{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T17:27:18Z","timestamp":1786728438867,"version":"build-2736575974"},"reference-count":30,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"11","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,11]]},"abstract":"\n Purpose:<\/jats:title>\n To compare the surgical outcomes of twin-site phacotrabeculectomy with Mitomycin C (MMC) in primary open-angle glaucoma (POAG) versus primary angle-closure glaucoma (PACG).<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n Prospective, comparative, observational study. Patients with visually significant cataract and primary glaucoma were divided into two groups: POAG and PACG. They underwent twin-site phacotrabeculectomy with MMC and followed up on days 1, 15, 1 month, 6 months, and 12 months. Baseline and follow-up visits were compared to find the differences in intraocular pressure (IOP), antiglaucoma medications (AGM), success rates, anterior chamber depth (ACD), and axial length (AXL).<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n There were 50 eyes each in POAG and PACG groups. Mean IOP reduction from baseline to 12 months (21.22 \u00b1 6.0 to 11.40 \u00b1 2.8\u2014POAG group vs 24.16 \u00b1 7.6 to 12.42 \u00b1 3.2\u2014PACG group) was statistically significant in both groups (\n P<\/jats:italic>\n < 0.001), but no significant difference between groups (\n P<\/jats:italic>\n = 0.095). There was a statistically significant decline in the number of AGM in POAG [1.66 (0.7) to 0.38 (0.7),\n P<\/jats:italic>\n < 0.001] and PACG [2.10 (0.7) to 0.70 (0.8),\n P<\/jats:italic>\n < 0.001]; the decline was more in POAG (\n P<\/jats:italic>\n = 0.012) at last visit. Probability of overall (complete and qualified) success at 12 months postop was 72.0% [95% confidence interval (CI): 57.4\u201382.4] in PACG and 84.0% (95% CI: 70.5\u201391.7) in POAG group. There was a significant increase in ACD and a decrease in AXL in both groups (\n P<\/jats:italic>\n < 0.001). More interventions were required in the PACG group (38,\n P<\/jats:italic>\n = 0.012).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Phacotrabeculectomy with MMC causes a significant reduction in IOP and improvement in biometric parameters in both POAG and PACG. Patients with PACG required more postoperative interventions, while a lesser number of antiglaucoma medications were needed in POAG patients.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/ijo.ijo_324_23","type":"journal-article","created":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T11:17:56Z","timestamp":1697800676000},"page":"3528-3533","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Comparative study of surgical outcomes of twin-site phacotrabeculectomy with mitomycin C in primary open-angle glaucoma versus primary angle-closure glaucoma"],"prefix":"10.4103","volume":"71","author":[{"given":"Devendra","family":"Maheshwari","sequence":"first","affiliation":[{"name":"Department of Glaucoma, Aravind Eye Hospital, Tirunelveli, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madhavi Ramanatha","family":"Pillai","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, Aravind Eye Hospital, Tirunelveli, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Swathi","family":"Kanduri","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, Aravind Eye Hospital, Tirunelveli, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Indu J","family":"Nair","sequence":"additional","affiliation":[{"name":"Department of Retina, Chaithanya Eye Hospital and Research Institute, Trivandrum, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohideen Abdul","family":"Kader","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, Aravind Eye Hospital, Tirunelveli, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rengappa","family":"Ramakrishnan","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, Aravind Eye Hospital, Tirunelveli, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,10,20]]},"reference":[{"key":"R1-20260511","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1136\/bjo.2005.081224","article-title":"The number of people with glaucoma worldwide in 2010 and 2020","volume":"90","author":"Quigley","year":"2006","journal-title":"Br J Ophthalmol"},{"key":"R2-20260511","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1016\/j.survophthal.2013.09.003","article-title":"Population-based glaucoma prevalence studies in Asians","volume":"59","author":"Cho","year":"2014","journal-title":"Surv Ophthalmol"},{"key":"R3-20260511","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1016\/S0161-6420(92)31934-7","article-title":"Prevalence of age-related lens opacities in a population. 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