{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:30:18Z","timestamp":1787758218680,"version":"build-2784847793"},"reference-count":22,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"10","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To study the effect of intraocular lens (IOL) implantation with and without ocular viscoelastic device (OVD) on posterior capsular opacification (PCO) in eyes with phacoemulsification.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This prospective, comparative, and randomized case series included 70 patients (140 eyes) with senile cataracts scheduled for phacoemulsification and IOL implantation in a tertiary eye c are center. One eye of each patient was randomized to one of the two groups, namely, control and OVD. After phacoemulsification, the IOL was placed in the capsular bag under balanced salt solution (BSS) in the control group, whereas the IOL was placed under OVD in the OVD group. PCO was analyzed by an independent observer at 6, 12, and 18 months under slit-lamp illumination.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The mean age of the participants in the two groups was 61.2 (\u00b19.9) years. Of the total participants, 68 (48.5%) were men and 72 (51.5%) were women. The mean keratometry (K1, K2) values of the OVD (44.26 \u00b1 1.43, 44.93 \u00b1 1.66) and control (44.51 \u00b1 1.74, 44.69 \u00b1 1.49) groups were similar. The mean IOL powers of the control and OVD groups were 21.25 (\u00b11.94) and 21.53 (\u00b11.86), respectively (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.463). The mean best-corrected visual acuity (BCVA) of the control group at 6-, 12-, and 18-month follow-ups were 0.622 (\u00b10.253), 0.315 (\u00b10.203), and 0.063 (\u00b10.163), respectively, whereas those of the OVD group were 0.592 (\u00b10.253), 0.336 (\u00b10.169), and 0.066 (\u00b10.118), respectively (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.922).\n                      <jats:italic toggle=\"yes\">None of the patients had postoperative raised intraocular pressure (IOP), uveitis, or endophthalmitis<\/jats:italic>\n                      . Three and four eyes in the control and OVD groups, respectively, required neodymium-doped yttrium aluminum garnet (ND: YAG) capsulotomy at study termination (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.999).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The hydroimplantation technique of the placement of hydrophilic IOL did not reduce the PCO rate in the 18-month follow-up period. The ND: YAG capsulotomy rate did not differ between the groups.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_678_22","type":"journal-article","created":{"date-parts":[[2022,10,6]],"date-time":"2022-10-06T11:10:13Z","timestamp":1665054613000},"page":"3529-3533","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of posterior capsular opacification and neodymium-doped yttrium aluminum garnet capsulotomy rates in patients with hydrophilic intraocular lens implantation with and without ocular viscoelastic device"],"prefix":"10.4103","volume":"70","author":[{"given":"Rajesh Subhash","family":"Joshi","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Government Medical College, Nagpur, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanmay","family":"Surwade","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Government Medical College, Nagpur, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashwini","family":"Rasal","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Government Medical College, Nagpur, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,9,30]]},"reference":[{"key":"B1-20240828","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1186\/s12886-019-1051-z","article-title":"Posterior capsular opacification comparison between morphology and objective visual function","volume":"19","author":"Lu","year":"2019","journal-title":"BMC Ophthalmol"},{"key":"B2-20240828","doi-asserted-by":"crossref","first-page":"1579","DOI":"10.1038\/s41433-018-0131-2","article-title":"Three-year incidence of Nd:YAG capsulotomy and posterior capsule opacification and its relationship to monofocal acrylic IOL biomaterial:A UK Real World Evidence study","volume":"32","author":"Ursell","year":"2018","journal-title":"Eye (Lond)"},{"key":"B3-20240828","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ophtha.2016.09.027","article-title":"Cataract in the adult eye preferred practice pattern (R)","volume":"124","author":"Olson","year":"2017","journal-title":"Ophthalmology"},{"key":"B4-20240828","doi-asserted-by":"crossref","first-page":"363","DOI":"10.3109\/02713683.2012.748079","article-title":"Sealed-capsule, irrigation with distilled deionized water to prevent posterior capsule opacification--prospective randomized clinical trial","volume":"38","author":"R\u0119kas","year":"2013","journal-title":"Curr Eye Res"},{"key":"B5-20240828","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.ophtha.2016.11.010","article-title":"Long-term posterior capsule opacification reduction with square-edge polymethylmethacrylate intraocular lens:Randomized controlled study","volume":"124","author":"Shekhar","year":"2017","journal-title":"Ophthalmology"},{"key":"B6-20240828","doi-asserted-by":"crossref","first-page":"4566436","DOI":"10.1155\/2021\/4566436","article-title":"Long-term clinically significant posterior capsular opacification development pattern in eyes implanted with an aspheric monofocal intraocular lens with a square optic edge","volume":"2021","author":"Placeres Dab\u00e1n","year":"2021","journal-title":"J Ophthalmol"},{"key":"B7-20240828","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1016\/j.msec.2017.03.029","article-title":"UV-assisted treatment on hydrophobic acrylic IOLs anterior surface with methacryloyloxyethyl phosphorylcholine:Reducing inflammation and maintaining low posterior capsular opacification properties","volume":"75","author":"Huang","year":"2017","journal-title":"Mater Sci Eng C Mater Biol Appl"},{"key":"B8-20240828","doi-asserted-by":"crossref","first-page":"1440","DOI":"10.4103\/ijo.IJO_454_17","article-title":"Long-term results of trypan blue dye irrigation in the capsular bag to prevent posterior capsule opacification:A randomized trial","volume":"65","author":"Joshi","year":"2017","journal-title":"Indian J Ophthalmol"},{"key":"B9-20240828","doi-asserted-by":"crossref","first-page":"1428","DOI":"10.4103\/ijo.IJO_1854_18","article-title":"Rotation versus non-rotation of intraocular lens for prevention of posterior capsular opacification","volume":"67","author":"Joshi","year":"2019","journal-title":"Indian J Ophthalmol"},{"key":"B10-20240828","first-page":"45","article-title":"An Overview of Nd:YAG Laser Capsulotomy","volume":"3","author":"Karahan","year":"2014","journal-title":"Med Hypothesis Discov Innov Ophthalmol"},{"key":"B11-20240828","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1006\/exer.2001.1153","article-title":"Posterior capsule opacification:A cell biological perspective","volume":"74","author":"Wormstone","year":"2002","journal-title":"Exp Eye Res"},{"key":"B12-20240828","first-page":"1410","article-title":"Effect of cataract surgery on aqueous TGF-beta and lens epithelial cell proliferation","volume":"39","author":"Wallentin","year":"1998","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"B13-20240828","doi-asserted-by":"crossref","first-page":"1835","DOI":"10.1167\/iovs.11-8735","article-title":"Induction of posterior capsule opacification by hyaluronic acid in an ex vivo model","volume":"53","author":"Chandler","year":"2012","journal-title":"Investigative ophthalmol Vis Sci"},{"key":"B14-20240828","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1097\/ICU.0b013e3282f14db0","article-title":"Ophthalmic viscosurgical devices","volume":"19","author":"Bissen-Miyajima","year":"2008","journal-title":"Curr Opin Ophthalmol"},{"key":"B15-20240828","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/j.jcrs.2006.01.065","article-title":"Toxic anterior segment syndrome","volume":"32","author":"Mamalis","year":"2006","journal-title":"J Cataract Refract Surg"},{"key":"B16-20240828","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/0039-6257(92)90073-3","article-title":"Posterior capsule opacification","volume":"37","author":"Apple","year":"1992","journal-title":"Surv Ophthalmol"},{"key":"B17-20240828","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.jcrs.2009.10.042","article-title":"Hydroimplantation:Foldable intraocular lens implantation without an ophthalmic viscosurgical device","volume":"36","author":"Tak","year":"2010","journal-title":"J Cataract Refract Surg"},{"key":"B18-20240828","doi-asserted-by":"crossref","first-page":"47","DOI":"10.4103\/meajo.MEAJO_140_19","article-title":"Intraoperative evaluation of phacoemulsification cataract surgery with and without the use of ophthalmic viscosurgical devices","volume":"27","author":"Joshi","year":"2020","journal-title":"Middle East Afr J Ophthalmol"},{"key":"B19-20240828","doi-asserted-by":"crossref","first-page":"222","DOI":"10.3341\/kjo.2018.0122","article-title":"Comparison of the neodymium-doped yttrium aluminum garnet capsulotomy rate with viscoimplantation and the hydroimplantation intraocular lens technique","volume":"33","author":"O\u011furel","year":"2019","journal-title":"Korean J Ophthalmol"},{"key":"B20-20240828","doi-asserted-by":"crossref","first-page":"1627","DOI":"10.1016\/j.jcrs.2006.05.011","article-title":"Posterior capsule opacification after implantation of a hydrophilic or a hydrophobic acrylic intraocular lens:One-year follow-up","volume":"32","author":"Kugelberg","year":"2006","journal-title":"J Cataract Refract Surg"},{"key":"B21-20240828","doi-asserted-by":"crossref","first-page":"164","DOI":"10.5301\/ejo.5000831","article-title":"Posterior capsule opacification 9 years after phacoemulsification with a hydrophobic and a hydrophilic intraocular lens","volume":"27","author":"Chang","year":"2017","journal-title":"Eur J Ophthalmol"},{"key":"B22-20240828","doi-asserted-by":"crossref","first-page":"4566436","DOI":"10.1155\/2021\/4566436","article-title":"Long-term clinically significant posterior capsular opacification development pattern in eyes implanted with an aspheric monofocal intraocular lens with a square optic edge","volume":"2021","author":"Placeres Dab\u00e1n","year":"2021","journal-title":"J Ophthalmol"}],"container-title":["Indian Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijo.IJO_678_22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:10:29Z","timestamp":1787757029000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijo.IJO_678_22"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,30]]},"references-count":22,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4103\/ijo.ijo_678_22","relation":{},"ISSN":["0301-4738","1998-3689"],"issn-type":[{"value":"0301-4738","type":"print"},{"value":"1998-3689","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,30]]},"assertion":[{"value":"2022-03-15","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-07-13","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}