{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T18:59:21Z","timestamp":1790621961784,"version":"4.1.0"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:p>A 43-year-old male patient presented with acute blurring of vision in both eyes associated with photophobia, redness, and mild pain following coronavirus disease 2019 (Covid-19) infection. Clinical examination revealed extensive pigment dusting in the corneal endothelium and the trabecular meshwork with de-pigmentation bands in the iris periphery. The patient was managed empirically with topical anti-glaucoma medications for high intra-ocular pressure. The patient was prescribed systemic antibiotics including cephalosporins and amoxicillin for respiratory symptoms. A rare condition called bilateral acute de-pigmentation of iris (BADI) was suspected after ruling out common entities, for example, viral kerato-uveitis, pigment dispersion syndrome, and Fuchs iridocyclitis. Covid-19 infection and systemic antibiotics including cephalosporins have shown to cause BADI in the literature. The patient responded well with good outcome.<\/jats:p>","DOI":"10.4103\/ijo.ijo_75_22","type":"journal-article","created":{"date-parts":[[2022,8,4]],"date-time":"2022-08-04T11:45:11Z","timestamp":1659613511000},"page":"3136-3139","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":9,"title":["COVID-19-related bilateral acute de-pigmentation of iris with ocular hypertension"],"prefix":"10.4103","volume":"70","author":[{"given":"Sandhya","family":"Gaur","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Cornea Anterior Segment Services, Eye-Q Super Speciality Eye Hospitals, Gurugram, Haryana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Narottama","family":"Sindhu","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Cornea Anterior Segment Services, Eye-Q Super Speciality Eye Hospitals, Gurugram, Haryana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deependra Vikram","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Cornea Anterior Segment Services, Eye-Q Super Speciality Eye Hospitals, Gurugram, Haryana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mainak","family":"Bhattacharya","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Cornea Anterior Segment Services, Eye-Q Super Speciality Eye Hospitals, Gurugram, Haryana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajay","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Cornea Anterior Segment Services, Eye-Q Super Speciality Eye Hospitals, Gurugram, Haryana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dattatraya","family":"Shinde","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Cornea Anterior Segment Services, Eye-Q Super Speciality Eye Hospitals, Gurugram, Haryana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,7,29]]},"reference":[{"key":"B1-20240828","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1007\/s00417-005-0137-x","article-title":"Bilateral acute depigmentation of the iris","volume":"244","author":"Tugal-Tutkun","year":"2006","journal-title":"Graefe's Arch Clin Exp Ophthalmol"},{"key":"B2-20240828","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1080\/09273948.2021.1933073","article-title":"COVID-19 associated bilateral acute iris transillumination","volume":"29","author":"Yagci","year":"2021","journal-title":"Ocul Immunol Inflamm"},{"key":"B3-20240828","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1001\/archophthalmol.2011.310","article-title":"Bilateral acute iris transillumination","volume":"129","author":"Tugal-Tutkun","year":"2011","journal-title":"Arch Ophthalmol"},{"key":"B4-20240828","doi-asserted-by":"crossref","first-page":"2260","DOI":"10.1038\/eye.2009.234","article-title":"Uveitis-like syndrome and iris transillumination after the use of oral moxifloxacin","volume":"23","author":"Wefers","year":"2009","journal-title":"Eye (Lond)"},{"key":"B5-20240828","first-page":"357","article-title":"Acute and bilateral uveitis secondary to moxifloxacin","volume":"79","author":"Bringas","year":"2004","journal-title":"Arch Soc Esp Oftalmol"},{"key":"B6-20240828","doi-asserted-by":"crossref","first-page":"935","DOI":"10.2147\/OPTH.S167449","article-title":"Bilateral acute iris transillumination (BAIT) syndrome:Literature review","volume":"13","author":"Perone","year":"2019","journal-title":"Clin Ophthalmol"},{"key":"B7-20240828","doi-asserted-by":"crossref","first-page":"111","DOI":"10.3109\/15569527.2011.617024","article-title":"Bilateral uveitis associated with fluoroquinolone therapy","volume":"31","author":"Hinkle","year":"2012","journal-title":"Cutan Ocul Toxicol"},{"key":"B8-20240828","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1111\/j.1442-9071.2009.01920.x","article-title":"Pigment dispersion syndrome and pigmentary glaucoma--a major review","volume":"36","author":"Niyadurupola","year":"2008","journal-title":"Clin Exp Ophthalmol"},{"key":"B9-20240828","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1097\/00004397-200201000-00007","article-title":"Management of Herpetic Anterior Uveitis","volume":"42","author":"Siverio","year":"2002","journal-title":"International Ophthalmology Clinics:Winter"},{"key":"B10-20240828","first-page":"2515841418787988","article-title":"Bilateral acute depigmentation of iris\u202f:3-year follow-up of a case","volume":"10","author":"Atilgan","year":"2018","journal-title":"Ther Adv Ophthalmol"}],"container-title":["Indian Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijo.IJO_75_22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:07:47Z","timestamp":1787756867000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijo.IJO_75_22"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7,29]]},"references-count":10,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4103\/ijo.ijo_75_22","relation":{},"ISSN":["0301-4738","1998-3689"],"issn-type":[{"value":"0301-4738","type":"print"},{"value":"1998-3689","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,7,29]]},"assertion":[{"value":"2022-01-10","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-05-23","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}