{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T18:29:33Z","timestamp":1792693773231,"version":"4.5.0"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:p>Surgical placement of eye plaque brachytherapy (EPB) is the standard of care for the treatment of uveal melanomas, including iris\/iridociliary melanomas. However, unique challenges exist in anterior EPB placement. Here, we describe a surgical technique for anterior EPB placement when placement requires plaque positioning onto the cornea. Blunt conjunctival peritomy exposes the sclera overlying the tumor. A \u201cdummy\u201d plaque is placed, with positioning confirmed by direct visualization. The amniotic membrane is draped across the cornea and anchored with the eyelet sutures, the plaque is placed overlying the membrane, the conjunctiva is closed over the plaque, and a temporary tarsorrhaphy is performed. One week later, the conjunctival incision is reopened for plaque\/amniotic membrane removal. This technique was employed in the treatment of 12 iris\/iridociliary melanomas at our institution, with no instances of corneal damage. In placing an anterior plaque, employing this technique allows appropriate cancer treatment while optimizing patient comfort and corneal integrity.<\/jats:p>","DOI":"10.4103\/ijo.ijo_824_23","type":"journal-article","created":{"date-parts":[[2024,1,8]],"date-time":"2024-01-08T10:01:03Z","timestamp":1704708063000},"page":"912-915","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Anterior plaque brachytherapy placement for treatment of iris and iridociliary melanomas \u2013 Surgical procedure and institutional experience"],"prefix":"10.4103","volume":"72","author":[{"given":"Sarah","family":"Pike","sequence":"first","affiliation":[{"name":"USC Roski Eye Institute, Keck School of Medicine of USC, Los Angeles, CA, USA"},{"name":"The Vision Center, Children\u2019s Hospital Los Angeles, Los Angeles, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie B","family":"Engelhard","sequence":"additional","affiliation":[{"name":"USC Roski Eye Institute, Keck School of Medicine of USC, Los Angeles, CA, USA"},{"name":"The Vision Center, Children\u2019s Hospital Los Angeles, Los Angeles, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luciano Custo","family":"Greig","sequence":"additional","affiliation":[{"name":"USC Roski Eye Institute, Keck School of Medicine of USC, Los Angeles, CA, USA"},{"name":"The Vision Center, Children\u2019s Hospital Los Angeles, Los Angeles, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaley","family":"Woods","sequence":"additional","affiliation":[{"name":"Radiation Oncology, Keck School of Medicine of USC, Los Angeles, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard L","family":"Jennelle","sequence":"additional","affiliation":[{"name":"Radiation Oncology, Keck School of Medicine of USC, Los Angeles, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jesse L","family":"Berry","sequence":"additional","affiliation":[{"name":"USC Roski Eye Institute, Keck School of Medicine of USC, Los Angeles, CA, USA"},{"name":"The Vision Center, Children\u2019s Hospital Los Angeles, Los Angeles, CA, USA"},{"name":"Radiation Oncology, Keck School of Medicine of USC, Los Angeles, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,1,8]]},"reference":[{"key":"R1-20260504","doi-asserted-by":"crossref","first-page":"46","DOI":"10.5114\/jcb.2021.103586","article-title":"Plaque brachytherapy in iris and iridociliary melanoma: A systematic review of efficacy and complications","volume":"13","author":"Karimi","year":"2021","journal-title":"J Contemp Brachytherapy"},{"key":"R2-20260504","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.jaapos.2011.10.012","article-title":"Iris melanoma: Features and prognosis in 317 children and adults","volume":"16","author":"Shields","year":"2012","journal-title":"J AAPOS"},{"key":"R3-20260504","doi-asserted-by":"crossref","first-page":"925","DOI":"10.2147\/OPTH.S129645","article-title":"Brachytherapy for patients with uveal melanoma: Historical perspectives and future treatment directions","volume":"12","author":"Brewington","year":"2018","journal-title":"Clin Ophthalmol"},{"key":"R4-20260504","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1136\/bjo.79.4.306","article-title":"Treatment of non-resectable malignant iris tumours with custom designed plaque radiotherapy","volume":"79","author":"Shields","year":"1995","journal-title":"Br J Ophthalmol"},{"key":"R5-20260504","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1159\/000493269","article-title":"Novel eye plaque designs for brachytherapy of iris and ciliary body melanoma and the first clinical application","volume":"5","author":"Liu","year":"2019","journal-title":"Ocul Oncol Pathol"},{"key":"R6-20260504","doi-asserted-by":"crossref","first-page":"866","DOI":"10.3928\/23258160-20150909-12","article-title":"Use of the toric surgical marker to aid in intraoperative plaque placement for the USC eye physics plaques to treat uveal melanoma: A new surgical technique","volume":"46","author":"Berry","year":"2015","journal-title":"Ophthalmic Surg Lasers Imaging Retina"},{"key":"R7-20260504","first-page":"1","article-title":"The American Brachytherapy Society consensus guidelines for plaque brachytherapy of uveal melanoma and retinoblastoma","volume":"13","year":"2014","journal-title":"Brachytherapy"},{"key":"R8-20260504","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1001\/archopht.126.4.531","article-title":"Finger\u2019s amniotic membrane buffer technique: Protecting the cornea during radiation plaque therapy","volume":"126","author":"Finger","year":"2008","journal-title":"Arch 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Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/IJO.IJO_824_23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:40:21Z","timestamp":1786650021000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/IJO.IJO_824_23"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,8]]},"references-count":10,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/ijo.ijo_824_23","relation":{},"ISSN":["0301-4738","1998-3689"],"issn-type":[{"value":"0301-4738","type":"print"},{"value":"1998-3689","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1,8]]},"assertion":[{"value":"2023-03-28","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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