{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:21:45Z","timestamp":1787757705653,"version":"build-2784847793"},"reference-count":19,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To study the correlation between choroidal thickness (CT) and IOP control in primary angle-closure glaucoma (PACG).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>In total, 61 patients (102 eyes) with PACG underwent subfoveal CT (SFCT) scanning using enhanced depth imaging\u2013optical coherence tomography. The subjects with PACG were further grouped as controlled IOP (\u226421 mm Hg on maximal medical therapy) and uncontrolled IOP (&gt;21 mm Hg on maximal medical therapy). The average CT of the PACG eyes was calculated and compared between both groups. A correlation analysis was done between CT and intereye difference in CT with the disease parameters.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The mean CT was 274.38 \u00b1 42.10 \u03bcm in 102 PACG eyes. SFCT was significantly increased in the uncontrolled IOP group as compared with the controlled IOP group. The mean SFCT was 245.57 \u00b1 62.10 \u03bcm in the controlled group and 294.46 \u00b1 51.05 \u03bcm in the uncontrolled group (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.01). Factors associated with a thicker choroid were younger age, high IOP, and higher optic nerve head cupping (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001). Neither the visual field-mean deviation (VF-MD) nor pattern standard deviation (PSD) was found to be associated with overall CT. The intereye asymmetry between CT was significantly associated with poor VF-MD and PSD.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>PACG eyes with thicker choroid may be a risk factor for poor IOP control on medical anti-glaucoma therapy. Thicker choroid as compared to the fellow eye is a poor prognostic sign and these eyes should be monitored closely.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_824_21","type":"journal-article","created":{"date-parts":[[2021,12,27]],"date-time":"2021-12-27T06:00:43Z","timestamp":1640584843000},"page":"147-152","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":13,"title":["Correlation between choroidal thickness and intraocular pressure control in primary angle-closure glaucoma"],"prefix":"10.4103","volume":"70","author":[{"given":"Nishtha","family":"Singh","sequence":"first","affiliation":[{"name":"Department of Glaucoma, Dr. Shroff\u2019s Charity Eye Hospital, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"Pegu","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, Dr. Shroff\u2019s Charity Eye Hospital, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prerna","family":"Garg","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, Dr. Shroff\u2019s Charity Eye Hospital, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brajesh","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, Dr. Shroff\u2019s Charity Eye Hospital, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suneeta","family":"Dubey","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, Dr. Shroff\u2019s Charity Eye Hospital, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica","family":"Gandhi","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, Dr. Shroff\u2019s Charity Eye Hospital, New Delhi, 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