{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T13:37:07Z","timestamp":1790775427156,"version":"4.1.0"},"reference-count":24,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Ionizing radiation is well known to cause oxidative stress which is responsible for various health hazards. Controlling healthcare workers' exposure and raising attention toward continuous monitoring is the first step for improving both the health of healthcare workers and the quality of patient care, thus decreasing both human and economic costs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>To assess oxidative stress by measuring the level of lipid peroxidation, antioxidants, and measure complete blood count (CBC) among healthcare workers exposed to ionizing radiation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A cross-sectional study conducted at the diagnostic radiology department on 31 healthcare workers exposed to ionizing radiation and a non-exposed group of 31 healthcare workers from outpatient clinics. Malondialdehyde (MDA), superoxide dismutase (SOD), and CBC were measured among both groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>MDA was significantly higher among the exposed group, while the level of SOD was significantly lower. Red blood cells and hemoglobin were significantly lower among the exposed group. The most significant predictor of oxidative stress was the duration of work.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Ionizing radiation exposure induce oxidative stress which has an important role in radiation-related health effects. Anemia was the most common hematological health hazards among the exposed group.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijoem.ijoem_198_20","type":"journal-article","created":{"date-parts":[[2024,1,4]],"date-time":"2024-01-04T07:23:34Z","timestamp":1704353014000},"page":"72-77","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":16,"title":["Healthcare Workers Exposure to Ionizing Radiation"],"prefix":"10.4103","volume":"25","author":[{"given":"Sarah A.","family":"Bolbol","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mona F.","family":"Zaitoun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sahar A.","family":"Abou El-Magd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noha A.","family":"Mohammed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R3-5-20240902","first-page":"1","article-title":"Radiation-induced normal tissue damage: Oxidative stress and epigenetic mechanisms","volume":"2019","author":"Wei","year":"2019","journal-title":"Oxid Med Cell Longev"},{"key":"R4-5-20240902","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1080\/09553002.2019.1571255","article-title":"Chronic low dose exposure of hospital workers to ionizing radiation leads to increased micronuclei frequency and reduced antioxidants in their peripheral blood lymphocytes","volume":"95","author":"Siama","year":"2019","journal-title":"Int J Radiat Biol"},{"key":"R5-5-20240902","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2019\/1279250","article-title":"Approaches and methods to measure oxidative stress in clinical samples: Research applications in the cancer field","volume":"2019","author":"Katerji","year":"2019","journal-title":"Oxid Med Cell Longev"},{"key":"R6-5-20240902","doi-asserted-by":"crossref","first-page":"379","DOI":"10.2754\/avb201887040379","article-title":"The effect of curcumin on lipid peroxidation and selected antioxidants in irradiated rats","volume":"87","author":"Ozcelik","year":"2019","journal-title":"Acta Veterinaria Brno"},{"key":"R7-5-20240902","doi-asserted-by":"crossref","first-page":"62","DOI":"10.21608\/ejhm.2020.67678","article-title":"Protective role of royal jelly against gamma radiation induced oxidative stress, cardio-toxicity and organ dysfunctions in male rats","volume":"78","author":"Sarhan","year":"2020","journal-title":"Egypt J Hosp Med"},{"key":"R8-5-20240902","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/S0076-6879(78)52032-6","article-title":"Microsomal lipid peroxidation","volume":"52","author":"Buege","year":"1978","journal-title":"Methods Enzymol"},{"key":"R9-5-20240902","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1093\/clinchem\/43.7.1209","article-title":"Plasma malondialdehyde as biomarker for oxidative stress: Reference interval and effects of life-style factors","volume":"43","author":"Nielsen","year":"1997","journal-title":"Clin Chem"},{"key":"R10-5-20240902","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/0003-2697(82)90214-7","article-title":"Standardized method for the determination of human erythrocyte membrane adenosine triphosphatases","volume":"124","author":"Reinila","year":"1982","journal-title":"Anal Biochem"},{"key":"R11-5-20240902","first-page":"130","article-title":"A modified spectrophotometric assay of superoxide dismutase","volume":"21","author":"Kakkar","year":"1984","journal-title":"Indian J Biochem Biophys"},{"key":"R12-5-20240902","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/0022-1759(90)90075-7","article-title":"Serum-manganese-superoxide dismutase: Normal values and increased levels in patients with acute myocardial infarction and several malignant diseases determined by an enzyme-linked immunosorbent assay using a monoclonal antibody","volume":"127","author":"Kawaguchi","year":"1990","journal-title":"J Immunol Methods"},{"key":"R13-5-20240902","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1177\/1559325818796331","article-title":"Health impacts of low-dose ionizing radiation: Current scientific debates and regulatory issues","volume":"16","author":"Vaiserman","year":"2018","journal-title":"Dose-Response"},{"key":"R14-5-20240902","first-page":"LC07","article-title":"Knowledge of radiation hazards, radiation protection practices and clinical profile of health workers in a teaching hospital in northern Nigeria","volume":"10","author":"Awosan","year":"2016","journal-title":"J Clin Diagn Res"},{"key":"R15-5-20240902","first-page":"126","article-title":"Annual effective dose status among the radiation staff of Lagos university teaching hospital, Lagos, Nigeria","volume":"3","author":"Ibitoye","year":"2011","journal-title":"Afr J Basic Appl"},{"key":"R16-5-20240902","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1088\/0952-4746\/23\/2\/307","article-title":"Whole-body doses of occupationally exposed female workers in Nigeria (1999\u20132001)","volume":"23","author":"Ogundare","year":"2003","journal-title":"J Radiol Prot"},{"key":"R17-5-20240902","first-page":"1535","article-title":"Ionizing radiation Hazards and protection practices among radiographers at Cairo University Hospitals","volume":"85","author":"Mohammed","year":"2017","journal-title":"Med J Cairo Univ"},{"key":"R18-5-20240902","doi-asserted-by":"crossref","first-page":"35","DOI":"10.18410\/jebmh\/2019\/6","article-title":"Haematological profile in radiographers exposed to low dose radiation","volume":"6","author":"Pramila","year":"2019","journal-title":"J Evid Based Med Healthc"},{"key":"R19-5-20240902","first-page":"38","article-title":"Hematological profile change in radiation field workers","volume":"1","author":"Davoudi","year":"2012","journal-title":"Apadana J Clin Res"},{"key":"R20-5-20240902","first-page":"1335","article-title":"At Biophysics Department, Faculty of Science, Cairo University to assess the health risks for medical radiation workers in the field of nuclear medicine and radiotherapy","volume":"86","author":"El-zayat","year":"2010","journal-title":"Med J Cairo Univ"},{"key":"R21-5-20240902","first-page":"249","article-title":"Chromosomal aberrations and oxidative DNA adduct 8-hydroxy-2-deoxyguanosine as biomarkers of radiotoxicity in radiation workers","volume":"9","author":"El-Benhawy","year":"2016","journal-title":"J Radiat Res Appl Sci"},{"key":"R22-5-20240902","first-page":"9","article-title":"Erythrocyte antioxidant parameters in workers occupationally exposed to low levels of ionizing radiation","volume":"15","author":"K\u0142ucinski","year":"2008","journal-title":"Ann Agric Environ Med"},{"key":"R23-5-20240902","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1177\/1091581815625593","article-title":"Genetic instability in lymphocytes is associated with blood plasma antioxidant levels in health care workers occupationally exposed to ionizing radiation","volume":"35","author":"Kumar","year":"2016","journal-title":"Int J Toxicol"},{"key":"R24-5-20240902","doi-asserted-by":"crossref","first-page":"12","DOI":"10.3390\/antiox8010012","article-title":"Healthcare workers occupationally exposed to ionizing radiation exhibit altered levels of inflammatory cytokines and redox parameters","volume":"8","author":"Ahmad","year":"2019","journal-title":"Antioxidants"},{"key":"R25-5-20240902","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.pnpbp.2009.01.001","article-title":"Correlation between lipid peroxidation-induced TBARS level and disease severity in obsessive\u2013compulsive disorder","volume":"33","author":"Chakraborty","year":"2009","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"R26-5-20240902","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1177\/1559325819891378","article-title":"Assessment of genomic instability in medical workers exposed to chronic low-dose X-Rays in Northern China","volume":"17","author":"Fang","year":"2019","journal-title":"Dose-Response"}],"container-title":["Indian Journal of Occupational and Environmental Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijoem.IJOEM_198_20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:58:03Z","timestamp":1787763483000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijoem.IJOEM_198_20"}},"subtitle":["Oxidative Stress and Antioxidant Response"],"short-title":[],"issued":{"date-parts":[[2021,4]]},"references-count":24,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.4103\/ijoem.ijoem_198_20","relation":{},"ISSN":["0973-2284"],"issn-type":[{"value":"0973-2284","type":"print"}],"subject":[],"published":{"date-parts":[[2021,4]]}}}