{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T05:09:58Z","timestamp":1790140198375,"version":"4.0.1"},"reference-count":27,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"9","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To evaluate the gonioscopic changes in patients receiving Descemet\u2019s stripping endothelial keratoplasty (DSEK) without pre-existing ocular hypertension (OHT) and to report its correlation with post-surgery OHT, graft survival, and visual outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Adult patients who underwent DSEK surgery from April 2014 to March 2018 with at least 2 years of follow-up were analyzed in this retrospective study. Demographic details, indication of DSEK, necessary anterior and posterior segment findings, and the post-DSEK OHT details were documented.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>A total of 58 patients (23 males and 35 females) with a mean age of 61.44 \u00b1 8.8 years were included in the study. The most common etiology for DSEK surgery was pseudophakic bullous keratopathy in 47 eyes (81.03%). A total of 22.41% (13\/58) eyes showed elevated intra-ocular pressure (IOP) following DSEK surgery. The most common cause of IOP elevation was steroid-induced OHT in seven eyes (12.06%). Gonioscopy examination revealed areas of peripheral anterior synechiae (PAS) in 17 (29.3%) eyes. OHT was found in 4\/17 (23.5%) eyes having PAS. Three of these cases required trabeculectomy + goniosynechiolysis (GSL), and the fourth case required GSL alone to control IOP. These four cases also required repeat DSEK for failed grafts. The mean pre-operative best corrected visual acuity was 1.62 logMAR (range 1.17\u20131.77), which gradually improved to 0.79 logMAR (range 0.3\u20131.77) after 2 years (p &lt; 0.00001).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>PAS was found to be an important factor associated with post-DSEK ocular hypertension in our study. OHT in PAS cases required definitive surgical treatments to control IOP. It adversely affected the graft survival and in turn affected visual outcomes also.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_803_22","type":"journal-article","created":{"date-parts":[[2022,8,29]],"date-time":"2022-08-29T05:38:02Z","timestamp":1661751482000},"page":"3298-3034","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":4,"title":["Gonioscopic angle evaluation and its correlation with graft survival and post-operative ocular hypertension in patients of Descemet\u2019s stripping endothelial keratoplasty"],"prefix":"10.4103","volume":"70","author":[{"given":"Rakesh","family":"Shakya","sequence":"first","affiliation":[{"name":"Department of GlaucomaStrabismus, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Navjot Singh","family":"Ahluwalia","sequence":"additional","affiliation":[{"name":"Department of GlaucomaStrabismus, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chintan","family":"Shah","sequence":"additional","affiliation":[{"name":"Department of Pediatric Ophthalmology and Strabismus, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amit","family":"Mohan","sequence":"additional","affiliation":[{"name":"Department of Pediatric Ophthalmology and Strabismus, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gautam","family":"Parmar","sequence":"additional","affiliation":[{"name":"Department of Cornea and Refractive Services, Jankikund, Chitrakoot, Satna, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amit","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of GlaucomaStrabismus, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramesh K C","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of GlaucomaStrabismus, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prashant","family":"Borde","sequence":"additional","affiliation":[{"name":"Department of Cornea and Refractive Services, Jankikund, Chitrakoot, Satna, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B K","family":"Jain","sequence":"additional","affiliation":[{"name":"Quality Assurance, Sadguru Netra Chikitsalya and Postgraduate Institute of Ophthalmology, Jankikund, Chitrakoot, Satna, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,8,26]]},"reference":[{"key":"B1-20240828","doi-asserted-by":"crossref","first-page":"339","DOI":"10.3928\/1081-597X-20050701-07","article-title":"Descemet's stripping with endothelial keratoplasty in 50 eyes:A refractive neutral corneal 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