00b1 0.10 vs. 0.07 \u00b1 0.06 \u00b5m in Q4,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.015). The mean postoperative binocular uncorrected vision was 20\/17 in both quartiles. Logistic regression showed that lower myopia (OR 1.51, 95% CI 1.21\u20131.92;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.0004) and 6.5 mm OZ (OR 4.24, 95% CI 0.92\u201320.38;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.066) predicted low coma. A decision tree model achieved AUROC 0.77, with the lowest coma in eyes with mild-moderate myopia (-2D to -3D) and 6.5 mm OZ.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Phorcides-planned LASIK permits safe deeper ablations with excellent vision, but coma induction persists, especially in higher myopes (&gt;-4D) with 6.0 mm OZ. Larger OZs (6.5 mm) may optimize coma outcomes where residual stromal thickness permits.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_3110_25","type":"journal-article","created":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T07:00:13Z","timestamp":1787554813000},"page":"S410-S416","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Outcomes of higher-order aberration correction in relation to optical zone size after Phorcides-planned laser in situ keratomileusis in Indian Eyes"],"prefix":"10.4103","volume":"74","author":[{"given":"Tanvi","family":"Haldipurkar","sequence":"first","affiliation":[{"name":"Department of Cataract and Refractive Surgery, Laxmi Eye Hospital and Institute, Panvel, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mayuri","family":"Phatak","sequence":"additional","affiliation":[{"name":"Department of Cataract and Refractive Surgery, Laxmi Eye Hospital and Institute, Panvel, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seema","family":"Bhosale","sequence":"additional","affiliation":[{"name":"Department of Cataract and Refractive Surgery, Laxmi Eye Hospital and Institute, Panvel, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u2060Suhas","family":"Haldipurkar","sequence":"additional","affiliation":[{"name":"Department of Cataract and Refractive Surgery, Laxmi Eye Hospital and Institute, Panvel, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hetal","family":"Shah","sequence":"additional","affiliation":[{"name":"Department of Cataract and Refractive Surgery, Laxmi Eye Hospital and Institute, Panvel, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u2060Sarita","family":"Deshpande","sequence":"additional","affiliation":[{"name":"Department of Cataract and Refractive Surgery, Laxmi Eye Hospital and Institute, Panvel, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u2060\u2060Sabyasachi","family":"Sengupta","sequence":"additional","affiliation":[{"name":"Department of Cataract and Refractive Surgery, Laxmi Eye Hospital and Institute, Panvel, Maharashtra, India"},{"name":"Department of Vitreoretina, Future Vision Eye Care, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,8,24]]},"reference":[{"key":"R1-20261005","doi-asserted-by":"crossref","first-page":"527","DOI":"10.3928\/1081597X-20180607-02","article-title":"Wavefront-guided LASIK has comparable ocular and corneal aberrometric outcomes but better visual acuity outcomes than SMILE in myopic eyes","volume":"34","author":"Shetty","year":"2018","journal-title":"J Refract Surg"},{"key":"R2-20261005","doi-asserted-by":"crossref","first-page":"777","DOI":"10.3928\/1081597X-20141021-10","article-title":"Comparative evaluation of higher-order aberrations and corneal asphericity between wavefront-guided and aspheric LASIK for myopia","volume":"30","author":"Goyal","year":"2014","journal-title":"J Refract Surg"},{"key":"R3-20261005","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1097\/ICO.0000000000000707","article-title":"Clinical outcomes after SMILE and femtosecond laser-assisted LASIK for myopia and myopic astigmatism: A prospective randomized comparative study","volume":"35","author":"Liu","year":"2016","journal-title":"Cornea"},{"key":"R4-20261005","doi-asserted-by":"crossref","first-page":"6171","DOI":"10.3390\/jcm11206171","article-title":"Comparison of corneal higher-order aberrations following topography-guided LASIK and SMILE for myopic correction: A propensity score matching analysis","volume":"11","author":"Kang","year":"2022","journal-title":"J Clin Med"},{"key":"R5-20261005","doi-asserted-by":"crossref","first-page":"399","DOI":"10.3390\/jpm13030399","article-title":"Higher-order aberrations of topography-guided LASIK and wavefront-optimized LASIK in high- and low-myopic eyes: A non-randomized controlled trial","volume":"13","author":"Mai","year":"2023","journal-title":"J Pers Med"},{"key":"R6-20261005","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1097\/j.jcrs.0000000000000176","article-title":"Clinical outcomes after topography-guided LASIK: Comparing results based on a new topography analysis algorithm with those based on manifest refraction","volume":"46","author":"Lobanoff","year":"2020","journal-title":"J Cataract Refract Surg"},{"key":"R7-20261005","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1097\/j.jcrs.0000000000000910","article-title":"Clinical and refractive outcomes after topography-guided refractive surgery planned using Phorcides surgery planning software","volume":"48","author":"Stulting","year":"2022","journal-title":"J Cataract Refract Surg"},{"key":"R8-20261005","doi-asserted-by":"crossref","first-page":"2815","DOI":"10.2147\/OPTH.S429991","article-title":"Topography-guided LASIK: A prospective study evaluating patient-reported outcomes","volume":"17","author":"Rush","year":"2023","journal-title":"Clin Ophthalmol"},{"key":"R9-20261005","doi-asserted-by":"crossref","first-page":"3012","DOI":"10.4103\/ijo.IJO_218_20","article-title":"Pupillodynamics and corneal spherical aberrations in a set of Indian cataract patients and its implications for aberrometric customisation of intraocular lenses","volume":"68","author":"Paryani","year":"2020","journal-title":"Indian J Ophthalmol"},{"key":"R10-20261005","doi-asserted-by":"crossref","first-page":"3776","DOI":"10.3390\/jcm10173776","article-title":"Comparison of 6.0 mm versus 6.5 mm optical zone on visual outcomes after LASIK","volume":"10","author":"Moshirfar","year":"2021","journal-title":"J Clin Med"},{"key":"R11-20261005","doi-asserted-by":"crossref","first-page":"870330","DOI":"10.3389\/fmed.2022.870330","article-title":"Comparison of corneal optical quality after SMILE, wavefront-optimized LASIK and topography-guided LASIK for myopia and myopic astigmatism","volume":"9","author":"Zhang","year":"2022","journal-title":"Front Med (Lausanne)"},{"key":"R12-20261005","doi-asserted-by":"crossref","first-page":"e0279357","DOI":"10.1371\/journal.pone.0279357","article-title":"Comparison of refractive and visual acuity results after Contoura\u00ae vision topography-guided LASIK planned with the phorcides analytic engine to results after wavefront-optimized LASIK in eyes with oblique astigmatism","volume":"17","author":"Brunson","year":"2022","journal-title":"PLoS One"},{"key":"R13-20261005","doi-asserted-by":"crossref","first-page":"3227","DOI":"10.2147\/OPTH.S272085","article-title":"Predictions of residual astigmatism from surgical planning for topographic-guided LASIK based on anterior corneal astigmatism (LYRA protocol) vs the phorcides analytic engine","volume":"14","author":"Motwani","year":"2020","journal-title":"Clin Ophthalmol"},{"key":"R14-20261005","doi-asserted-by":"crossref","first-page":"449","DOI":"10.3928\/1081597X-20200609-01","article-title":"Effect of the vectorial difference between manifest refractive astigmatism and anterior corneal astigmatism on topography-guided LASIK outcomes","volume":"36","author":"Wallerstein","year":"2020","journal-title":"J Refract Surg"},{"key":"R15-20261005","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1186\/s12886-018-0920-1","article-title":"AstigMATIC: An automatic tool for standard astigmatism vector analysis","volume":"18","author":"Gauvin","year":"2018","journal-title":"BMC Ophthalmol"}],"container-title":["Indian Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/IJO.IJO_3110_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T14:01:15Z","timestamp":1791208875000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/IJO.IJO_3110_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,24]]},"references-count":15,"journal-issue":{"issue":"Suppl 3","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/ijo.ijo_3110_25","relation":{},"ISSN":["0301-4738","1998-3689"],"issn-type":[{"value":"0301-4738","type":"print"},{"value":"1998-3689","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,24]]},"assertion":[{"value":"2025-12-04","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-24","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}