{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T09:42:44Z","timestamp":1790847764229,"version":"4.1.0"},"reference-count":32,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","license":[{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To determine the association between serum lipid levels and primary open-angle glaucoma (POAG).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>In this case-control study, 50 patients with POAG documented by clinical tests using standard ophthalmologic equipment and 50 age-matched controls were investigated. Twelve-hour fasting serum lipid profiles, including total cholesterol, serum triglycerides, low-density lipoproteins (LDLs), and high-density lipoproteins (HDLs), were compared between the cases and controls.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The mean age of cases and controls was 62.84 \u00b1 9.68 and 60.12 \u00b1 8.65, respectively (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.65). High total cholesterol levels (&gt;200 mg\/dl) were found in 23 cases (46%) and 8 controls (16%); high serum triglyceride levels (&gt;150 mg\/dl) were found in 24 cases (48%) and 7 controls (14%); high LDL levels (130 mg\/dl) were found in 28 cases (56%) and 9 controls (18%); and low HDL levels (&lt;40 mg\/dl) were found in 38 cases (76%) and 30 controls (60%). The mean total cholesterol levels were 205.24 \u00b1 36.90 mg\/dl in cases and 177.68 \u00b1 22.56 mg\/dl in controls (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001); the mean serum triglyceride levels were 150.42 \u00b1 49.55 mg\/dl and 130.84 \u00b1 23.16 mg\/dl, respectively (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.013); and the mean LDL levels were 139.50 \u00b1 31.03 mg\/dl and 114.96 \u00b1 17.73 mg\/dl, respectively (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001). The mean cholesterol, triglyceride, and LDL levels were significantly higher in cases than in controls (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The present study shows that higher proportion of POAG patients have dyslipidemia compared to age-matched controls. Though these findings need to be replicated by others. This study opens new vistas for further studies, such as lowering dyslipidemia, lowering the intra-ocular pressure and incidence of POAG, and whether the use of statins to reduce dyslipidemia affects the progression of POAG.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_3233_22","type":"journal-article","created":{"date-parts":[[2023,5,17]],"date-time":"2023-05-17T03:45:35Z","timestamp":1684295135000},"page":"1948-1952","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":10,"title":["Study of the relationship between serum lipid levels and primary open-angle glaucoma"],"prefix":"10.4103","volume":"71","author":[{"given":"Rajesh Subhash","family":"Joshi","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Government Medical College, Nagpur, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vaishnavi 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