{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T17:26:43Z","timestamp":1786728403729,"version":"build-2736575974"},"reference-count":23,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"10","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To evaluate retinal and choroidal alterations in eyes with inactive ocular sarcoidosis and to compare the findings with healthy controls.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This cross-sectional study included 11 patients with inactive ocular sarcoidosis (study group) and 11 healthy individuals (control group). Retinal and choroidal vascular differences were evaluated using optical coherence tomography angiography (OCTA) and enhanced depth imaging\u2013optical coherence tomography (EDI-OCT).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      A total of 21 eyes of ocular sarcoidosis patients without active inflammation and 22 eyes of healthy controls were analyzed. The mean whole-image deep capillary plexus vessel density was significantly lower in the study group than in the control group (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.03). The acircularity index values were significantly higher, and the foveal density-300 values were significantly lower in the study group than in the control group (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.01, both). The flow areas of the choriocapillaris at 1-, 2-, and 3-mm radius areas were also significantly lower in the study group (all\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.01). The mean choroidal thickness (CT) was significantly lower in all regions between nasal and temporal at 3000 \u03bcm in the study group (all\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05). The choroidal vascularity index (CVI) values were also significantly lower in the study group (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.01).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Ocular sarcoidosis was associated with a reduction in CT and the CVI with a decrease in retinal vessel density and choriocapillary flow parameters. The combination of OCTA and EDI-OCT imaging may be useful in monitoring ocular sarcoidosis eyes to detect alterations in the retinal and choroidal layers.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_3262_22","type":"journal-article","created":{"date-parts":[[2023,9,21]],"date-time":"2023-09-21T12:14:28Z","timestamp":1695298468000},"page":"3367-3374","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Quantitative evaluation of retinal and choroidal microcirculation in inactive ocular sarcoidosis"],"prefix":"10.4103","volume":"71","author":[{"given":"Kubra Ozdemir","family":"Yalcinsoy","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, University of Health Sciences, Ulucanlar Eye Education and Research Hospital, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasemin Ozdamar","family":"Erol","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University of Health Sciences, Ulucanlar Eye Education and Research Hospital, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gozde","family":"Hondur","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University of Health Sciences, Ulucanlar Eye Education and Research Hospital, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pinar Cakar","family":"Ozdal","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University of Health Sciences, Ulucanlar Eye Education and Research Hospital, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,9,29]]},"reference":[{"key":"R1-20251009","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1080\/25785826.2021.1940740","article-title":"Characteristics and management of ocular sarcoidosis","volume":"45","author":"Takase","year":"2022","journal-title":"Immunol Med"},{"key":"R2-20251009","first-page":"160","article-title":"Members of Scientific Committee of First International Workshop on Ocular Sarcoidosis","volume":"17","author":"Herbort","year":"2009","journal-title":"International criteria for the diagnosis of ocular sarcoidosis: Results of the first International Workshop On Ocular Sarcoidosis (IWOS). 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