{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:39:58Z","timestamp":1786649998023,"version":"build-2736575974"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>This case report investigates mania and parkinsonism induced by olanzapine and disulfiram in a patient with substance use disorder. DSM-5 criteria were used for the diagnosis of drug-induced parkinsonism, and movement disorder severity was assessed with the Simpson\u2013Angus Scale. After initiating olanzapine and disulfiram therapy, the patient developed extrapyramidal symptoms and manic features. Naranjo scale indicated a probable drug reaction (score = 7), while Hartwig Severity Assessment (Level 4) suggested that hospitalization was required and these reactions were nonpreventable. The case underscores the need for vigilant monitoring and tailored treatment in patients with psychiatric conditions.<\/jats:p>","DOI":"10.4103\/ijp.ijp_1041_24","type":"journal-article","created":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T16:00:26Z","timestamp":1767801626000},"page":"77-80","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Drug-induced mania and parkinsonism in substance use disorder patient: A case report"],"prefix":"10.4103","volume":"58","author":[{"given":"Ragesh","family":"Gurumoorthi","sequence":"first","affiliation":[{"name":"Department of Pharmacy Practice, Chettinad School of Pharmaceutical Sciences, Chettinad Academy of Research and Education, Kelambakkam, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramakrishnan Subbaraya","family":"Rajendran","sequence":"additional","affiliation":[{"name":"Department of General Medicine, Sri Ramachandra Medical College and Hospital, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akila","family":"Murugan","sequence":"additional","affiliation":[{"name":"Department of General Medicine, Sri Ramachandra Medical College and Hospital, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karthik","family":"Thiyagarajan","sequence":"additional","affiliation":[{"name":"Department of General Medicine, Sri Ramachandra Medical College and Hospital, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhasaparur Ganesan","family":"Rajanandh","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Practice, SRM College of Pharmacy, Faculty of Medicine and Health Sciences, SRM Institute of Science and Technology, Kattankulathur, Chengalpattu, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,1,7]]},"reference":[{"key":"R1-20260109","first-page":"667","article-title":"Drug-induced extrapyramidal syndromes","volume":"45","author":"Jones","year":"1956","journal-title":"Ann Intern Med"},{"key":"R2-20260109","first-page":"58","article-title":"Olanzapine in the treatment of schizophrenia:Risk of extrapyramidal symptoms","volume":"220","author":"Hayes","year":"2020","journal-title":"Schizophr Res"},{"key":"R3-20260109","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/s12995-025-00454-9","article-title":"Exposure to disulfiram and incidence of parkinsonism","volume":"20","author":"D'Errico","year":"2025","journal-title":"J Occup Med Toxicol"},{"key":"R4-20260109","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1038\/clpt.1981.154","article-title":"Amethod for estimating the 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bipolar disorder","volume":"63","author":"Faden","year":"2021","journal-title":"Med Lett Drugs Ther"},{"key":"R9-20260109","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.ejphar.2018.08.007","article-title":"Pharmacological treatments for opiate and alcohol addiction:A historical perspective of the last 50 years","volume":"836","author":"Blanco-Gand\u00eda","year":"2018","journal-title":"Eur J Pharmacol"}],"container-title":["Indian Journal of 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