{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:40:04Z","timestamp":1786650004482,"version":"build-2736575974"},"reference-count":5,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Carbamazepine is widely used drug for various neurological psychiatric disorders. Aplastic anemia is its rare serious adverse effect which possess high mortality rate. This is a retrospective case study where aplastic anemia due to carbamazepine was reported. We enquired the case details and on doing the causality assessment by World Health Organization scale, concluded it as a \u201ccertain\u201d type of Adverse Drug Reaction (ADR) induced by carbamazepine. A 44-year-old male was taking carbamazepine prescribed for epilepsy for 2 years. For the last 4\u20135 months, he started having generalized weakness, easy fatiguability, shortness of breath on exertion, and pedal edema. Investigating it, further he was diagnosed with carbamazepine-induced aplastic anemia. Routine blood investigations, bone marrow findings, etiological confirmation done by treating physicians, and reporting of ADRs by pharmacologists through pharmacovigilance program may provide World Health Organization to release drug alerts so as to warrant the future use of culprit drugs.<\/jats:p>","DOI":"10.4103\/ijp.ijp_821_24","type":"journal-article","created":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T16:00:14Z","timestamp":1767801614000},"page":"74-76","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Carbamazepine-induced aplastic anemia: A rare reported adverse drug reaction"],"prefix":"10.4103","volume":"58","author":[{"given":"Anjali","family":"Kushwah","sequence":"first","affiliation":[{"name":"Department of Pharmacology, MGM Medical College, Indore, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akhilesh Pratap Singh","family":"Tomar","sequence":"additional","affiliation":[{"name":"Department of Microbiology, MGM Medical College, Indore, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meghna","family":"Shinde","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, MGM Medical College, Indore, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Preeti","family":"Acharya","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, MGM Medical College, Indore, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,1,7]]},"reference":[{"key":"R1-20260109","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1007\/s40264-016-0444-7","article-title":"Adverse-drug-reaction-related hospitalisations in developed and developing countries:A review of prevalence and contributing factors","volume":"39","author":"Angamo","year":"2016","journal-title":"Drug Saf"},{"key":"R2-20260109","doi-asserted-by":"crossref","first-page":"219","DOI":"10.4172\/2167-0501.1000219","article-title":"Hematobiochemical alterations induced by carbamazepine and phenytoin:Mini review","volume":"5","author":"Aliyu","year":"2016","journal-title":"Biochem Pharmacol"},{"key":"R3-20260109","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1097\/YIC.0000000000000097","article-title":"Prophylactic efficacy of lithium, valproic acid, and carbamazepine in the maintenance phase of bipolar disorder:A naturalistic study","volume":"31","author":"Peselow","year":"2016","journal-title":"Int Clin Psychopharmacol"},{"key":"R4-20260109","first-page":"615","article-title":"The side-effects of carbamazepine","volume":"62","author":"Gayford","year":"1969","journal-title":"Proc R Soc Med"},{"key":"R5-20260109","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1182\/blood-2006-03-005041","article-title":"Optimization of conditioning for marrow transplantation from unrelated donors for patients with aplastic anemia after failure of immunosuppressive therapy","volume":"108","author":"Deeg","year":"2006","journal-title":"Blood"}],"container-title":["Indian Journal of Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijp.ijp_821_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:00:54Z","timestamp":1786647654000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijp.ijp_821_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":5,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/ijp.ijp_821_24","relation":{},"ISSN":["0253-7613","1998-3751"],"issn-type":[{"value":"0253-7613","type":"print"},{"value":"1998-3751","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2024-09-30","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-04","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}