{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:27:11Z","timestamp":1787772431180,"version":"build-2784847793"},"reference-count":50,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:title>Abstract:<\/jats:title>\n                  <jats:p>\n                    <jats:italic toggle=\"yes\">Thymus serpyllum<\/jats:italic>\n                    L. from the Lamiaceae family is an underexplored perennial medicinal shrub with traditional usage in treating respiratory and gastrointestinal issues in the upper foothills of India. This review aims to provide a comprehensive assessment of current knowledge concerning the traditional uses, phytochemistry, and pharmacology of\n                    <jats:italic toggle=\"yes\">T. serpyllum<\/jats:italic>\n                    . The primary objective is to collect updated information on this plant and encourage further\n                    <jats:italic toggle=\"yes\">in vivo<\/jats:italic>\n                    and\n                    <jats:italic toggle=\"yes\">in vitro<\/jats:italic>\n                    research to validate local claims. Notably, the essential oil derived from\n                    <jats:italic toggle=\"yes\">T. serpyllum<\/jats:italic>\n                    has gained significant attention as a plant-derived product due to its diverse pharmacological properties, including antioxidative, antimicrobial, anti-inflammatory, and anticancer activities. Ethnomedicinal research revealed a vast scope of\n                    <jats:italic toggle=\"yes\">T. serpyllum<\/jats:italic>\n                    in developing new drugs to address numerous health sector challenges. While\n                    <jats:italic toggle=\"yes\">T. serpyllum<\/jats:italic>\n                    has been used widely, pharmacological studies are not enough. Most studies are either\n                    <jats:italic toggle=\"yes\">in vivo<\/jats:italic>\n                    or\n                    <jats:italic toggle=\"yes\">in vitro<\/jats:italic>\n                    . More studies are required to assess these medicinal claims through well-planned pharmacological experiments. This review will provide the groundwork for future research. While\n                    <jats:italic toggle=\"yes\">T. serpyllum<\/jats:italic>\n                    has been put to considerable conventional use, pharmacological studies are insufficient; most studies are either\n                    <jats:italic toggle=\"yes\">in vivo<\/jats:italic>\n                    or\n                    <jats:italic toggle=\"yes\">in vitro<\/jats:italic>\n                    . More compound isolation, comprehensive pharmacological analysis, and exploration of food applications are vital areas to investigate.\n                  <\/jats:p>","DOI":"10.4103\/ijp.ijp_220_22","type":"journal-article","created":{"date-parts":[[2024,5,23]],"date-time":"2024-05-23T15:55:37Z","timestamp":1716479737000},"page":"385-394","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":16,"title":["A comprehensive review on traditional applications, phytochemistry, pharmacology, and toxicology of Thymus serpyllum"],"prefix":"10.4103","volume":"55","author":[{"given":"Deeksha","family":"Salaria","sequence":"first","affiliation":[{"name":"Department of Biotechnology, Faculty of Applied Sciences and Biotechnology, Shoolini University of Biotechnology and Management Sciences, Solan, Himachal Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajan","family":"Rolta","sequence":"additional","affiliation":[{"name":"Department of Biotechnology, Faculty of Applied Sciences and Biotechnology, Shoolini University of Biotechnology and Management Sciences, Solan, Himachal Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uma Ranjan","family":"Lal","sequence":"additional","affiliation":[{"name":"Department of Natural Products, National Institute of Pharmaceutical Education and Research, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamal","family":"Dev","sequence":"additional","affiliation":[{"name":"Department of Biotechnology, Faculty of Applied Sciences and Biotechnology, Shoolini University of Biotechnology and Management Sciences, Solan, Himachal Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vikas","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Biotechnology, Faculty of Applied Sciences and Biotechnology, Shoolini University of Biotechnology and Management Sciences, Solan, Himachal Pradesh, India"},{"name":"Department of Biotechnology, University Institute of Biotechnology, Chandigarh University, Mohali, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,12,27]]},"reference":[{"key":"R1-20240903","first-page":"125","article-title":"Therapeutic uses of Ocimum sanctum Linn (Tulsi) with a note on eugenol and its pharmacological actions:A short review","volume":"49","author":"Prakash","year":"2005","journal-title":"Indian J Physiol Pharmacol"},{"key":"R4-20240903","first-page":"105","article-title":"Baritaux Study of various essential oils of Moroccan 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