{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T14:42:09Z","timestamp":1786718529693,"version":"build-2736575974"},"reference-count":22,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Indian J Pharmacol"],"published-print":{"date-parts":[[2018]]},"DOI":"10.4103\/ijp.ijp_29_17","type":"journal-article","created":{"date-parts":[[2018,4,30]],"date-time":"2018-04-30T04:55:42Z","timestamp":1525064142000},"page":"22","source":"Crossref","is-referenced-by-count":10,"title":["Reduced synovial inflammation and inhibition of matrix metalloproteinases explicates anti-osteoarthritis activity of polyherbal formulations"],"prefix":"10.4103","volume":"50","author":[{"given":"DhanashriR","family":"Ingale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"PriyaG","family":"Kulkarni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"SoumyaJ","family":"Koppikar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"AbhayM","family":"Harsulkar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"AlpanaS","family":"Moghe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"SureshD","family":"Jagtap","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"key-10.4103\/0253-7613.231476-1","first-page":"3316","volume-title":"Prevalence of knee osteoarthritis patients in Mysore city, Karnataka","author":"Radha","year":"2015","journal-title":"Int J Recent Sci Res"},{"key":"key-10.4103\/0253-7613.231476-2","first-page":"625","volume-title":"The role of synovitis in pathophysiology and clinical symptoms of osteoarthritis","author":"Sellam","year":"2010","journal-title":"Nat Rev Rheumatol"},{"key":"key-10.4103\/0253-7613.231476-3","first-page":"1595","volume-title":"Identification of novel anti-inflammatory agents from ayurvedic medicine for prevention of chronic diseases: \u201creverse pharmacology\u201d and \u201cbedside to bench approach","author":"Aggarwal","year":"2011","journal-title":"Curr Drug Targets"},{"key":"key-10.4103\/0253-7613.231476-4","first-page":"227","volume-title":"Critical appraisal of the MTT assay in the presence of rottlerin and uncouplers","author":"Maioli","year":"2009","journal-title":"Biol Proced Online"},{"key":"key-10.4103\/0253-7613.231476-5","first-page":"755","volume-title":"Hyaluronidase and collagenase inhibitory activities of the herbal formulation Triphala guggulu.J","author":"Sumantran","year":"2007","journal-title":"BiosciIndian Acad Sci"},{"key":"key-10.4103\/0253-7613.231476-6","first-page":"426","volume-title":"Bemerkungenzu der abhandlung der HH.Weselky und benedikt uebereinige azoverbindungen","author":"Griess","year":"1879","journal-title":"Ber Dtsch Chem Ges"},{"key":"key-10.4103\/0253-7613.231476-7","first-page":"103","volume-title":"Exploration of the wound healing potential of helichrysum graveolens [Bieb.) Sweet: Isolation of apigenin as an active component","author":"S\u00fcntar","year":"2013","journal-title":"J Ethnopharmacol"},{"key":"key-10.4103\/0253-7613.231476-8","first-page":"1864","volume-title":"Clioquinol and docosahexaenoic acid act synergistically to kill tumor cells","author":"Ding","year":"2006","journal-title":"Mol Cancer Ther"},{"key":"key-10.4103\/0253-7613.231476-9","first-page":"149","volume-title":"Comparative effectiveness of a complex ayurvedic treatment and conventional standard care in osteoarthritis of the knee\u2013study protocol for a randomized controlled trial","author":"Witt","year":"2013","journal-title":"Trials"},{"key":"key-10.4103\/0253-7613.231476-10","first-page":"S2","volume-title":"Nitric oxide in inflammation and pain associated with osteoarthritis","author":"Abramson","year":"2008","journal-title":"Arthritis Res Ther"},{"key":"key-10.4103\/0253-7613.231476-11","first-page":"419","volume-title":"Prostaglandins and bone: Physiology and pathophysiology","author":"Raisz","year":"1999","journal-title":"Osteoarthritis Cartilage"},{"key":"key-10.4103\/0253-7613.231476-12","first-page":"535","volume-title":"Nitric oxide and inflammatory mediators in the perpetuation of osteoarthritis","author":"Abramson","year":"2001","journal-title":"Curr Rheumatol Rep"},{"key":"key-10.4103\/0253-7613.231476-13","first-page":"9","volume-title":"Nitric oxide synthases and osteoarthritis","author":"Scher","year":"2007","journal-title":"Curr Rheumatol Rep"},{"key":"key-10.4103\/0253-7613.231476-14","doi-asserted-by":"crossref","unstructured":"Gokay NS, Yilmaz I, Komur B, Demiroz AS, Gokce A, Devisoglu S, et al. A Comparison of the effects of neuronal nitric oxide synthase and inducible nitric oxide synthase inhibition on cartilage damage. BioMed Res Int 2016. Article ID: 7857345, 8.","DOI":"10.1155\/2016\/7857345"},{"key":"key-10.4103\/0253-7613.231476-15","first-page":"247","volume-title":"The role of nitric oxide in osteoarthritis","author":"Vuolteenaho","year":"2007","journal-title":"Scand J Rheumatol"},{"key":"key-10.4103\/0253-7613.231476-16","first-page":"659","volume-title":"Characterization of bacillus subtilis isolated from Asian fermented foods","author":"Phromraksa","year":"2009","journal-title":"Food SciTechnol Res"},{"key":"key-10.4103\/0253-7613.231476-17","first-page":"27","volume-title":"Anti-collagenase, anti-elastase and anti-oxidant activities of extracts from 21 plants","author":"Thring","year":"2009","journal-title":"BMC Complement Altern Med"},{"key":"key-10.4103\/0253-7613.231476-18","first-page":"1375","volume-title":"Antiarthritic activity of a standardized, multiherbal, ayurvedic formulation containing boswellia serrata:In vitro studies on knee cartilage from osteoarthritis patients","author":"Sumantran","year":"2011","journal-title":"Phytother Res"},{"key":"key-10.4103\/0253-7613.231476-19","first-page":"12367","volume-title":"Effects of high intensity exhaustive exercise on SOD, MDA and NO levels in rats with knee Osteoarthritis","author":"Li","year":"2015","journal-title":"Genet Mol Res"},{"key":"key-10.4103\/0253-7613.231476-20","first-page":"179","volume-title":"Assessment of lipid peroxidation and antioxidant status in rheumatoid arthritis and osteoarthritis patients","author":"El-barbaryAM,","year":"2011","journal-title":"Egypt Rheumatol"},{"key":"key-10.4103\/0253-7613.231476-21","first-page":"147","volume-title":"Estimation of total phenolics and flavonoids and antioxidant potential of Ashwagandharishta prepared by traditional and modern methods","author":"Tiwari","year":"2013","journal-title":"Asian J Pharm Ana"},{"key":"key-10.4103\/0253-7613.231476-22","first-page":"225","volume-title":"Oxidative stress and role of antioxidant in osteoarthritis and rheumatoid arthritis: A review article","author":"Dwivedi","year":"2014","journal-title":"Int J Innov Res Dev"}],"container-title":["Indian Journal of Pharmacology"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T13:36:10Z","timestamp":1786714570000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijp.IJP_29_17"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018]]}},"alternative-id":["231476"],"URL":"https:\/\/doi.org\/10.4103\/ijp.ijp_29_17","relation":{},"ISSN":["0253-7613"],"issn-type":[{"value":"0253-7613","type":"print"}],"subject":[],"published":{"date-parts":[[2018]]}}}