{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T07:50:28Z","timestamp":1791359428316,"version":"4.3.1"},"reference-count":19,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"10","license":[{"start":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:00:00Z","timestamp":1790640000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,10]]},"abstract":"\n Purpose:<\/jats:title>\n To analyze the patient characteristics, initial outcomes, and complications associated with iStent implantation in Indian eyes.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n This retrospective case series comprised subjects who underwent iStent, iStent inject, or iStent inject W implantation as a standalone procedure or combined with phacoemulsification with at least 12 months follow-up. The main outcome measures were change in intraocular pressure (IOP) and number of anti-glaucoma medication (AGM), post op complications, and resurgery rates at the final follow-up.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n A total of 56 eyes of 46 patients were included. Twenty-six eyes received iStent, and 30 eyes received either iStent inject or iStent inject W. Mean IOP reduced by 25.5%, and the mean number of AGM decreased by 75.8% at final follow-up (\n P<\/jats:italic>\n < 0.005). The overall success rate was achieved in 51 eyes (85%). When compared to standalone iStent, combined phacoemulsification with iStent delivered greater reduction in AGM (\n P<\/jats:italic>\n = 0.004). Compared to iStent, eyes with iStent inject and inject W had better IOP reduction (\n P<\/jats:italic>\n = 0.03), lesser AGM (\n P<\/jats:italic>\n < 0.005), and a lesser number of surgical failures (\n P<\/jats:italic>\n = 0.045). Three months after iStent inject implantation, trabeculectomy was performed in one eye with secondary glaucoma. Postoperative IOP rise due to steroid response was observed in 20 eyes (35.7%).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n iStent implantation in Indian eyes demonstrated promising outcomes in reducing both intraocular pressure and anti-glaucoma medication burden. While combined procedures exhibited superior efficacy in reducing IOP and AGM, postoperative complications such as steroid-induced IOP rise were observed, emphasizing the importance of careful monitoring and management in optimizing surgical outcomes.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/ijo.ijo_981_25","type":"journal-article","created":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T14:04:13Z","timestamp":1790690653000},"page":"1473-1477","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Retrospective analysis of indications and outcomes of trabecular micro-bypass stent implantation in Indian eyes"],"prefix":"10.4103","volume":"74","author":[{"given":"Amit","family":"Pandey","sequence":"first","affiliation":[{"name":"Medical City for Military and Security Services, AlKhoudh, Muscat, Oman"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harsh","family":"Kumar","sequence":"additional","affiliation":[{"name":"Centre for Sight Eye Hospital, Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhishek","family":"Kathuria","sequence":"additional","affiliation":[{"name":"Centre for Sight Eye Hospital, Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sagarika","family":"Patyal","sequence":"additional","affiliation":[{"name":"Centre for Sight Eye Hospital, Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Swati","family":"Singh","sequence":"additional","affiliation":[{"name":"Centre for Sight Eye Hospital, Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bhavini","family":"Pandey","sequence":"additional","affiliation":[{"name":"Medical City for Military and Security Services, AlKhoudh, Muscat, Oman"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,9,29]]},"reference":[{"key":"R1-20261007","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1136\/bjo.2005.081224","article-title":"The number of people with glaucoma worldwide in 2010 and 2020","volume":"90","author":"Quigley","year":"2006","journal-title":"Br J Ophthalmol"},{"key":"R2-20261007","doi-asserted-by":"crossref","first-page":"1418","DOI":"10.4103\/ijo.IJO_2008_20","article-title":"An exploratory study of compliance to anti-glaucoma medications among literate primary glaucoma patients at an urban tertiary eye care center in South India","volume":"69","author":"Ramesh","year":"2021","journal-title":"Indian J Ophthalmol"},{"key":"R3-20261007","doi-asserted-by":"crossref","first-page":"1308","DOI":"10.1016\/j.ophtha.2015.03.026","article-title":"The most common barriers to glaucoma medication adherence: A cross sectional 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phacoemulsification alone","volume":"232","author":"El Wardani","year":"2015","journal-title":"Klin Monbl Augenheilkd"},{"key":"R11-20261007","first-page":"231320","article-title":"Prospective, randomized study of one, two, or three trabecular bypass stents in openangle glaucoma subjects on topical hypotensive medication","volume":"9","author":"Katz","year":"2015","journal-title":"Clin Ophthalmol"},{"key":"R12-20261007","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.1007\/s12325-024-02788-y","article-title":"7-year efficacy and safety of iStent inject trabecular micro-bypass in combined and standalone usage","volume":"41","author":"Hengerer","year":"2024","journal-title":"Adv Ther"},{"key":"R13-20261007","first-page":"875","article-title":"Prospective unmasked randomized evaluation of the iStent inject versus two ocular hypotensive agents in patients with primary open angle glaucoma","volume":"8","author":"Fea","year":"2021","journal-title":"Clin 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severities","volume":"8","author":"Salimi","year":"2019","journal-title":"Ophthalmol Ther"}],"container-title":["Indian Journal of 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