{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T12:55:04Z","timestamp":1788353704338,"version":"build-2803163510"},"reference-count":41,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"12","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To evaluate the safety and efficacy of ultrasound cycloplasty in eyes with primary or secondary open-angle glaucoma, not amenable to adequate control of intra-ocular pressure (IOP) with medical treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Prospective interventional cohort study of 28 eyes of 28 subjects in a tertiary eye care centre in India in patients with open-angle glaucoma. All enrolled eyes underwent ultrasound cycloplasty with the second-generation probe with six shots of 8 s each, operated by a single surgeon between November 2018 and January 2020. They were followed up for a period of 12 months. The primary treatment outcome was IOP and the secondary outcomes were vision and postoperative complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      A total of 28 eyes of 28 patients were studied, and the mean age was 63.82 \u00b1 6.46 years. Primary open-angle glaucoma (75%) was the most common etiology. There was significant reduction in IOP from the baseline (24.93 \u00b1 4.27 mmHg) to the postoperative value (15.82 \u00b1 3.14 mmHg) at the end of 12 months (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.00001). Mean reduction in IOP was 9.14 \u00b1 4.09 mmHg at 12 months (36.66%). Number of ocular hypotensives reduced significantly from baseline (3.32 \u00b1 0.47) to 12-month postoperative follow-up (0.68 \u00b1 0.74) (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.00001). Qualified success was achieved in 89.28% eyes. No major complications were noted.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Ultrasound cycloplasty is found to be effective and safe in eyes with open-angle glaucoma because of the primary or secondary etiology, being more effective in the former.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijo.ijo_827_22","type":"journal-article","created":{"date-parts":[[2022,12,6]],"date-time":"2022-12-06T08:53:31Z","timestamp":1670316811000},"page":"4168-4171","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":6,"title":["Efficacy and safety of ultrasound cycloplasty in Indian eyes with open-angle glaucoma"],"prefix":"10.4103","volume":"70","author":[{"given":"Chandrima","family":"Paul","sequence":"first","affiliation":[{"name":"Director, B B Eye Foundation, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Divya","sequence":"additional","affiliation":[{"name":"Fellow, Comprehensive Ophthalmology, B B Eye Foundation, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Subhrangshu","family":"Sengupta","sequence":"additional","affiliation":[{"name":"Centre for Sight, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richa","family":"Kamal","sequence":"additional","affiliation":[{"name":"Vitreo-Retina Services, B B Eye Foundation, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anujeet","family":"Paul","sequence":"additional","affiliation":[{"name":"Mahatma Gandhi Medical College and Research Institute, Pondicherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ishani","family":"Mitra","sequence":"additional","affiliation":[{"name":"Fortis Hospital, Bangalore, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,11,30]]},"reference":[{"key":"R1-20251006","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1001\/archopht.122.4.477","article-title":"Causes and prevalence of visual impairment among adults in the United States","volume":"122","author":"Congdon","year":"2004","journal-title":"Arch Ophthalmol"},{"key":"R2-20251006","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1136\/bjo.2005.067355","article-title":"Direct costs of glaucoma and severity of the disease:A multinational long-term study of resource utilisation in Europe","volume":"89","author":"TraversoCE, Walt","year":"2005","journal-title":"Br J Ophthalmol"},{"key":"R4-20251006","doi-asserted-by":"crossref","first-page":"108506","DOI":"10.1016\/j.exer.2021.108506","article-title":"Protection of retinal ganglion cells in glaucoma:Current status and future","volume":"205","author":"Shen","year":"2021","journal-title":"Exp Eye Res"},{"key":"R5-20251006","first-page":"189","article-title":"Cryosurgery for the treatment of glaucoma","volume":"63","author":"De Roetth","year":"1965","journal-title":"Trans Am Ophthalmol Soc"},{"key":"R6-20251006","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0161-6420(90)32640-4","article-title":"Choroidal detachment, flat anterior chamber, and hypotony as complications of neodymium:YAG laser cyclophotocoagulation","volume":"97","author":"Maus","year":"1990","journal-title":"Ophthalmology"},{"key":"R7-20251006","doi-asserted-by":"crossref","first-page":"1823","DOI":"10.1016\/S0161-6420(92)31718-X","article-title":"Ophthalmic laser microendoscope ciliary process ablation in the management of neovascular glaucoma","volume":"99","author":"Uram","year":"1992","journal-title":"Ophthalmology"},{"key":"R8-20251006","first-page":"526","article-title":"Transscleral neodymium:YAG laser cyclophotocoagulation for end-stage glaucoma, refractory glaucoma, and painful blind eyes","volume":"24","author":"Al-Ghamdi","year":"1993","journal-title":"Ophthalmic Surg"},{"key":"R9-20251006","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1016\/S0161-6420(96)30508-3","article-title":"Longterm outcome of initial ciliary ablation with contact diode laser transscleral cyclophotocoagulation for severe glaucoma. 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