{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:30:17Z","timestamp":1786649417133,"version":"build-2736575974"},"reference-count":22,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"9","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>This study aimed to compare the safety, efficacy, and visual outcomes of 80-microns LASIK versus 100-microns LASIK in managing myopia and myopic astigmatism. The study was conducted at a tertiary care hospital in North India.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This was a prospective contralateral eye study that included patients with myopia and myopic astigmatism seeking refractive correction. The eligibility criteria included normal corneal topography, an epithelial thickness less than 60 microns, a calculated percentage tissue ablation (with 100-microns flap) less than 40%, a calculated residual stromal bed thickness (with 100-microns flap) more than 300 microns, and willingness to participate and follow up. Patients with glaucoma, cataracts, other visually disabling ocular pathologies, and a history of past ocular surgery were excluded. All patients underwent LASIK with 80-microns LASIK in one eye and 100-microns LASIK in the other eye. The patients were followed up for 6 months, and the results were analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The study included 216 eyes of 108 patients. The mean preoperative spherical equivalent in the 80-microns group and the 100-microns group was -3.53 \u00b1 1.81 and -3.69 \u00b1 1.32 diopters, respectively (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.78). The mean 6 months decimal postoperative UCVA was 0.98 \u00b1 0.13 in the 80-microns group and 0.97 \u00b1 0.14 in the 100-microns group (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.99). The postoperative change in the higher-order aberration profile was comparable in both groups (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.78). The percentage tissue ablation was significantly lower in the 80-microns group (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.002). The incidence of flap micro striae and OBL was higher in the 80-microns group, while neither of these had any visual implications.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The study concluded that 80-microns LASIK is an efficacious and safe alternative to 100-micron LASIK, especially useful in patients with higher myopia.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_3213_23","type":"journal-article","created":{"date-parts":[[2024,8,23]],"date-time":"2024-08-23T21:24:25Z","timestamp":1724448265000},"page":"1308-1314","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Comparison between 80-microns versus 100-microns flap femtosecond LASIK for correction of myopia and myopic astigmatism"],"prefix":"10.4103","volume":"72","author":[{"given":"Sudarshan","family":"Khokhar","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deeksha","family":"Rani","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hemant","family":"Jhajharia","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saumya","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aishwarya","family":"Rathod","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarika","family":"Rajput","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,8,23]]},"reference":[{"key":"R1-20260427","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1111\/j.1444-0938.2012.00761.x","article-title":"Corneal refractive surgery: Past to present","volume":"95","author":"McAlinden","year":"2012","journal-title":"Clin Exp Optom"},{"key":"R2-20260427","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1002\/lsm.1900100511","article-title":"Laser in situ keratomileusis","volume":"10","author":"Pallikaris","year":"1990","journal-title":"Lasers Surg Med"},{"key":"R3-20260427","first-page":"312","article-title":"Iatrogenic keratectasia after laser in situ keratomileusis","volume":"14","author":"Seiler","year":"1998","journal-title":"J Refract Surg Thorofare NJ 1995"},{"key":"R4-20260427","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1080\/08820538.2019.1569075","article-title":"Post-LASIK ectasia: Twenty years of a conundrum","volume":"34","author":"Ambr\u00f3sio","year":"2019","journal-title":"Semin Ophthalmol"},{"key":"R5-20260427","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1097\/01.icu.0000233963.26628.f0","article-title":"Post-laser in-situ keratomileusis ectasia: Current understanding and future directions","volume":"17","author":"Randleman","year":"2006","journal-title":"Curr Opin Ophthalmol"},{"key":"R6-20260427","doi-asserted-by":"crossref","first-page":"1921","DOI":"10.1016\/j.jcrs.2004.09.055","article-title":"Simultaneous laser in situ keratomileusis on the stromal bed and undersurface of the flap in eyes with high myopia and thin corneas","volume":"31","author":"Joo","year":"2005","journal-title":"J Cataract Refract Surg"},{"key":"R7-20260427","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1097\/ICU.0b013e328302cc77","article-title":"Thin-flap laser-assisted in situ keratomileusis","volume":"19","author":"Slade","year":"2008","journal-title":"Curr Opin Ophthalmol"},{"key":"R8-20260427","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1097\/j.jcrs.0000000000000484","article-title":"Eighty-micron flap femtosecond-assisted LASIK for the correction of myopia and myopic astigmatism","volume":"47","author":"Bages-Rousselon","year":"2021","journal-title":"J Cataract Refract Surg"},{"key":"R9-20260427","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1016\/j.jcrs.2009.12.025","article-title":"Influence of flap thickness on visual and refractive outcomes after laser in situ keratomileusis performed with a mechanical keratome","volume":"36","author":"Bansal","year":"2010","journal-title":"J Cataract Refract Surg"},{"key":"R10-20260427","first-page":"S77","article-title":"Wavefront-guided excimer laser ablation using photorefractive keratectomy and sub-Bowman\u2019s keratomileusis: A contralateral eye study","volume":"24","author":"Durrie","year":"2008","journal-title":"J Refract Surg Thorofare NJ 1995"},{"key":"R11-20260427","first-page":"1290","article-title":"The effect of flap thickness on the visual and refractive outcome of myopic laser in situ keratomileusis","volume":"19","author":"Eleftheriadis","year":"2005","journal-title":"Eye Lond Engl"},{"key":"R12-20260427","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1016\/j.jcrs.2004.12.058","article-title":"Thin flap laser in situ keratomileusis: Analysis of contrast sensitivity, visual, and refractive outcomes","volume":"31","author":"Cobo-Soriano","year":"2005","journal-title":"J Cataract Refract Surg"},{"key":"R13-20260427","first-page":"222","article-title":"Persistent subepithelial haze in thin-flap LASIK","volume":"26","author":"Hafezi","year":"2010","journal-title":"J Refract Surg Thorofare NJ 1995"},{"key":"R14-20260427","doi-asserted-by":"crossref","first-page":"584","DOI":"10.3928\/1081597X-20170621-06","article-title":"A Technique to reduce incidence of opaque bubble layer formation during LASIK flap creation using the VisuMax femtosecond laser","volume":"33","author":"Wu","year":"2017","journal-title":"J Refract Surg"},{"key":"R15-20260427","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1097\/ICU.0000000000000070","article-title":"Microkeratome versus femtosecond flaps: Accuracy and complications","volume":"25","author":"Santhiago","year":"2014","journal-title":"Curr Opin Ophthalmol"},{"key":"R16-20260427","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1097\/ICU.0000000000000276","article-title":"Percent tissue altered and corneal ectasia","volume":"27","author":"Santhiago","year":"2016","journal-title":"Curr Opin Ophthalmol"},{"key":"R17-20260427","doi-asserted-by":"crossref","first-page":"2995","DOI":"10.4103\/ijo.IJO_450_20","article-title":"Validity of percentage tissue altered as a screening formula for post laser-assisted in-situ keratomileusis ectasia in Indian eyes","volume":"68","author":"Bhatia","year":"2020","journal-title":"Indian J Ophthalmol"},{"key":"R18-20260427","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/j.jcrs.2013.08.055","article-title":"Opaque bubble layer: Incidence, risk factors, and clinical relevance","volume":"40","author":"Liu","year":"2014","journal-title":"J Cataract Refract Surg"},{"key":"R19-20260427","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/j.jcrs.2007.10.026","article-title":"Incidence, possible risk factors, and potential effects of an opaque bubble layer created by a femtosecond laser","volume":"34","author":"Kaiserman","year":"2008","journal-title":"J Cataract Refract Surg"},{"key":"R20-20260427","doi-asserted-by":"crossref","first-page":"2325","DOI":"10.2147\/OPTH.S121237","article-title":"Flap double twist technique for prevention of LASIK flap striae","volume":"10","author":"Nabil","year":"2016","journal-title":"Clin Ophthalmol"},{"key":"R21-20260427","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1016\/j.jcrs.2004.10.056","article-title":"Thin flap laser in situ keratomileusis: Flap dimensions with the Moria LSK-One manual microkeratome using the 100-\u03bcm head","volume":"31","author":"Duffey","year":"2005","journal-title":"J Cataract Refract Surg"},{"key":"R22-20260427","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.1038\/eye.2017.107","article-title":"Corneal densitometry after photorefractive keratectomy, laser-assisted in situ keratomileusis, and small-incision lenticule extraction","volume":"31","author":"Poyales","year":"2017","journal-title":"Eye"}],"container-title":["Indian Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/IJO.IJO_3213_23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T18:53:54Z","timestamp":1786647234000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/IJO.IJO_3213_23"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,23]]},"references-count":22,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/ijo.ijo_3213_23","relation":{},"ISSN":["0301-4738","1998-3689"],"issn-type":[{"value":"0301-4738","type":"print"},{"value":"1998-3689","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8,23]]},"assertion":[{"value":"2023-12-08","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-05-14","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}