{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T16:42:10Z","timestamp":1786725730299,"version":"build-2736575974"},"reference-count":30,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To perform tear meniscus particle analysis using anterior segment spectral domain-optical coherence tomography (SD-OCT) and ImageJ software in keratoconus patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A total of 76 participants (76 eyes) were included in the study. A comprehensive analysis of tear meniscus parameters, including tear meniscus height (TMH), tear meniscus depth (TMD), tear meniscus turbidity (TMT), and percentage of area occupied by particles (PAOP) within the meniscus, was performed in kerataconus patients and healthy controls.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      TMT was significantly higher in the keratoconus group, while PAOP was significantly lower (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05). However, TMH and TMD did not show significant differences between the two groups (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &gt; 0.05). There was a negative correlation observed between TMT and PAOP. In binary logistic regression analysis, TMT and Schirmer score were found to be the most influential factors in predicting keratoconus (odds ratio [OR] = 0.995,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.039 and OR = 1.143,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.021, respectively).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>This study revealed novel findings on analysis of the tear film in keratoconus patients, with higher TMT and lower POAP levels in the keratoconus group compared to the healthy control group.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_3298_23","type":"journal-article","created":{"date-parts":[[2024,7,29]],"date-time":"2024-07-29T08:09:41Z","timestamp":1722240581000},"page":"1136-1141","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Tear meniscus particle analysis with anterior segment optical coherence tomography in keratoconus"],"prefix":"10.4103","volume":"72","author":[{"given":"Sevim Ayca","family":"Seyyar","sequence":"first","affiliation":[{"name":"Ophthalmology Department, Gaziantep University Hospital, Gaziantep, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u015eaban","family":"B\u00fcy\u00fckbayram","sequence":"additional","affiliation":[{"name":"Ophthalmology Department, Gaziantep University Hospital, Gaziantep, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gizem G\u00fcrbostan","family":"Soysal","sequence":"additional","affiliation":[{"name":"Ophthalmology Clinic, Ersin Arslan Education and Research Hospital, Gaziantep, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serhat","family":"Ayla","sequence":"additional","affiliation":[{"name":"Ophthalmology Department, Gaziantep University Hospital, Gaziantep, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Levent","family":"Do\u011fan","sequence":"additional","affiliation":[{"name":"Ophthalmology Clinic, Kilis State Hospital, Kilis, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ecem \u00d6nder","family":"Toku\u00e7","sequence":"additional","affiliation":[{"name":"Ophthalmology Department, Kocaeli University Hospital, Kocaeli, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murat","family":"Mercanl\u0131","sequence":"additional","affiliation":[{"name":"Ophthalmology Clinic, D\u00fcnyag\u00f6z Hospital, Adana, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alper","family":"Mete","sequence":"additional","affiliation":[{"name":"Ophthalmology Department, Gaziantep University Hospital, Gaziantep, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,7,29]]},"reference":[{"key":"R1-20260507","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1097\/00003226-199603000-00006","article-title":"Biomicroscopic signs and disease severity in keratoconus. 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