{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:30:17Z","timestamp":1786649417141,"version":"build-2736575974"},"reference-count":6,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"10","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>This study aims to present a case series detailing sight-threatening ocular and adnexal manifestations following dengue fever.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A retrospective observational study was conducted, analyzing records of patients presenting with ocular manifestations post dengue fever at a tertiary eye care institute in Uttar Pradesh from October 2023 to November 2023. Demographic details, systemic comorbidities, and detailed ophthalmic examinations were recorded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Fifteen eyes of 13 patients with dengue fever were studied. The mean age of presentation was 39.07 years, with a male predominance (84.61%). Systemic comorbidities were noted in 30.76% (diabetes mellitus) and 23.07% (hypertension) of patients. Thrombocytopenia was observed in 53.84% of patients, while 23.07% required blood transfusions, and 15.38% experienced systemic bleeding episodes. The majority of cases were unilateral (84.61%), with the best-corrected visual acuity of perception of light in 84.61% of cases. Diminution of vision was the most common presenting symptom (84.61%), followed by pain (53.84%), redness (38.46%), and watering (23.07%). Major ocular manifestations included panophthalmitis (26.07%), total ophthalmoplegia (26.07%), endogenous endophthalmitis (20%), central retinal artery occlusion (20%), retinal hemorrhage (20%), ischemic optic neuropathy (20%), orbital cellulitis (13.3%), proptosis (13.3%), retrobulbar hemorrhage (13.3%), retinal detachment (13.3%), and foveolitis (6.7%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The diverse array of ocular and adnexal manifestations in dengue hemorrhagic fever may result in permanent visual loss, emphasizing the need for adequate treatment and timely intervention. The risk of sight-threatening complications underscores the importance of early screening by ophthalmologists and increased public awareness.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_430_24","type":"journal-article","created":{"date-parts":[[2024,9,27]],"date-time":"2024-09-27T11:01:00Z","timestamp":1727434860000},"page":"1495-1500","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":4,"title":["Ocular and adnexal manifestations post dengue hemorrhagic fever"],"prefix":"10.4103","volume":"72","author":[{"given":"Veenu","family":"Maan","sequence":"first","affiliation":[{"name":"Department of Pediatric Ophthalmology, Strabismus and Neuro-Ophthalmology, CL Gupta Eye Institute, Ram Ganga Vihar, Phase II (Ext), Moradabad, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Subhamita","family":"Guha","sequence":"additional","affiliation":[{"name":"Department of Vitreoretina, CL Gupta Eye Institute, Ram Ganga Vihar, Phase II (Ext), Moradabad, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Himanshu","family":"Sapra","sequence":"additional","affiliation":[{"name":"Department of Optometry and Visual Sciences, CL Gupta Eye Institute, Ram Ganga Vihar, Phase II (Ext), Moradabad, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lokesh","family":"Chauhan","sequence":"additional","affiliation":[{"name":"Department of Clinical and Public Health Research, CL Gupta Eye Institute, Ram Ganga Vihar, Phase II (Ext), Moradabad, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,9,27]]},"reference":[{"key":"R2-20260427","first-page":"373","article-title":"Dengue in India","volume":"136","author":"Gupta","year":"2012","journal-title":"Indian J Med Res"},{"key":"R3-20260427","doi-asserted-by":"crossref","first-page":"617","DOI":"10.4103\/ijo.IJO_1588_20","article-title":"Severe ocular and adnexal complications in dengue hemorrhagic fever: A report of 29 eyes","volume":"69","author":"Vijitha","year":"2021","journal-title":"Indian J Ophthalmol"},{"key":"R4-20260427","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1186\/s12879-023-08432-4","article-title":"Ophthalmic complications during the dengue epidemic in Reunion Island in 2020: A case series and review of the literature","volume":"23","author":"Mbu-Nyamsi","year":"2023","journal-title":"BMC Infect Dis"},{"key":"R5-20260427","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1007\/s40123-012-0002-z","article-title":"Ophthalmic complications of dengue Fever: A systematic review","volume":"1","author":"Yip","year":"2012","journal-title":"Ophthalmol Ther"},{"key":"R6-20260427","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1097\/ICU.0000000000000613","article-title":"Ocular manifestations of dengue","volume":"30","author":"Somkijrungroj","year":"2019","journal-title":"Curr Opin Ophthalmol"},{"key":"R7-20260427","doi-asserted-by":"crossref","first-page":"285","DOI":"10.3201\/eid1202.050274","article-title":"Eye Institute dengue-related ophthalmic complications workgroup. Ophthalmic complications of dengue","volume":"12","author":"Chan","year":"2006","journal-title":"Emerg Infect Dis"}],"container-title":["Indian Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/IJO.IJO_430_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T18:53:56Z","timestamp":1786647236000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/IJO.IJO_430_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,27]]},"references-count":6,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/ijo.ijo_430_24","relation":{},"ISSN":["0301-4738","1998-3689"],"issn-type":[{"value":"0301-4738","type":"print"},{"value":"1998-3689","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,27]]},"assertion":[{"value":"2024-02-16","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-05-20","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}