{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T05:40:17Z","timestamp":1793252417672,"version":"4.5.0"},"reference-count":29,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To study the epidemiological pattern and diagnostic accuracy of histopathologically proven eyelid lesions over a period of two decades.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A retrospective study of all histopathologically proven eyelid lesions from April 1996 to March 2016 was conducted. The lesions were broadly categorized as benign or malignant. Inflammatory and infectious lesions were included under the benign category. The percentage and diagnostic accuracy of each lesion was calculated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      There were a total of 994 (M = 551, F = 443) cases. The mean age of the patients was 43.5 \u00b1 19.9 years. There were 809 (81.4%) benign and 185 (18.6%) malignant lesions. Benign lesions were commonly seen in the fourth decade, while the malignant ones in the late fifth decade. The upper lid was the most common site in both groups (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 481, 48.4%). The commonest benign lesion was chalazion (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 484, 59.8%). Dermal nevus (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 94, 11.6%) was the most common benign neoplasm, while Molluscum contagiosum (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 25, 3.09%) was the most common infectious lesion. Sebaceous gland carcinoma (SGC) (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 103, 55.7%) was the leading malignant lesion followed by basal cell carcinoma (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 39, 21.1%). Eleven malignant cases were misdiagnosed as benign (5.9%). Chalazion (99.1%) and SGC (65%) had the highest diagnostic accuracy, while Molluscum (40%) and squamous cell carcinoma (40%) were the most misdiagnosed lesions in the respective groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Benign eyelid lesions are far more common than malignant ones. Atypical and rare presentations may lead to misdiagnosis. Knowledge of epidemiological patterns and clinical features can help in achieving higher diagnostic accuracy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_428_21","type":"journal-article","created":{"date-parts":[[2021,12,27]],"date-time":"2021-12-27T06:00:43Z","timestamp":1640584843000},"page":"43-50","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":27,"title":["The spectrum and clinicopathological correlation of eyelid lesions: Twenty years\u2019 experience at a tertiary eye care center in South India"],"prefix":"10.4103","volume":"70","author":[{"given":"Prabrisha","family":"Banerjee","sequence":"first","affiliation":[{"name":"Orbit, Oculoplasty, Reconstructive and Aesthetic Services, Sankara Nethralaya, Medical Research Foundation, Chennai, Tamil Nadu, 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