{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T14:52:43Z","timestamp":1791211963127,"version":"4.1.0"},"reference-count":38,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 3","license":[{"start":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T00:00:00Z","timestamp":1773273600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To analyze the independent risk factors associated with early emulsification in rhegmatogenous retinal detachments (RRDs) and determine the association between suboptimal fill of silicone oil (SO) and the onset of early emulsification.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>Retrospective observational cohort study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Single-center (institutional) study. Electronic medical records of 81 eyes (81 patients) with RRD undergoing pars-plana vitrectomy with SO injection (from July 2020 to June 2021) were evaluated. Eyes with &lt;6 weeks follow-up, combined RDs, eyes with active inflammation (&lt;3 months from surgery), keratoprothesis, and nystagmus were excluded. The demographic data, cause of RRD, degree of myopia, best corrected visual acuity, number of breaks, presence of inferior break, preoperative proliferative vitreoretinopathy, relaxing retinectomies, buckle encirclage, technique of oil injection, viscosity of SO, duration of tamponade, presence of suboptimal fill on ultra-widefield imaging, postoperative lens status, and intraocular pressure on follow-up were analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Outcome Measures:<\/jats:title>\n                    <jats:p>Univariate and multivariate logistic-regression analysis was performed to determine the independent risk factors associated with SO emulsification.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The mean age of the patients was 39.4 \u00b1 18.7 years. The mean duration of oil tamponade was 8.6 \u00b1 7.3 months. 58.0% eyes had suboptimal SO fill. On multivariate analysis, age of the patient (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.032), use of encirclage (0.006), and duration of oil-in-situ (0.015) were noted to have a significant association to SO emulsification. On analysis of eyes with oil duration &lt;6 months (n = 37), suboptimal fill was a significant associate to emulsification (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.025).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Suboptimal fill of SO in RRDs has a higher risk of early emulsification.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_565_25","type":"journal-article","created":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T16:02:05Z","timestamp":1773331325000},"page":"S464-S470","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Risk factors for early emulsification of silicone oil after surgery for rhegmatogenous retinal detachment"],"prefix":"10.4103","volume":"74","author":[{"given":"Ayushi","family":"Mohapatra","sequence":"first","affiliation":[{"name":"Shri Bhagwan Mahavir Vitreoretinal Services, Sankara Nethralaya, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I N","family":"Shilpa","sequence":"additional","affiliation":[{"name":"Shri Bhagwan Mahavir Vitreoretinal Services, Sankara Nethralaya, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aditi A K","family":"Agarwal","sequence":"additional","affiliation":[{"name":"Shri Bhagwan Mahavir Vitreoretinal Services, Sankara Nethralaya, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingam","family":"Gopal","sequence":"additional","affiliation":[{"name":"Shri Bhagwan Mahavir Vitreoretinal Services, Sankara Nethralaya, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muna","family":"Bhende","sequence":"additional","affiliation":[{"name":"Shri Bhagwan Mahavir Vitreoretinal Services, Sankara Nethralaya, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,3,12]]},"reference":[{"key":"R1-20261005","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1001\/archopht.1962.00960030594005","article-title":"The use of liquid silicone in retinal detachment surgery","volume":"68","author":"Cibis","year":"1962","journal-title":"Arch Ophthalmol"},{"key":"R2-20261005","doi-asserted-by":"crossref","first-page":"3172138","DOI":"10.1155\/2017\/3172138","article-title":"Vitreous substitutes: Old and new materials in vitreoretinal surgery","volume":"2017","author":"Alovisi","year":"2017","journal-title":"J Ophthalmol"},{"key":"R3-20261005","first-page":"83","article-title":"Final anatomic and visual outcomes 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surgery: A systemic review and meta-analysis","volume":"100","author":"Valent\u00edn-Bravo","year":"2022","journal-title":"Acta Ophthalmol"},{"key":"R7-20261005","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1080\/02713683.2024.2409883","article-title":"Complications of silicone oil as vitreous tamponade in pars plana vitrectomy: A Mini review","volume":"50","author":"Oliveira","year":"2025","journal-title":"Curr Eye Res"},{"key":"R8-20261005","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1111\/aos.14604","article-title":"Silicone oil in vitreoretinal surgery: Indications, complications, new developments and alternative long-term tamponade agents","volume":"99","author":"Chen","year":"2021","journal-title":"Acta Ophthalmol"},{"key":"R9-20261005","doi-asserted-by":"crossref","first-page":"1671","DOI":"10.1007\/s00417-014-2866-1","article-title":"Quantifying silicone oil emulsification in patients: Are we only seeing the tip of the iceberg?","volume":"253","author":"Chan","year":"2015","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"R10-20261005","doi-asserted-by":"crossref","first-page":"1810","DOI":"10.1038\/s41433-024-03027-y","article-title":"Refinements in the use of silicone oil as an intraocular tamponade","volume":"38","author":"Wilson","year":"2024","journal-title":"Eye (Lond)"},{"key":"R11-20261005","doi-asserted-by":"crossref","first-page":"e385","DOI":"10.1111\/aos.13258","article-title":"Towards better characterization and quantification of emulsification of silicone oil in vitro","volume":"95","author":"Chan","year":"2017","journal-title":"Acta Ophthalmol"},{"key":"R12-20261005","doi-asserted-by":"crossref","first-page":"794786","DOI":"10.3389\/fmed.2021.794786","article-title":"Characteristics of silicone oil emulsification after vitrectomy for rhegmatogenous retinal detachment: An ultrasound biomicroscopy study","volume":"8","author":"Zhao","year":"2022","journal-title":"Front Med 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