{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:25:29Z","timestamp":1787840729725,"version":"build-2784847793"},"reference-count":34,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","license":[{"start":{"date-parts":[[2024,12,27]],"date-time":"2024-12-27T00:00:00Z","timestamp":1735257600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To study the clinical profile of patients with microspherophakia and the factors associated with poor vision following lensectomy surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A multicenter, retrospective, cross-sectional analysis was conducted from January 2010 to June 2022 on patients diagnosed with microspherophakia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      A total of 102 eyes from 51 patients were enrolled, of whom 24 (47.1%) were male and 27 (52.9%) were female. All patients presented with bilateral involvement. The most common presenting complaint was defective vision, affecting 98 (96.1%) eyes. Patients exhibited varying degrees of lenticular myopia, with a mean refractive error of \u221213.54 \u00b1 11.92 D. Glaucoma was present in 36 (35.3%) eyes at presentation. Subluxation of the crystalline lens was observed in 50 (49.1%) eyes, dislocation of the lens into the anterior chamber in 24 (23.5%) eyes, and dislocation into the vitreous cavity in 4 (3.9%) eyes. Limbal or pars plana lensectomy was performed in 54 (52.9%) eyes. The mean corrected visual acuity improved from 1.05 \u00b1 0.82 logMAR units to 0.82 \u00b1 0.79 logMAR units after lensectomy (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.029). Poor postoperative visual acuity (less than 20\/200) was associated with poor preoperative visual acuity (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.005), presence of glaucoma at the first visit (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.013), and intraocular pressure &gt;30 mmHg (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Microspherophakia is associated with high lenticular myopia, subluxation, and dislocation of the crystalline lens. Significant improvement in postoperative vision was observed after lensectomy. Factors associated with poor postoperative vision included poor preoperative corrected vision, presence of glaucoma, and high intraocular pressure.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_607_24","type":"journal-article","created":{"date-parts":[[2024,12,27]],"date-time":"2024-12-27T10:00:25Z","timestamp":1735293625000},"page":"335-340","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Clinical spectrum of bilateral microspherophakia and risk factors associated with poor visual outcomes following lensectomy surgery - A multicentric study"],"prefix":"10.4103","volume":"73","author":[{"given":"Monalisa","family":"Mohapatra","sequence":"first","affiliation":[{"name":"Paediatric Ophthalmology Services, MGM Eye Institute, Raipur, Chhattisgarh, India"},{"name":"The Bodhya Eye Consortium, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shailja","family":"Tibrewal","sequence":"additional","affiliation":[{"name":"The Bodhya Eye Consortium, India"},{"name":"Department of Paediatric Ophthalmology, Strabismus and Neuro-ophthalmology CL Gupta Eye Institute and Department of Genetics, Dr. Shoff\u2019s Charity Eye Hospital, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samrat","family":"Chatterjee","sequence":"additional","affiliation":[{"name":"The Bodhya Eye Consortium, India"},{"name":"Cornea and Anterior Segment Services, MGM Eye Institute, Raipur, Chhattisgarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pradeep","family":"Agarwal","sequence":"additional","affiliation":[{"name":"The Bodhya Eye Consortium, India"},{"name":"Department of Paediatric Ophthalmology, Strabismus and Neuro-ophthalmology CL Gupta Eye Institute, Moradabad, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chintan","family":"Shah","sequence":"additional","affiliation":[{"name":"The Bodhya Eye Consortium, India"},{"name":"Department of Paediatric Ophthalmology and Strabismus, Sadguru Netra Chikitsalaya, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajat","family":"Kapoor","sequence":"additional","affiliation":[{"name":"The Bodhya Eye Consortium, India"},{"name":"Department of Paediatric Ophthalmology, Strabismus and Neuro-ophthalmoloy, Pushpagiri Vitreo Retina Institute, Secunderabad, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anupam","family":"Sahoo","sequence":"additional","affiliation":[{"name":"Paediatric Ophthalmology Services, MGM Eye Institute, Raipur, Chhattisgarh, India"},{"name":"The Bodhya Eye Consortium, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pradhanya","family":"Sen","sequence":"additional","affiliation":[{"name":"The Bodhya Eye Consortium, India"},{"name":"Department of Paediatric Ophthalmology and Strabismus, Sadguru Netra Chikitsalaya, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veenu","family":"Maan","sequence":"additional","affiliation":[{"name":"The Bodhya Eye Consortium, India"},{"name":"Department of Paediatric Ophthalmology, Strabismus and Neuro-ophthalmology CL Gupta Eye Institute, Moradabad, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonu Arjun","family":"Shetty","sequence":"additional","affiliation":[{"name":"Paediatric Ophthalmology Services, MGM Eye Institute, Raipur, Chhattisgarh, India"},{"name":"The Bodhya Eye Consortium, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samir","family":"Sutar","sequence":"additional","affiliation":[{"name":"The Bodhya Eye Consortium, India"},{"name":"Department of Paediatric Ophthalmology, Strabismus and Neuro-ophthalmology CL Gupta Eye Institute, Moradabad, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priya","family":"Goyal","sequence":"additional","affiliation":[{"name":"The Bodhya Eye Consortium, India"},{"name":"Department of Paediatric Ophthalmology, Strabismus and Neuro-ophthalmology CL Gupta Eye Institute and Department of Genetics, Dr. Shoff\u2019s Charity Eye Hospital, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suma","family":"Ganesh","sequence":"additional","affiliation":[{"name":"The Bodhya Eye Consortium, India"},{"name":"Department of Paediatric Ophthalmology, Strabismus and Neuro-ophthalmology CL Gupta Eye Institute and Department of Genetics, Dr. 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