{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:46:49Z","timestamp":1787071609821,"version":"build-2736575974"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Diffuse lipomatosis, characterized by the widespread presence of mature adipose tissue within the thyroid, is a rare condition. The presence of adipose tissue may vary within the neoplastic nodules in cases of diffuselipomatosis. Although the etiology remains unclear, it is generally regarded as an embryological developmental anomaly. This case report presents a 68-year-old female patient presented to the Ear, Nose, and Throat (ENT) clinic with complaints of neck swelling. Ultrasonographic examination revealed an enlarged thyroid gland and a 2 cm nodule. The patient subsequently underwent the left lobectomy. Histological examination of the thyroid tissue showed diffuse lipomatosis and thyroid papillary carcinoma with adipose tissue in the stroma. In pathology practice, the presence of adipose tissue in the thyroid is a rare finding that can occur in both benign and malignant neoplasms.<\/jats:p>","DOI":"10.4103\/ijpm.ijpm_276_25","type":"journal-article","created":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T14:00:10Z","timestamp":1768831210000},"page":"159-161","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Diffuse lipomatosis of the thyroid and thyroid papillary carcinoma, lipomatous type: A case report"],"prefix":"10.4103","volume":"69","author":[{"given":"Ali","family":"M\u0131zrak","sequence":"first","affiliation":[{"name":"Department of Pathology, Haseki Training and Research Hospital, \u0130stanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,1,19]]},"reference":[{"key":"R1-20260403","first-page":"1334","article-title":"Synchronous Thyrolipoma and Papillary Thyroid Carcinoma: A Rare but Significant Event","volume":"11","author":"Kuk","year":"2021","journal-title":"Expert Rev Mol Diagn"},{"key":"R2-20260403","first-page":"e938156","article-title":"A 54-Year-Old Woman with Papillary Thyroid Carcinoma Associated with Secondary Amyloid Goiter and Thyroid Lipomatosis","volume":"23","author":"Morado","year":"2022","journal-title":"Am J Case Rep"},{"key":"R3-20260403","first-page":"e71245","article-title":"Amyloid Goiter, Papillary Thyroid Carcinoma, and Diffuse Thyroid Lipomatosis: A Case Report of a Rare Association","volume":"11","author":"Vaz","year":"2024","journal-title":"Cureus"},{"key":"R4-20260403","doi-asserted-by":"crossref","first-page":"e50","DOI":"10.4081\/rt.2013.e50","article-title":"A very unusual thyroid tumor: A nodule with mature fat, papillary hyperplasia and focal atypia","volume":"5","author":"Cacchi","year":"2013","journal-title":"Rare Tumors"},{"key":"R5-20260403","first-page":"353","article-title":"Mature Fat Containing Thyroid Lesions","volume":"12","author":"\u00c7elik","year":"2015","journal-title":"Electron J Gen Med"},{"key":"R6-20260403","first-page":"133","article-title":"Thyroid liposarcoma: A case report","volume":"7","author":"Gerard","year":"2022","journal-title":"Innov Surg Sci"},{"key":"R7-20260403","first-page":"e57896","article-title":"Diffuse Thyroid Lipomatosis and Amyloid Goiter With Incidental Papillary Thyroid Carcinoma: A Rare Case Report","volume":"16","author":"George","year":"2024","journal-title":"Cureus"},{"key":"R8-20260403","doi-asserted-by":"crossref","first-page":"380","DOI":"10.5798\/diclemedj.0921.2014.02.0435","article-title":"Mat\u00fcr Ya\u011fDokular\u0131I\u00e7eren Tiroid Lezyonlar\u0131n\u0131n Retrospektif Analizi","volume":"41","author":"Bedir","year":"2014","journal-title":"Dicle Med J"},{"key":"R9-20260403","first-page":"100","article-title":"Thyroid lesions containing mature adipose tissue:7 case reports","author":"Dere","year":"2011","journal-title":"Pam Med J"},{"key":"R10-20260403","doi-asserted-by":"crossref","first-page":"348","DOI":"10.4103\/0377-4929.162890","article-title":"Diffuse lipomatosis of the thyroid gland with papillary microcarcinoma: Report of a rare entity","volume":"58","author":"Nandyala","year":"2015","journal-title":"Indian J Pathol Microbiol"}],"container-title":["Indian Journal of Pathology and Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijpm.ijpm_276_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:49:27Z","timestamp":1787068167000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijpm.ijpm_276_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/ijpm.ijpm_276_25","relation":{},"ISSN":["0377-4929","0974-5130"],"issn-type":[{"value":"0377-4929","type":"print"},{"value":"0974-5130","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2025-03-23","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-01","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}