{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T15:02:52Z","timestamp":1791903772585,"version":"4.3.4"},"reference-count":40,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,5]]},"abstract":"\n Background:<\/jats:title>\n The heterogenic manifestations of polycystic ovarian syndrome have led to various treatment approaches that include improving hormonal imbalance, weight management, and improving quality of life (QoL). Yoga therapy being a versatile treatment approach benefits physical and mental well-being and can be recommended to women with polycystic ovary syndrome (PCOS).<\/jats:p>\n <\/jats:sec>\n \n Objective:<\/jats:title>\n The objective of this study was to study the effect of structured yoga intervention on anthropometric, metabolic, hormonal, biochemical, ovarian morphology, and infertility-related QoL parameters among infertile women with PCOS.<\/jats:p>\n <\/jats:sec>\n \n Settings and Design:<\/jats:title>\n A prospective, controlled before and after study was conducted at a Multidisciplinary PCOS Clinic in Mumbai, Maharashtra, India.<\/jats:p>\n <\/jats:sec>\n \n Methodology:<\/jats:title>\n Infertile women with PCOS (26 participants in each group which includes intervention and control arm) seeking treatment for infertility at the Multidisciplinary PCOS Clinic at National Institute for Research in Reproductive and Child Health. The intervention group received 90 min of structured yoga intervention for 3 months.<\/jats:p>\n <\/jats:sec>\n \n Statistical Analysis:<\/jats:title>\n The median change in parameters between baseline and after 12 weeks of intervention was analyzed using IBM SPSS software, version 26 to perform descriptive analyses and Wilcoxon test to analyze pre- and postintervention parameters in the intervention and control group.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n There was a significant difference in the weight, basal metabolic rate, postglucose insulin, anti-M\u00fcllerian hormone, cholesterol, high-density lipoprotein, low-density lipoprotein, serum glutamic pyruvic transaminase, ultrasound parameters such as stromal thickness, follicle number per ovary, and QoL in infertility domain in the intervention group compared to the control group. Within 1 year of initiation of the study, 13 participants became pregnant in the yoga intervention group as compared to 7 participants in the control group.<\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n The metabolic comorbidities of PCOS have adverse effects on the QoL and pregnancy outcome among infertile women with PCOS. This pilot study demonstrated that a 12-week yoga intervention brought overall improvement in anthropometric, hormonal, biochemical, ovarian morphology, and infertility-related QoL parameters compared to the control group. Integration of yoga in infertility management will help to improve the QoL and to optimize prepregnancy metabolic parameters among infertile women with PCOS.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/ijoy.ijoy_88_23","type":"journal-article","created":{"date-parts":[[2024,5,31]],"date-time":"2024-05-31T06:03:59Z","timestamp":1717135439000},"page":"98-105","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":11,"title":["Yoga Intervention Improves the Metabolic Parameters and Quality of Life among Infertile Women with Polycystic Ovary Syndrome in Indian Population"],"prefix":"10.4103","volume":"16","author":[{"given":"Anushree Devashish","family":"Patil","sequence":"first","affiliation":[{"name":"Department of Clinical Research, ICMR-National Institute for Research in Reproductive Health, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satish Dattatray","family":"Pathak","sequence":"additional","affiliation":[{"name":"Department of Scientific Research, Kaivalyadhama Yoga Institute and Research Center, College of Yoga, Lonavala, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pratibha","family":"Kokate","sequence":"additional","affiliation":[{"name":"Department of Clinical Research, ICMR-National Institute for Research in Reproductive Health, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ranjit Singh","family":"Bhogal","sequence":"additional","affiliation":[{"name":"Department of Scientific Research, Kaivalyadhama Yoga Institute and Research Center, Lonavala, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akshata Sudesh","family":"Badave","sequence":"additional","affiliation":[{"name":"Kaivalyadhama Yoga Institute and Research Center, Lonavala, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mangalam","family":"Varadha","sequence":"additional","affiliation":[{"name":"Department of Clinical Research, ICMR-National Institute for Research in Reproductive Health, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beena Nitin","family":"Joshi","sequence":"additional","affiliation":[{"name":"Department of Operational Research, ICMR-National Institute for Research in Reproductive Health, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepti","family":"Tandon","sequence":"additional","affiliation":[{"name":"Department of Clinical Research, ICMR-National Institute for Research in Reproductive Health, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shahina","family":"Begum","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, ICMR-National Institute for Research in Reproductive and Child Health, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suchitra Vishwambar","family":"Surve","sequence":"additional","affiliation":[{"name":"Department of Child Health Research, ICMR-National Institute for Research in Reproductive and Child Health, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prachi Datta","family":"Dalvi","sequence":"additional","affiliation":[{"name":"Department of Swasthavrutta, B. R. Harane Ayurvedic Medical College, Thane, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,11,21]]},"reference":[{"key":"R1-20260512","doi-asserted-by":"crossref","first-page":"261","DOI":"10.4103\/jhrs.JHRS_95_18","article-title":"The prevalence of polycystic ovary syndrome: A brief systematic review","volume":"13","author":"Deswal","year":"2020","journal-title":"J Hum Reprod Sci"},{"key":"R2-20260512","doi-asserted-by":"crossref","first-page":"333","DOI":"10.4103\/ijmr.IJMR_1937_17","article-title":"Epidemiology, pathogenesis, genetics and management of polycystic ovary syndrome in India","volume":"150","author":"Ganie","year":"2019","journal-title":"Indian J Med Res"},{"key":"R3-20260512","doi-asserted-by":"crossref","first-page":"516","DOI":"10.3389\/fendo.2020.00516","article-title":"Fundamental concepts and novel aspects of polycystic ovarian syndrome: Expert consensus resolutions","volume":"11","author":"Aversa","year":"2020","journal-title":"Front Endocrinol (Lausanne)"},{"key":"R4-20260512","doi-asserted-by":"crossref","first-page":"659","DOI":"10.18203\/2320-1770.ijrcog20200354","article-title":"Assessment of depression, anxiety and stress among Indian infertile couples in a tertiary health care centre in Bihar","volume":"9","author":"Singh","year":"2020","journal-title":"Int J Reprod Contracept Obstet Gynecol"},{"key":"R5-20260512","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1007\/s40279-014-0291-6","article-title":"Mental health and physical activity in women with polycystic ovary syndrome: A brief review","volume":"45","author":"Conte","year":"2015","journal-title":"Sports Med"},{"key":"R6-20260512","doi-asserted-by":"crossref","first-page":"1510","DOI":"10.1017\/S0033291718002076","article-title":"Depression, anxiety and perceived stress in women with and without PCOS: A community-based study","volume":"49","author":"Damone","year":"2019","journal-title":"Psychol Med"},{"key":"R7-20260512","doi-asserted-by":"crossref","first-page":"709674","DOI":"10.3389\/fpsyt.2021.709674","article-title":"The prevalence and factors associated with anxiety-like and depression-like behaviors in women with polycystic ovary syndrome","volume":"12","author":"Lin","year":"2021","journal-title":"Front Psychiatry"},{"key":"R8-20260512","doi-asserted-by":"crossref","first-page":"5801","DOI":"10.1210\/jc.2003-030562","article-title":"Quality of life, psychosocial well-being, and sexual satisfaction in women with polycystic ovary syndrome","volume":"88","author":"Elsenbruch","year":"2003","journal-title":"J Clin Endocrinol Metab"},{"key":"R9-20260512","first-page":"45","article-title":"Yoga therapy: The fourth dimension in the multidisciplinary management of women with polycystic ovary syndrome, a narrative review","volume":"71","author":"Anushree","year":"2018","journal-title":"Indian Pract"},{"key":"R10-20260512","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.urology.2003.09.015","article-title":"Impact of infertility on quality of life, marital adjustment, and sexual function","volume":"63","author":"Monga","year":"2004","journal-title":"Urology"},{"key":"R11-20260512","doi-asserted-by":"crossref","first-page":"2251","DOI":"10.1093\/humrep\/deh432","article-title":"Infertility caused by PCOS \u2013 Health-related quality of life among Austrian and Moslem immigrant women in Austria","volume":"19","author":"Schmid","year":"2004","journal-title":"Hum Reprod"},{"key":"R12-20260512","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1007\/s10730-011-9159-4","article-title":"Emotions and ethical considerations of women undergoing IVF-treatments","volume":"23","author":"Kaliarnta","year":"2011","journal-title":"HEC Forum"},{"key":"R13-20260512","article-title":"Yoga as a tool in peace education","author":"Gandhi"},{"key":"R14-20260512","doi-asserted-by":"crossref","first-page":"e212","DOI":"10.1002\/hsr2.212","article-title":"Impact of yoga and exercises on polycystic ovarian syndrome risk among adolescent schoolgirls in South India","volume":"3","author":"Selvaraj","year":"2020","journal-title":"Health Sci Rep"},{"key":"R15-20260512","first-page":"5","article-title":"Effect of yoga on metabolic syndrome","author":"Das","year":"2015","journal-title":"International Journal of Scientific and Research Publications"},{"key":"R16-20260512","doi-asserted-by":"crossref","first-page":"103","DOI":"10.4103\/ijoy.IJOY_46_16","article-title":"Yoga practice improves the body mass index and blood pressure: A randomized controlled trial","volume":"10","author":"Chauhan","year":"2017","journal-title":"Int J Yoga"},{"key":"R17-20260512","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1177\/15598276211029221","article-title":"Effect of yoga therapy on health outcomes in women with polycystic ovary syndrome: A systematic review and meta-analysis","volume":"17","author":"Verma","year":"2023","journal-title":"Am J Lifestyle Med"},{"key":"R18-20260512","first-page":"18","article-title":"The effect of six weeks yoga exercises on quality of life in infertile women with polycystic ovary syndrome (PCOS)","volume":"22","author":"Bahrami","year":"2019","journal-title":"Iran J Obstet Gynecol Infertil"},{"key":"R19-20260512","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.4158\/EP15748.DSCPT2","article-title":"American association of clinical endocrinologists, American college of endocrinology, and androgen excess and PCOS society disease state clinical review: Guide to the best practices in the evaluation and treatment of polycystic ovary syndrome \u2013 Part 2","volume":"21","author":"Goodman","year":"2015","journal-title":"Endocr Pract"},{"key":"R20-20260512","first-page":"32","article-title":"Narrative review of yoga intervention clinical trials including weight-related outcomes","volume":"19","author":"Rioux","year":"2013","journal-title":"Altern Ther Health Med"},{"key":"R21-20260512","doi-asserted-by":"crossref","first-page":"27","DOI":"10.4103\/0973-6131.36761","article-title":"Long-term effect of yogic practices on diurnal metabolic rates of healthy subjects","volume":"1","author":"Chaya","year":"2008","journal-title":"Int J Yoga"},{"key":"R22-20260512","first-page":"29","article-title":"Energy expenditure and ventilatory responses during Siddhasana \u2013 A yogic seated posture","volume":"38","author":"Rai","year":"1994","journal-title":"Indian J Physiol Pharmacol"},{"key":"R23-20260512","article-title":"How Yoga Helps in the Endocrine System","year":"2015","journal-title":"The Yoga Mandala"},{"key":"R24-20260512","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1089\/acm.2010.0676","article-title":"Impact of Yoga Nidra on menstrual abnormalities in females of reproductive age","volume":"19","author":"Rani","year":"2013","journal-title":"J Altern Complement Med"},{"key":"R25-20260512","first-page":"241","article-title":"Effect of yogic practices on liver function parameters","volume":"6","author":"Sharma","year":"2017","journal-title":"International Journal of Yoga and Allied Sciences"},{"key":"R26-20260512","article-title":"Polycystic ovarian syndrome","author":"Wang","year":"2020","journal-title":"IntechOpen"},{"key":"R27-20260512","doi-asserted-by":"crossref","first-page":"139","DOI":"10.4103\/ijoy.IJOY_62_16","article-title":"Study to evaluate the changes in polycystic ovarian morphology after naturopathic and yogic interventions","volume":"11","author":"Ratnakumari","year":"2018","journal-title":"Int J Yoga"},{"key":"R28-20260512","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1089\/acm.2011.0868","article-title":"Effects of a holistic yoga program on endocrine parameters in adolescents with polycystic ovarian syndrome: A randomized controlled trial","volume":"19","author":"Nidhi","year":"2013","journal-title":"J Altern Complement Med"},{"key":"R29-20260512","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1055\/s-0031-1291208","article-title":"Exercise decreases anti-m\u00fcllerian hormone in anovulatory overweight women with polycystic ovary syndrome: A pilot study","volume":"43","author":"Moran","year":"2011","journal-title":"Horm Metab Res"},{"key":"R30-20260512","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1530\/eje.1.02024","article-title":"Clinical and psychological correlates of quality-of-life in polycystic ovary syndrome","volume":"153","author":"Hahn","year":"2005","journal-title":"Eur J Endocrinol"},{"key":"R31-20260512","article-title":"Mindful Yoga Reduces Testosterone by 29% in Women with Polycystic Ovary Syndrome","journal-title":"EurekAlert!"},{"key":"R32-20260512","doi-asserted-by":"crossref","first-page":"e8","DOI":"10.1159\/000324407","article-title":"Inflammatory gene expression in OVE26 diabetic kidney during the development of nephropathy","volume":"119","author":"Yang","year":"2011","journal-title":"Nephron Exp Nephrol"},{"key":"R33-20260512","first-page":"97","article-title":"Effect of Yoga-Nidra on blood glucose level in diabetic patients","volume":"53","author":"Amita","year":"2009","journal-title":"Indian J Physiol Pharmacol"},{"key":"R34-20260512","doi-asserted-by":"crossref","first-page":"163","DOI":"10.4103\/0973-6131.183705","article-title":"Kapalabhati pranayama: An answer to modern day polycystic ovarian syndrome and coexisting metabolic syndrome?","volume":"9","author":"Ansari","year":"2016","journal-title":"Int J Yoga"},{"key":"R35-20260512","doi-asserted-by":"crossref","first-page":"173","DOI":"10.4103\/2348-8093.143474","article-title":"Role of yoga in hormonal homeostasis","volume":"1","author":"Mahajan","year":"2014","journal-title":"Int J Clin Exp Physiol"},{"key":"R36-20260512","doi-asserted-by":"crossref","DOI":"10.1515\/jcim-2017-0098","article-title":"Effect of yoga and naturopathy on liver, renal and cardiorespiratory functions of a patient with hepatic cirrhosis with portal hypertension and ascites: A case report","volume":"15","author":"Revadi","year":"2018","journal-title":"J Complement Integr Med"},{"key":"R37-20260512","doi-asserted-by":"crossref","first-page":"2479","DOI":"10.1210\/jcem.83.7.4917","article-title":"Androgen receptor gene expression in the primate ovary: Cellular localization, regulation, and functional correlations","volume":"83","author":"Weil","year":"1998","journal-title":"J Clin Endocrinol Metab"},{"key":"R38-20260512","doi-asserted-by":"crossref","first-page":"41","DOI":"10.31887\/DCNS.2018.20.1\/klrooney","article-title":"The relationship between stress and infertility","volume":"20","author":"Rooney","year":"2018","journal-title":"Dialogues Clin Neurosci"},{"key":"R39-20260512","doi-asserted-by":"crossref","first-page":"e67","DOI":"10.1016\/j.fertnstert.2018.07.203","article-title":"Impact of yoga- and meditation-based lifestyle intervention on depression, quality of life, and cellular aging in infertile couples","volume":"110","author":"Tolahunase","year":"2018","journal-title":"Fertil Steril"},{"issue":"Suppl 4","key":"R40-20260512","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/S0015-0282(03)01138-5","article-title":"Yoga: An adjunct to infertility treatment","volume":"80","author":"Khalsa","year":"2003","journal-title":"Fertil Steril"}],"container-title":["International Journal of Yoga"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijoy.ijoy_88_23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T16:26:40Z","timestamp":1786724800000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijoy.ijoy_88_23"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5]]},"references-count":40,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.4103\/ijoy.ijoy_88_23","relation":{},"ISSN":["0973-6131","2231-2714"],"issn-type":[{"value":"0973-6131","type":"print"},{"value":"2231-2714","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5]]},"assertion":[{"value":"2023-05-24","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-11-08","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}