{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T18:58:03Z","timestamp":1785437883351,"version":"3.56.0"},"reference-count":22,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","license":[{"start":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T00:00:00Z","timestamp":1784764800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>This study aimed to investigate the relationship between contrast sensitivity (CS) and driving performance in individuals with moderate to severe glaucoma, using the Pelli\u2013Robson (PR) chart and Spaeth\/Richman Contrast Sensitivity (SPARCS) test.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>Cross-sectional observational study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods: Setting:<\/jats:title>\n                    <jats:p>A hospital-based study was conducted in a multi-specialty tertiary care institute.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Population:<\/jats:title>\n                    <jats:p>Forty-five non-professional drivers (90 eyes) diagnosed with moderate-to-severe glaucoma using Hodapp\u2013Anderson\u2013Parrish classification. Mean age (\u00b1 standard deviation, in years) was 61.76 \u00b1 10.02 with a significant male preponderance (97.8%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Observation Procedures:<\/jats:title>\n                    <jats:p>Participants underwent a comprehensive clinical assessment, and CS was assessed using both the PR chart and SPARCS. Driving-related parameters were evaluated using the Driving Habits Questionnaire, which assessed driving difficulty, driving space, and dependency on others. Statistical analyses were performed to identify correlations between CS scores and driving parameters.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Primary Outcome:<\/jats:title>\n                    <jats:p>Patients with lower peripheral contrast experienced significant driving-related difficulties.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Significant correlations were observed between CS and driving behaviors in the worse eye. Lower peripheral SPARCS scores (particularly upper and lower right quadrants; \u03c1 = 0.35\u20130.51,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05) were associated with reduced driving space (\u03c1 = 0.44\u20130.50) and increased dependency (\u03c1 = \u22120.32) and lower right scores (\n                      <jats:italic toggle=\"yes\">\u03c1<\/jats:italic>\n                      = \u22120.32,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.035). Driving difficulty scores showed positive correlations with SPARCS upper right quadrant (\n                      <jats:italic toggle=\"yes\">\u03c1<\/jats:italic>\n                      = 0.34,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.023) and lower right quadrant scores (\n                      <jats:italic toggle=\"yes\">\u03c1<\/jats:italic>\n                      = 0.51,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001). Driving space scores were positively correlated with PR (\n                      <jats:italic toggle=\"yes\">\u03c1<\/jats:italic>\n                      = 0.33,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.027) and total SPARCS scores.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>CS, especially in peripheral regions, is significantly associated with driving difficulties, reduced driving space, and dependency on others in individuals with glaucoma. The worse eye\u2019s CS measures have a stronger correlation with these driving-related factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical Implications:<\/jats:title>\n                    <jats:p>SPARCS correlates with structure and behavior, making it a holistic functional biomarker. Peripheral CS loss predicts functional self-regulation even before driving cessation. CS assessment could enhance the understanding of driving capabilities and safety, guide interventions, and driving restrictions more effectively to improve patient safety on the road.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_810_25","type":"journal-article","created":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T12:00:34Z","timestamp":1784894434000},"page":"1237-1243","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Impact of contrast sensitivity on driving behaviors in individuals with moderate-to-severe glaucoma"],"prefix":"10.4103","volume":"74","author":[{"given":"Navdeep","family":"Kaur","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Government Medical College and Hospital, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parul","family":"Ichhpujani","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Government Medical College and Hospital, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suresh","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Government Medical College and Hospital, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Varnika A","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Government Medical College and Hospital, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,7,23]]},"reference":[{"key":"R1-20260730","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1016\/j.jcrs.2013.05.001","article-title":"Contrast sensitivity basics and a critique of currently available tests","volume":"39","author":"Richman","year":"2013","journal-title":"J Cataract Refract Surg"},{"key":"R2-20260730","doi-asserted-by":"crossref","first-page":"2183","DOI":"10.1016\/S0140-6736(17)31469-1","article-title":"Glaucoma","volume":"390","author":"Jonas","year":"2017","journal-title":"Lancet"},{"key":"R3-20260730","doi-asserted-by":"crossref","first-page":"2081","DOI":"10.1016\/j.ophtha.2014.05.013","article-title":"Global prevalence of glaucoma and projections of glaucoma burden through 2040: A systematic review and meta-analysis","volume":"121","author":"Tham","year":"2014","journal-title":"Ophthalmology"},{"key":"R4-20260730","article-title":"Vision requirements for driving safety with emphasis on individual assessment","author":"Colenbrander","year":"2006","journal-title":"Report prepared for the International Council of Ophthalmology at the 30th World Ophthalmology Congress. 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